KREBS CYCLE ENZYME

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10 Terms

1
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Hexokinase

Phosphorylates glucose → glucose-6-phosphate (Step 1 glycolysis)

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Phosphoglucoisomerase

Converts glucose-6-phosphate → fructose-6-phosphate

3
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Phosphofructokinase-1 (PFK-1)

Phosphorylates fructose-6-phosphate → fructose-1,6-bisphosphate (Rate-limiting step!)

4
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Aldolase

Cleaves fructose-1,6-bisphosphate → DHAP + G3P

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Triosephosphate Isomerase

Interconverts DHAP ↔ G3P

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Glyceraldehyde-3-phosphate Dehydrogenase

G3P → 1,3-bisphosphoglycerate (produces NADH)

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Phosphoglycerokinase

1,3-bisphosphoglycerate → 3-phosphoglycerate (produces ATP)

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Phosphoglyceromutase

3-phosphoglycerate → 2-phosphoglycerate

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Enolase

-phosphoglycerate → phosphoenolpyruvate (PEP) (water loss)

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Pyruvate Kinase

PEP → pyruvate (produces ATP)