Immunity (copy)

Adaptive Immunity

* is the 3rd line of defense
* The triggering of specialized cells to specifically target antigens of pathogens with the aid of antibodies to create a specific immune response.
* Can be activated quickly or prolongedly

Innate immunity

* The second line of defense
* Also known as inflammation, the fast-acting response to damage of cells through the use of chemical mediators and phagocytic WBCs

Antigen

A substance on or in a pathogen that inflicts a immune response

Antibody

Immune cell origins: Lymphoid progenitor

* Natural Killer cells
* T-Lymphocytes
* B-Lymphocytes

Immune cell origins: Myeloid progenitor

* Monocytes
* Dendritic cells
* Granulocytes
* Mast cells

T-Lymphocytes

* Target cancer and viruses
* Mature and differentiate in the Thymus
* Requires direct contact with an antigen and then will proliferate and differentiate into:

1) cytotoxic T-Lymphocytes (direct destruction of antigen-carrying pathogens)

2) Helper T-Lymphocytes (enhances humoral & cell-mediated immune responses)

3) Suppressor T-Lymphocytes (inhibits humoral & cell-mediated responses to not be excessive)

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Humoral Immunity

Cell-mediated immunity

Cytotoxic T-Lymphocytes

* Attack tumour and viruses
* Direct destruction of antigen carrying pathogens

Helper T-Lymphocytes

Suppressor T-Lymphocytes

Dendritic cells

* When they come into contact with a pathogen, it will act as a phagocyte and bring the antigens displayed to T-Lymphocytes for identification, in the lymph nodes
* they are like the tattletails “hey look what I found”