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cell size as specialization
different cells are specialized in size to support their functions (average human cell is 10-30 um in diameter)
sperm
longer (50 um) but extremely narrow and small in volume
shape and volume reduces resistance, allowing it to swim
egg
largest volume (110 um) of any human cell (visible to the naked eye)
allows storage of large food reserves in cytoplasm
bird eggs have a larger storage (yolk)
red blood cells
smaller (6-8 um), indented in middle (~1 um)
size and shape allow passage through capillaries
large SA:V loads and unloads oxygen faster
white blood cells
smaller (10 um) when inactive, but enlarges (30 um) when activated
growth in volume allows increased amounts of rER and Golgi for protein synthesis (antibodies)
motor neurons
long axons (up to a meter or more)
carries signals from CNS (brain & spinal cord) to distant muscle
striated muscle fibres
larger than average (20-100 um)
allows for exertion of greater forces & contraction
SA:V
volume of the cytoplasm determines cell’s metabolism
sum of all reactions that occur
bigger the cell, higher the volume, greater the metabolism
more nutrients needed & waste produced
SA determines cell’s rate of diffusion (material exchange)
substances move in/out of cells via plasma membrane
bigger the cell, lower the membrane, greater the SA
faster solutes can enter/exit cell
when diffusion cannot keep up with metabolism, the cell dies
low SA:V means nutrients cannot enter quickly enough and waste will accumulate, thus cell divides to maintain a high SA:V
adaptations to increase SA:V
red blood cells: high SA:V allows oxygen to load & unload rapidly
its biconcave shape decreases volume, but creates shorter maximum distance to cytoplasm
proximal convoluted tubules (kidney)
inner membrane has many microvilli, which increases SA
outer membrane also has invaginations (infoldings), also increases SA
both create ample space for placement of channel and pump proteins that carry out selective reabsorption
cell division
organisms produce new cells via cell division
necessary for growth, maintenance, and reproduction
a mother cell divides into two daughter cells
every cell can be traced to zygote, the original cell
formed from fusion of sperm and egg
cell proliferation
rapid increase in number of cells when division exceeds death
growth
in animals, cell proliferation occurs during embryotic and juvenile growth, stopping once adult size is reached
growth plates in bones are during childhood and adolescence allowing increase in height
in plants, cell proliferation is limited to meristems
apical meristems are found at tips of stems and roots
some remain as meristeam and continue to divide, while others differentiate to take on specific function
cell replacement
new skin cells replace old ones that were lost due to friction
nasal layer of epidermis carries out cell division and newly produced cells are displaced towards skin surface
produces large amounts of keratin (hydrophobic) which dehydrates the cells
once surface is reached, cells are flattened and dead
tissue repair
undifferentiated stem cells can divide to heal wounds
basal layer of cells in epidermis carries out cell division and newly produced cells are displaced towards skin surface
produces large amounts of keratin (hydrophobic) which dehydrates the cells
once surface is reached, cells are flattened and dead
tissue repair
undifferentiated stem cells can divide to heal wounds
basal layer of cells can replace damaged outer layer
stem cells in dermis can repair deeper damage
if damage is severe, skin grafts may be necessary
role of mitosis and meioisis
nuclear division is necessary to avoid anucleate cells
such cells cannot grow or maintain itself, with limited lifespan (RBC)
mitosis and meiois