CHAPTER 7 - Performing Calculations for Compounding

Active ingredient

Produces the therapeutic effect

Inactive ingredient (excipient)

Does not produce the therapeutic effect but helps create the dosage form

Inactive ingredient functions include:

Improve taste, stability, texture

Increase shelf life

Review USP Standards for compounding (*flip over*)

What a compounding formula includes (*flip over*)

QS or QSAD

Quantity Sufficient

Think of Quantity Sufficient as a another to say:

Prepare to

Choosing the correct calculation (*flip over*)

Enlargement and Reduction formula

Conversion Factor = Desired Quantity / Current Quantity

Then

New Ingredient = Original Ingredient x Conversion Factor

Weight-in-Weight (w/w)

Both active ingredient and finished product are measured by weight (grams)

Percent strength formula

(grams of active ingredient / grams of final product) x 100

If the final product equals ? grams, the grams of the drug equal the percent

100 grams

Grams of drug formula

(% Strength / 100) x Final Weight

Grams of drug formula (INCLUDING ointment/cream/petroleum base)

(% Strength / 100) x Final Weight

Then Final Weight - Grams of drug

9 out of 10 it you will know the word problem will be an Alligation problem when there are how many percentages?

3

Alligation formula

Tic Tac Toe Method