Blood Group Systems Overview

Flashcards covering key concepts and details of various blood group systems, including Lewis, I, P, MNS, Kell, Duffy, Lutheran, and related antibodies.

Lewis antigens are found on __, __, and other tissues such as the pancreas, stomach, intestine, skeletal muscle, renal cortex, and adrenal glands.

lymphocytes, platelets

The two primary concerns in Lewis inheritance are and .

Lea, Leb

Lewis antigens are resistant to treatment with enzymes and .

ficin, papain

Antibodies associated with decreased RBC survival are known to cause and .

hemolytic transfusion reactions (HTR), hemolytic disease of the newborn (HDN)

The I blood group system includes antigens that may be or .

i, I

The most common phenotypes in the P blood group are and .

P1, P2

The MNS system is based on antigens located on and glycophorin.

Glycophorin A, Glycophorin B

Kell antibodies are mainly __ and clinically significant.

IgG

The Duffy blood group was named for Mr. Duffy, who was a __ who had anti-Fya.

hemophiliac

The Lu(a-b-) phenotype is considered to be __ in the Lutheran blood group system.

RARE