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ventilation
air transport. Getting/moving air
respiration
gas exchange. Molecules moving/diffusing
Functions of respiratory system
gas exchange, moving air, protection
nose/nasal cavity
part that takes air in
pharynx
back of throat
larynx
part of throat that blocks food
trachea
part that divides into 2 and keeps airways open
conducting portion
site of ventilation. Moving air. Nose to bronchioles
respiratory portion
site of respiration. Exchanging o2 and co2. bronchioles to alveoli
glottis
opening connecting pharynx to larynx
epiglottis
covers glottis. prevents food from entering airways. "draw bridge"
alveoli
tiny air sacs. Site of respiration. collectively make up respiratory membrane. Lots of SA. little bunches
nasal filtration
nasal cavity lined with hairs. Filters our large particles
nasal conchae
boney ridges that stir air. Warms air. sticks out to create turbulence in air flow to help remove bad particles
mucus escalator
respiratory mucosa lines conducting portion. cells produce mucus to catch particles. cilia sweep particles toward pharynx
alveolar defense
Macrophages (big eater). eat dust pathogens
o2 diffusion pathway
Alveoli --> blood --> RBC
co2 diffusion pathway
RBC --> Blood --> Alveoli
surfactant
prevents sticking. detergent breaks surface tension of water. allow alveoli to inflate.
Pneumocyte 11
what produces surfactant
equation for pressure in lungs
P= 1/V
visceral pleura
membrane that wraps lungs
parietal pleura
membrane that wraps body wall
Inhalation
diaphragm is flat. Contraction. Volume High, pressure low. P outside > P inside
exhalation
diaphragm is dome shaped. Relaxed. volume low, pressure high. P outside < P inside
pneomothorax
collapsed lung. hole in parietal pleura allows pleural cavity to fill with air. no longer potential space. air pressure pushes lung flat
ventilation formula
breaths/mins * alveolar lung volume
voluntary control of breathing
conscious effort to increase breathing rate or chest volume. Motor neurons activate diaphragm and chest muscles
involuntary control of breathing
regulated by ANS and respiratory control center in medulla. Chemoreceptors in arteries monitor CO2, o2, and H+.
as breathing increases… co2…
increases and ph decreases
if h+ increases… co2…
increases
hypercapnia
too much co2. Will result in acidosis. (exercise/lactic acid production, asthma)
hypocapnia
not enough co2. Will result in alkalosis. (hyperventilation/panic attack)
glomerulus
specialized blood vessels. Site of filtration. Knot of capillaries. No gas exchange
afferent arteriole
where blood enters
efferent arteriole
where blood exits
net filtration pressure
favors fluid diffusing from capillary to glomerular capsule. blood fluids and solutes are forced out.
blood colloid osmotic pressure (BCOP)
pressure that draws water out of filtrate and into plasma
Capsular hydrostatic pressure (CHP)
Pressure exerted on the plasma filtrate by the the elastic recoil of the glomerular capsule, which tends to push water and dissolved solutes from the plasma filtrate back into the capillaries of the glomerulus
lympathatic system
responsible for defense from pathogens. Lympth, lymphatic vessels, and nodes, tonsils, spleen, etc
immunity
ability to resist infection from disease
pathogen
anything that can make you sick
lymph
fluid component of lymphatic system. Similar to blood plasma, but fewer proteins. Capillaries are "leaky"
hydrostatic (blood pressure) forces fluid_
out into surrounding tissues
lymphedema
blockage of lymph duct. Causes interstitial fluid accumulation. Swelling and distention of tissue
elephantiasis
caused by parasite attacking lymph vessel. swelling and skin thickening
lymph nodes
small lymph organs. filter lymph before returning fluid to vena cava. They look for abnormal debris and pathogens
thymus
produces hormones to help mature lymphocytes (t cells)
spleen
functions like nodes, but filters blood not lymph. RBC graveyard. Tears easilty
WBC are also known as _
Lymphocytes
all blood cells originate from the red bone marrow stem cell called
hemocytoblasts
t cell
matures in thymus. antibody-mediated immunity. Work like antibiotics
b cell
matures in bone marrow. From vaccines and where you've traveled.
NK (natural killer)
destroys pathogens
innate immunity
born with. contains and destroys invaders. Everyone has these. Genetically determined, same response every time
adaptive immunity
t and b cells. Everyones are different. Depends on where you've been and vaccines.
interferons
chemical signals to slow infection. Signal there's an infection
complement
compliments antibody system. Works with antibodies
immunological survellience
destruction of abnormal cells by NK cells in peripheral tissures
inflammation
swelling, redness heat, pain. Can be good because it tells you something is wrong. Brings blood to infected area to help heal wound
antigens
"surface labels" that identify a cell.
major histocompatibility complect (MHC)
protein which displays antigens like a flag on plasma membrane. found on every cell and pathogen.
antibodies
specialized proteins produced by the immune system to help fight infections. They recognize and bind to specific antigens, such as bacteria or viruses, marking them for destruction by other immune cells.
antigents
substances that induce an immune response. They are typically foreign proteins or polysaccharides found on the surface of pathogens.
Rh factor
a protein found on the surface of red blood cells that determines blood type. It is important in pregnancy and blood transfusions.