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Knowledge techniques
Research
Experimentation
Studying
Testing
Research
Process that is used to obtain new knowledge
Experimentation
Process used to obtain new knowledge is accurate or correct
Studying
Process used to incorporate knowledge
Testing
Performed to measure knowledge we already have
National research act
Results from Tuskegee syphilis experiment
Established three ethical prinicples
Three Ethical Principles
Justice
Autonomy
Beneficence
Justice
How research should be performed
Autonomy
How research subjects should be treated
Beneficence
How research should help others
Medical research
Institutional review boards (IRB)
Clinical trials
Marketing and release
Clinical trials
Phase 1: pilot study
Phase 2: clinical trial protocol
Phase 3: expanded enrollment
double-blind study
-both groups receive pills to take.
-when participants are assigned a number, the researcher will be told which bottle to give the patient.
-Neither the participant nor the researcher knows which is the medicine and which is the placebo.
-That information cannot be obtained until the study is finished.
Stem Cell Research
-Embryonic stem cells
-Pluripotent
Pluripotent
-Endoderm
-Mesoderm
-Ectoderm
Anencephaly
-Central Nervous System Disorder
-Cephalic portion of the brain
-Comatose state
-UDDA criteria
-Organ transplants?
Fetal Reduction
-Multiple pregnancy
-Abortion procedures
-Selection process
Conjoined Twins
-50,000—100,000 births
-cephalopagus
-craniopagus
-ischiopagus
-parapagus
-synecephalus
-thoraco-omphalopagus
-thoracopagus
-Xiphopagus
Cloning
-Creating duplicates
-Playing God
-Creating human tissue/organs
Dolly the sheep
On July 5, 1996.
first mammal to be successfully cloned and born. The news set off a flurry of ethical debates within the scientific community and politics across the world. lived for six years before she was euthanized because of a medical condition.
Xenotransplantion
Animal to human donation
Compatibility problems
Animal Right Activists
Xenozoonosis
Cryonics
Deep freeze
UDDA criteria
Not yet reversible
Legal Future of Healthcare
U.S. has the best healthcare
Almost last in industrialized nations
World Health Organization
-Life expectancy
-Global Burden of Disease
Healthcare Reform
Uninsured Americans
Public health insurance
Medicaid
Medicare
PRACA
Patient Protection and Affordable Care Act
Sweeping healthcare changes
Impact insurance companies, employers, and individuals
Insurance companies
Too rich to be poor, too poor to be rich
Increases Medicaid eligibility to 133%
PRACA Insurance companies
Removes lifetime dollar limits
No arbitrary premium formula
Cannot deny services based on pre-existing conditions
PRACA Health Insurance Exchange
State run insurance shop
Sliding scale—for individuals
Subsidies—for employers
PRACA Shared Responsibility Clause
Individual mandate
Must have insurance or purchase insurance
No insurance, assessed a fine
PRACA Medicare
Improved Part D, Rx program
Bundled payment structure
All medical treatment bundled together
Hospital
Out-patient
Doctor office
PRACA Additional provisions
Voluntary insurance for assisted living, nursing home
Additional research and National Health Institute funding
CHIP and Medicaid enrollment simplified
Children on parent's policy until 26th birthday
Universal Healthcare
Socialized medicine
Government run insurance
Comparison of universal vs. American system
Staffing Ratios
Nursing shortage
Require staffing committees
Focus on patient acuity
Mandate specific ratios
Controversial
Patient care
Physician Hours
Other profession's hours regulated
MDs commonly awake for days at a time
No state laws exist
Accreditation Council for Graduate Medical Education (ACGME)
Conscientious Objector Bills
Ethics of healthcare professional
Decline to provide care
Exceptions apply
Most professional organizations against bills
Prescription Drug Advertising
Direct-to-consumer marketing
Television, magazines, newspaper, radio
Advertising budget in billions
Some unable to afford medications
Scientific Future of Healthcare
Nanotechnology
Robotics
Medical care in space
Nanotechnology
One billionth of a meter
Possible uses
Pharmacology
Medication delivery systems
Concerns about lack of regulatory guidelines
concept used to monitor and treat blood cells.
Robot
Currently in use, but limited
Concerns
Mechanical failure
Remote access
A man uses a computerize robot arm as part of his rehabilitation after a stroke. can automatically measure and adjust settings, based on the user's response.
Medical Care in Space
Space Nursing Society (SNS)
Surgery in space—bodily fluids and zero gravity
Sterile fields
Wound healing in zero gravity
Long-term nutrition
Psychological effects
Isolation
Living in confined spaces
anencephaly
a serious birth defect in which a baby is born without parts of the brain and skull. It is a type of neural tube defect (NTD). As the neural tube forms and closes, it helps form the baby's brain and skull (upper part of the neural tube), spinal cord, and back bones (lower part of the neural tube).
Clinical Trials
experiments or observations done in clinical research. Such prospective biomedical or behavioral research studies on human participants are designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy.
Cloning
process of generating a genetically identical copy of a cell or an organism. Cloning happens all the time in nature. In biomedical research, cloning is broadly defined to mean the duplication of any kind of biological material for scientific study, such as a piece of DNA or an individual cell.
cryonics
is the low-temperature freezing and storage of human remains, with the speculative hope that resurrection may be possible in the future. Cryonics is regarded with skepticism within the mainstream scientific community.
double-blind
A type of clinical trial in which neither the participants nor the researcher knows which treatment or intervention participants are receiving until the clinical trial is over. This makes results of the study less likely to be biased.
Fecal Reduction
the practice of reducing the number of fetuses in a multiple pregnancy, say quadruplets, to a twin or singleton pregnancy.
pluripotent
The pluripotency of biological compounds describes the ability of certain substances to produce several distinct biological responses. Pluripotent is also described as something that has no fixed developmental potential, as in being able to differentiate into different cell types in the case of pluripotent stem cells.
Research
"creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of information to increase understanding of a topic or issue. A research project may be an expansion on past work in the field.
xenotransplantation
any procedure that involves the transplantation, implantation or infusion into a human recipient of either (a) live cells, tissues, or organs from a nonhuman animal source, or (b) human body fluids, cells, tissues or organs that have had ex vivo contact with live nonhuman animal cells, tissues or organs.
conscientious objector
one who opposes bearing arms or who objects to any type of military training and service. Some conscientious objectors refuse to submit to any of the procedures of compulsory conscription.
global burden of disease
The Global Burden of Disease Study is a comprehensive regional and global research program of disease burden that assesses mortality and disability from major diseases, injuries, and risk factors. GBD is a collaboration of over 3600 researchers from 145 countries.
individual mandate
a provision within the Affordable Care Act that required individuals to purchase minimum essential coverage - or face a tax penalty - unless they were eligible for an exemption.
life expectancy
the number of years a person can expect to live. By definition, life expectancy is based on an estimate of the average age that members of a particular population group will be when they die.
lifetime dollar limits
a dollar limit on what they would spend for your covered benefits during the entire time you were enrolled in that plan. You were required to pay the cost of all care exceeding those limits.
nanomedicine
a branch of medicine that applies the knowledge and tools of nanotechnology to the prevention and treatment of disease. Nanomedicine involves the use of nanoscale materials, such as biocompatible nanoparticles and nanorobots, for diagnosis, delivery, sensing or actuation purposes in a living organism.
Robotics
interdisciplinary branch of computer science and engineering. Robotics involves design, construction, operation, and use of robots. The goal of robotics is to design machines that can help and assist humans.
socialized medicine
a healthcare system in which the government owns and operates healthcare facilities and employs the healthcare professionals, thus also paying for all healthcare services.