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Neurotransmitter
chemical messengers that cross the synaptic gaps between neurons
Cortisol
steroid hormone released by the adrenal cortex in response to stress; mobilizes internal fuel for quick use and narrows capillary pores to preserve energy
Chronic Stress
Long term elevated levels of cortisol; leads to muscle wasting, reproductive inhibition, and immunosuppression
Brain
The mass of nerve tissue that is the main control center of the nervous system; highly connected, electrically active
Evolution of Nervous System
only animals have one; neurons generate electric siganls almost exactly the same way in all animals, but number of neurons and patterns of connections differ greatly
Dendrite
highly branches extensions off neurons that receive signals
Axon
extension that transmits signals to other cells
Neuron
cell units of the brain that send and receive signals
Resting potential
the state of the neuron when not firing a neural impulse; high K+ and low Na+ in cell; cell has net negative charge
Permeability
K+ leaks out more than Na+ leaks in; more ions are leaving the cell than are entering thus establishing a more negative cell interior
Sodium -Potassium Pump
2K+ in for 3Na+ out
Depolarization
The process during the action potential when sodium is rushing into the cell causing the interior to become more positive
Absolute threshold
the minimum intensity of stimulation that must occur before you experience a sensation
Action Potential
a neural impulse; a brief electrical charge that travels down an axon
Resting/Action Potential Process
1. Resting state: ion channels are closed
2. depolarization: stimulus opens Na+ channels
3. Rising phase: depolarization opens more Na+ channels, while K+ remains closed; cell interior becomes more positive than outside
4. Falling phase: most Na+ inactivate, but most K+ channels stay open allowing K+ to exit the cell so it becomes more negative again
5. Undershoot: Na+ channels close, K+ channels stay open, returning cell membrane to resting state
How are action potentials propogated?
One part of the neuron triggers the next in a chain reaction; the positive charge travels down the axon at roughly 60mph
Myelin Sheath
A layer of fatty tissue segmentally encasing the fibers of many neurons; enables faster transmission speed of neural impulses to 200mph
Synapse
the junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron
Excitatory Neurotransmitter Process
1. Ca2+ within synaptic gap enters sending neuron to trigger synaptic vesicles to release neurotransmitters
2. Neurotransmitter binds onto receptor, opening ion channel
3. Na+ rushes into sending cell, making it more positive
4. Neurotransmitter unlatches from cell, closing ion channel
Inhibitory Neurotransmitter
Causes K+ to exit cell, making electrical charge of a cell more negative
Knee Reflex
1. Sensory receptors in knee receives signal of being hit
2. Sensory neurons in brain passes message to knee muscles
3. Excitatory neuron causes quadriceps muscles to contact
4. Inhibitory neurons inhibits flexors from moving, forcing the knee to move in a forward motion
Temporal summation
One neuron transmits impulses in rapid-fire order, add up together to trigger action potential
Spatial summation
The sum of multiple synapses firing at different locations at one time to create an action potential
Acetylcholine (ACh)
neurotransmitter that triggers muscle contractions; is inhibited by botox
Sarin gas
inhibits acetylcholine esterase (enzyme that breaks down ACh), forcing repeated muscle contractions; can be fatal
Sensory Transduction
converting a stimulus into an electrical charge in a cell
Modality
kind of stimulus
Intensity
how much stimulus