full set wk 1-5

Diltiazem

Cardizem

Verapamil

Calan SR

Non-DHP CCB uses

Atrial fibrillation, angina, HTN

Non-DHP CCB contraindications

Cardiac shock, 2nd/3rd degree AV block, HF

Non-DHP side effects and warnings

Edema, constipation (specifically Verapamil), Gingival hyperplasia, avoid grapefruit juice

Valsartan

Diovan

Olmesartan

Benicar

Irbesartan

Avapro

Uses for ARBS

HTN

Black box warnings for ARBS

Fetal toxicity

Side effects of ARBS

Hyperkalemia, small inc. in SCr, Headache, dizziness, hypotension, slight dry cough, angioedema

ARB expanded

Angiotensin Receptor Blocker

ARBs ending

-sartan

Amlodipine

Norvasc

Nifedipine ER

Procardia XL

DHP CCB uses

HTN (main) and angina

Side effects of DHP CCB

Flushing, reflex tachycardia, peripheral edema, avoid grapefruit juice

DHP CCB expanded

Dihydropyridine Calcium Channel Blocker

DHP CCB ending

-dipine

Lisinopril

Privinil

Ramipril

Altace

Benazepril

Lotensin

Enalapril

Vasotec

Uses for ACE inhibitors

HTN, HF, Post MI

Black Box Warnings for Ace Inhibitors

Fetal toxicity

Side effects for ACE inhibitors

Hyperkalemia (inc. in k), inc. in SCr, Dry cough, Headache, dizziness, hypotension, and angioedema

ACE expanded

Angiotensin converting Enzyme

ACE

-pril

Furosemide

Lasix

Loop diuretic use

HF with edema, HTN

Loop diuretic contraindications

Sulfa allergy, Pregnacy

Loop diuretic side effects and warnings

Dec. in K, Mg, Na, Ca, Inc. in UA, LDL, TG, BG, photosensitivity, ototoxicity, monitor fluid & weight

Propranolol

Inderal XL

Timolol

Timoptic

β1 & β2 blocker use: Propranolol

Angina, cardiac arrhythmias, post MI, HTN, migraine prophylaxis, essential tremor, portal hypertension

β1 & β2 blocker use: Timolol

Open angle glaucoma, ocular HTN

β1 & β2 blocker with a high lipid solubility causing more CNS side effects is.....

Propranolol

β2 blockers affect the...

Lungs

Clonidine

Catapres

α2-Adrenergic Agonist uses

HTN, ADHD

α2-Adrenergic Agonist side effects and warnings

Do not discont. abruptly, dry mouth, somnolence, fatigue, dizziness, constipation, dec. in HR, Hypotension

Lisinopril/HCTZ

Zestoretic

Lisinopril/HCTZ Classes

ACE inhibitor + thiazide diuretic

Losartan/HCTZ

Hyzaar

Losartan/HCTZ classes

ARB + thiazide diuretic

Hydrochlorothiazide/triamterene

Maxzide

Hydrochlorothiazide/triamterene classes

Thiazide diuretic + potassium sparing diuretic

Amlodipine/benazepril

Lotrel

Amlodipine/benazepril classes

DHP CCB + ACE inhibitor

Metformin/sitagliptin

Janumet

Metformin/Sitagliptin classes

Biguanide + DPP4 inhibitor

Carvedilol

Coreg

β1, β2, and α1 Blocker use

HTN, Post-MI, HF

β1, β2, and α1 Blocker contraindications

Severe bradycardia, 2nd/3rd degree AV block

β1, β2, and α1 Blocker side effects and warnings

Do not discontinue abruptly, caution in diabetes (masks hypoglycemia), dec. in HR, hypotension, take with food

Metoprolol tartrate

Lopressor

Metoprolol Succinate

Toprol XL

Atenolol

Tenormin

β1-blocker uses

Angina, HTN, acute MI, HF (Metoprolol Succinate)

β1-blocker contraindications

Severe bradycardia, 2nd/3rd degree AV block

β1-blocker side effects and warnings

Do not stop abruptly, caution in diabetes (masks hypoglycemia), decr. In HR, hypotension

β1-blocker is....

Preferred in pts with asthma/COPD

Metoprolol tartrate & Succinate should be....

Taken with food

β1-blocker affects the...

Heart

Thiazide diuretic ending

-zide and sometimes -one

Hydrochlorothiazide

Microzide

Chlorthalidone

Hygotron

Thiazide diuretic uses

HTN, Edema

Thiazide diuretics contraindications

Sulfa allergy, pregnancy

Thiazide diuretics side effects and warnings

Dec. in K, Mg, Na, Inc. I'm Ca, UA, LDL, TG, BG, and photo synthesis

Thiazide diuretic counseling points

take in the morning (avoid nocturnal urination), Avoid with NSAIDs

Hydralazine

Apresoline

Peripheral/ direct vasodilator use

Hypertension

Peripheral/ direct vasodilator side effects and warnings

Flushing, reflex tachycardia, peripheral edema, headache, drug-induced lupus erythematosus

Repaglinide

Prandin

Meglitinide use

Type 2 DM

Meglitinide Contraindications

type 1 DM, Diabetic ketoacidosis

Meglitinide side effects/ warnings

Hypoglycemia (fixed with rule of 15), do not skip meals, weight gain

Glimepiride

Amaryl

Glipizide

Glucotrol

Sulfonylurea use

Type 2 DM

Sulfonylurea contraindication

sulfa allergy

Sulfonylurea side effects/warnings

Hypoglycemia (rule of 15 helps), do not skip meals, weight gain

Liraglutide

Victoza, Saxenda

GLP-1 Receptor agonist use

Type 2 DM

Victoza (liraglutide) use

Type 2 DM

Saxenda (liraglutide) use

Chronic wgt management

Dulaglutide

Trulicity

GLP-1 Receptor agonist black boxed warnings

Risk of thyroid c-cell carsinoma

GLP-1 Receptor agonist contraindications

History of MTC (Personal/family), MEN 2

GLP-1 Receptor agonist side effects/warnings

Pancreatitis, not rec in pt w/ GI disease, weight loss, nausea, vomiting, diarrhea, avoid using w/ DPP4 inhibitors

GLP-1 Receptor agonist main route

SC Inj.

GLP-1 Receptor agonist frequency: liraglutide

Daily

GLP-1 Receptor agonist frequency: Dulaglutide

Weekly

Pioglitazone

Actos

Thiazolidinedione use

Type 2 DM

Thiazolidinedione contraindications

HF

Thiazolidinedione side effects and warnings

Peripheral edema, wgt gain, hepatic failure, risk of fractures, risk of bladder cancer