ch 18 prequel

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31 Terms

1
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inject antigen = causes primary immune response = memory B cells

injection

2
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what are the 5 ideal criteria for vaccines

  1. safety

  2. effectiveness

  3. painless or oral administration

  4. require only one injection

  5. affordable and accessible

3
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what does it mean for a vaccine to be considered effective

strong immunogen and stimulate immune response

4
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what are the 6 types of vaccines

  1. toxoid vaccines

  2. conjugate vaccines

  3. subunit vaccine

  4. mRNA vaccine

  5. live attenuated vaccine

  6. inactive killed vaccine

5
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inject INactive toxin to create antitoxins

toxoid vaccine

6
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example

  • TD vaccine

toxoid vaccine

7
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main vaccine + strong immunogen

conjugate vaccine

8
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example

  • pneumococcal vaccine

conjugate vaccine

9
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vaccine made up of antigenic fragments

subunit vaccine

10
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example

  • hepatitis B and pertussis vaccine

subunit vaccine

11
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inject pathogenic nucleic acid (not live) to make proteins

mRNA vaccine

12
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example

  • covid 19 vaccine

mRNA vaccine

13
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weakend pathogenn vaccine

live attenuated vaccine

14
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example

  • MMR vaccine

live attenuated vaccine

15
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vaccine with killed pathogen

inactive killed vaccine

16
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example

  • polio and influenza vaccine

inactive killed vaccine

17
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practical application looking for antigen or antibody

serological testing

18
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practical application that tests serum

serological

19
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what are the five desirable criteria for ideal serological testing

  1. high specificity and accuracy

  2. high sensitivity

  3. easy to set up and interpret

  4. high through put

  5. affordable and accessible

20
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to be highly specific and accurate means to be

non ambiguous

21
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what are the two types of serological tests

  • direct

  • indirect

22
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test for antigen

direct

23
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tests for antibody

indirect

24
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what are five common examples of serological tests

  1. precipitation reactions

  2. agglutination reactions

  3. neutralization reaction

  4. fluorescent antibody techniques

  5. elisa

  6. compliment fixation

25
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(high/ intermediate/ low sensitivity) radioimmunology

high

26
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(high/ intermediate/ low sensitivity) PCR

high

27
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(high/ intermediate/ low sensitivity) compliment fixation

high

28
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(high/ intermediate/ low sensitivity) elisa

high

29
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(high/ intermediate/ low sensitivity) agglutination reactions

intermediate

30
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(high/ intermediate/ low sensitivity) neutralization reaction

intermediate

31
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(high/ intermediate/ low sensitivity) precipitation reaction

low