Human Recreational Drugs: THC/Marijuana Toxicity in Pets

Flashcards covering the clinical presentation, diagnosis, treatment, and prognosis of marijuana (THC) toxicity in domestic animals based on lecture notes.

THC/Marijuana Primary Species Affected

Primarily seen in dogs, though cats are also susceptible.

Onset of Clinical Signs (Ingestion)

Clinical signs typically begin within $30\,\text{min}$ of ingestion.

Onset of Clinical Signs (Inhalation)

Clinical signs typically begin within approximately $10\,\text{min}$ of inhalation.

Classic THC Toxicity Presentation

Characterized by hyperesthesia, ataxia, dysphoria, bradycardia, and urine dribbling.

High-Dose THC Symptoms

Rapid progression to hypotension and obtundation.

Duration of THC Clinical Signs

Can last up to $72\,\text{h}$, but typically persists for $18$ to $24\,\text{h}$.

Urine Drug Test for THC

Over-the-counter human urine drug tests are specific but insensitive, often resulting in false negatives in pets.

THC Toxicity Treatment (Decontamination)

Includes the administration of emesis and activated charcoal (AC).

Supportive Care for THC Toxicity

Includes IV fluids, heat and bedding support, and maintaining a low-stimulation environment.

Antiemetics in THC Toxicity

Used to decrease the risk of aspiration pneumonia.

Intralipids

A treatment option that may be considered specifically with synthetic marijuana ingestion.

THC Mechanism of Action

Works at a unique brain receptor to cause CNS signs and increases other neurotransmitter activity.

Prognosis of THC Toxicity

Excellent.