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Anatomy & Physiology
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Each time the heart contracts, about ___ milliliters are ejected and begin circulation
70
The average cardiac output is ___ liters per minute
5.25
The ventricles are ___ and ____ than the atria.
Larger and thicker
All blood exiting the heart leaves through an ____. All blood enters the heart through a ____.
Artery
Vein
The heart is kept in place and prevented from over-expanding by the _____.
Pericardium
Valleys are seen on the heart known as ___. Which are where coronary vessels can pass along the heart surface.
Sulci
The _____ _____ divides the atria and ventricles.
Coronary sulcus
The ______ ____ divides the left and right ventricles.
Interventricular Sulci
The myocardium is thickest in the _____ _____ and thinnest in the _____.
Left Ventricle
Atria
The _____ ____ houses the major electrical pathways of the heart.
Interventricular Septum
The ____ _____ is the receptacle for deoxygenated blood.
Right Atrium
Blood from the upper body enters through the ______ ___ ___ while the blood from the lower body enters through the _______ ____ ____.
Superior Vena Cava
Inferior Vena Cava
To match the leaflets of the valves, ____ ____ prevent them from relapsing.
Papillary muscles
The ___ ___ receives oxygenated blood from four pulmonary veins.
Left atrium
The AV valves include the _____ & _____ valves.
Tricuspid
Mitral (Bicuspid)
The semilunar valves include the _____ & _____ valves.
Pulmonary
Aortic
The AV & Semilunar valves both open and close _____ which is where the “Lub Dub” sounds come from.
Simultaneously
The two AV valves close when ____, or contraction of the ventricles, start.
Systole
The ____ prevent back-flow when blood has exited the heart.
Semilunar Valves
The _____ is the layer on the inside of the heart wall as well as the valves.
Endocardium
Some of the main conducting nerve fibers travel through the _____ which is a layer below the endocardium that connects to the myocardium.
Sub-endocardium
The ____ is very thick with involuntary muscle fibers specific to the heart called ____ linked through connections called intercalated discs.
Myocardium
Myocites
The _____ is the outer layer of the heart and produces the pericardial lubricating fluid
Epicardium
The ________ takes blood from the below the diaphragm back to the heart. Movement of the ___ muscles helps squeeze blood up to the heart.
Inferior Vena Cava
Leg
The _____ Takes blood from the upper body to the ____ atrium.
Superior Vena Cava
Right
Another word for oxygen deficit
Ischemia
¼ people have an extra branch off the left circumflex artery called the _______
Posterior Interventricular Artery
The ______ artery supplies the left atrium and left ventricle.
Left Circumflex Artery
The ______ supplies the right ventricle, left ventricle, and interventricular septum.
Left anterior descending artery
The ______ artery supplies the left ventricle.
Left marginal artery
The _____ artery supplies the right ventricle and the apex.
Right marginal artery
The ______ supplies the right atrium and the right ventricle.
Right Coronary Artery
If there is a blockage of blood flow in the coronary arteries the _____ heart layers are most likely to be short on oxygen as blood flows Outside —> Inside.
Inner Heart Layers (Endocardium/Sub-Endocardium)
The term _____ means all through the heart.
Transmural
_______ means pertaining to the inner heart layers.
Sub-endocardium
The ____ ____ of a cell means the difference of charge between the outside and inside.
Resting Potential
The sodium potassium ATPase pump sends out ____ sodium ions for every ___ potassium ions. Keeping the cell steadily negative.
3
2
The normal heart resting potential is about ___ mv.
-90
Phase 0 - Rapid _____
The cell becomes rapidly positive
____ rushes in.
____ channels open.
Charge change: -90mv —> +25mv
Depolarization
Na+
Na+
Phase 1 - Initial ______
Slight drop in voltage.
____ leaves the cell
____ channels close
____ channels briefly open
Charge Change: +25mv —> 0mv
Repolarization
K+
Na+
K+
Phase 2 - ____ Phase
Membrane potential stays steady
____ open and ___ remain open
____ enters the cell while ____ leaves
Charge Change: 0mv
Plateau
Ca 2+ K+
Ca 2+ K+
Phase 3 - Repolarization
The cell returns to its ______
____ continues leaving, ____ channels close
Charge Change: 0mv —> -90mv
Resting State
K+, Ca 2+
Phase 4 - ______ ______ _______
Cell is at rest and ready for the next beat
Na+/K+ ATPase pump maintains ion balance
Most channels close, leaky ____ channels keep resting potential
Charge: -90mv
Resting Membrane Potential
K+
Muscle cells are made up of strands called _____, which contain a unit _____ & _____
Sarcomeres
Actin & Myosin
The ______ has the fastest rate of autorhythmicity so it sets the other cells’ pace too. If it fails the other cells still can set the rate, however it is much ______.
SA Node
Slower
SA Node: ____ beats/min
AV Node: ____ beats/min
Bundle of His/Bundle Branches/ Purkinje Fibers: _____ beats/min
60-100
40-55
25-40
In ____ the ventricles contract.
_____ is the time of ventricular filling.
Systole
Diastole
Pressure changes in the ventricles occur in 4 phases.
Phase 1: _____ Relaxation Phase
Phase 2: _____ ______ Phase
Phase 3: _____ ______ Phase
Phase 4: Rapid _____ _____ Phase
Isovolumic
Ventricular Filling
Isovolumic Contraction
Ventricular Ejection
Isovolumic relaxation happens when the _____ & _____ valves are closed.
Aortic & Mitral
The Maximum & Minimum Pressures in each heart chamber:
Left Ventricle: ___to ___ mm Hg
Right Ventricle: ___ to ___ mm Hg
Aorta: ___ to ___ mm Hg
15 to 120
5 to 25
80 to 120
_____ or LVEDP (Left Ventricular End Diastolic Pressure) is a measure of how much the ventricle wall is stretched at the end of diastole.
Preload
______ is the resistance the left ventricle must overcome to circulate blood.
Afterload
Preload influences ____ ____ which is the amount of blood ejected from each ventricle during systole.
Stroke Volume
____ ____ is the amount of blood the heart pumps per minute.
____ ____ = HR x SV
____ ____ = HR x End diastolic volume - End systolic volume
Cardiac Output
The _____ _____ period is a pause button on the heart’s ability to be re-stimulated and contract again.
Also, when the cell membrane’s sodium and calcium channels are inactive.
Absolute Refractory
The paper used on an ECG is designed so that each tiny square is 1mm in width and equal to ___ seconds and each 1mm in height is equal to ___ milivolts.
0.04
0.1
The P wave represents _____ ______ and the electrical activity seen when the atria ______ or begin to contract.
Atrial Diastole
Depolarize
The T wave ends with ventricular _______ and _______.
Repolarization and Systole
The width of the ____ is typically narrow representing ventricular _____ and knowing if the _____ is working right.
QRS Complex
Depolarization
AV Node
The _____ nervous system (responsible for “fight or flight”) can rapidly increase the heart rate while the _____ nervous system can ____ it.
Sympathetic
Parasympathetic
Slow
It is called a “Vagal Brake” when the ______ from the parasympathetic nervous system influences the heart to reduce its pace.
Vagus Nerve
_____ means anything can change the heart rate.
Chronotropy
______ refers to the strength/force of heart contraction.
Inotropy
_____ refers to the velocity of electricity through the heart’s conduction system.
Dromotropy