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Interactionist approach
Explanation that schizophrenia results from both biological vulnerability and environmental stress.
Diathesis–stress model
States that a genetic or biological predisposition (diathesis) interacts with stressors to trigger schizophrenia.
Diathesis definition
A vulnerability or predisposition, usually genetic or biological.
Stress definition
Any environmental experience that triggers the onset of schizophrenia.
Genetic diathesis
Schizophrenia strongly linked to genetic factors such as multiple risk genes.
Biological diathesis examples
Genes affecting dopamine or glutamate, prenatal infection, brain abnormalities.
Environmental stressors
Family conflict, trauma, abuse, high expressed emotion, drug use (especially cannabis).
Tienari adoption study
Found schizophrenia most likely in individuals with genetic vulnerability AND high-stress adoptive families.
Cannabis as a stressor
Cannabis use increases risk by affecting dopamine; not sufficient alone to cause schizophrenia.
Modern diathesis–stress model
Diathesis can include genetic, psychological or trauma-based vulnerability.
Childhood trauma
Physical, emotional or sexual abuse increases likelihood of schizophrenia.
Urban living stress
High population density and social stress linked to increased incidence.
Interactionist treatment approach
Combines antipsychotic medication with psychological therapies.
Medication role
Reduces biological symptoms and allows engagement in therapy.
CBT role
Helps challenge irrational beliefs and improve coping.
Family therapy role
Reduces stress and expressed emotion in the home environment.
Strength: holistic explanation
Considers both nature (biology) and nurture (environment).
Strength: strong research support
Tienari’s adoption study directly supports the diathesis–stress model.
Strength: effective treatment
Combined therapy more effective than medication or therapy alone.
Limitation: unclear mechanisms
Exact way genes and stress interact is not fully understood.
Limitation: oversimplification
Schizophrenia likely involves many interacting factors beyond simple diathesis and stress.
Limitation: treatment causation fallacy
Just because combined treatment works does not prove interactionist cause.
Overall conclusion
Best explanation of schizophrenia integrates biological, psychological and social factors.