LEARN TO MAKE CLADOGRAM AND PRACTICE investigation 3: Comparing DNa sequences to understand evolutionary relationships with BLAST

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4 Terms

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goal of investigation

use Basic Local Alignment Search Tool and cladograms to find questions such as an organism’s closest living companion or about a gene that coexists between species

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basic setup

given a genetic sequence, you must use the online BLAST software to compare it to other sequences in their database. Results will show a ranking of the most closely related organisms (and % of their base pairs actually match)

MOST LIKELY WILL NEED YOU TO ANALYZE DATA OBTAINED FROM A HYPOTHETICAL BLAST QUERY AND MAKE A CLADOGRAM DEPICTING EVOLUTIONARY RELATEDNESS

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results

by getting the % similarity of an unknown gene with those from other organisms, you should be able to then place your unknown creature within a cladogram to show evolutionary relatedness.

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key skills

  • explain relationship between genetic sequences and evolutionary relatedness

  • draw/analyze a cladogram that shows evolutionary relationships