Signalling in the Nervous System - Chemical Signalling (round 1)

Why is there a gap between neurons?

to not produce an instantaneous response

What are two types of chemical signalling?

synaptic, non-synaptic

What components does chemical signalling require?

chemical signals released by a cell, receptors

How can chemical agents be classed in chemical signalling?

water-soluble, lipid-soluble

Define receptors

specialised structures on the target cell for chemicals to bind to

Where are receptors for water soluble chemicals located and why?

on the cell membrane because water soluble chemicals cannot penetrate the membrane

What are normal chemicals that bind to binding sites on receptors called?

ligand/ agonist

How do agonist drugs/ medication work?

binds to elicit similar response to natural ligand

How do antagonist drugs/ medication work?

blocks the binding site to prevent response

What are regulatory sites?

regions that bind other chemicals to influence effects of main ligand

What is GABA and what is its role?

gamma-amino-butyric-acid, inhibitory transmitter

What regulatory agents enhance the effects of GABA?

benzodiazepines, barbiturates