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The central nervous system (brain and spinal cord) is stabilized/protected by…
tissue and fluid surrounding it
Meninges

Meninges
3 layers of membranes that:
protect and hold the brain and spinal cord in place
suspend and anchor the CNS within the skull
contain layer of Cerebrospinal fluid
provide nourishment

Meninges run down length of…
the spinal cord
Cerebrospinal Fluid function
cushion and makes brain buoyant
3 Layers of Meninges
Dura
Arachnoid
Pia
Dura Mater
Top Layer of Meninges (thicker, strong)
Serves as mechanical support
2 layers
Divides Cranium into 3 parts (Cerebral Subdivisions)
What 2 layers make up the Dura Mater?
Periosteal
Meningeal
Periosteal Layer
top layer, attached to the inside of the skull
tougher/”steel”
Meningeal Layer
inner layer, underneath the periosteal layer
where other meninges are
The two dura layers separate in some places to create what?
venous sinuses
What do the Venous Sinuses do?
drain blood away from the brain
3 Dura Cerebral Subdivisions
Falx Cerebri
Falx Cerebelli
Tentorium Cerebelli

Falx Cerebri
separates the two hemispheres of the brain
located in the longitudinal fissure
think: “cerebrum”
attaches to base of skull and stabilizes
down the middle of brain

Falx Cerebelli
lies between the left and right cerebral hemisphere
think: “cerebellum”
attaches to base of skull and stabilizes
down the middle of brain

Tentorium Cerebelli
think cerebellum
separates occipital lobe from cerebellum
separates the cerebellum and brainstem from the cerebrum
tent=cover

Arachnoid Mater
Middle layer of meninges (ceran wrap/more delicate)
bridge over sulci and gyri (SPIDERY PICTURE ON QUIZ)
forms protective barrier around brain
Arachnoid Trabeculae
Leptomeninges
Subarachnoid Space

What ties the Arachnoid Layer to Pia Layer?
Arachnoid Trabeculae
Arachnoid + Pia Mater = ?
Leptomeninges
hard to separate the 2 layers, so they get that name

What is the space between the arachnoid mater and pia mater called? What does it contain?
Subarachnoid Space; Cerebrospinal Fluid (CSF)
Pia Mater
Innermost layer of meninges (thin layer)
tightly hugs brain and spinal cord
follows brain's surface, including the sulci (grooves)
goes deep into the grooves of the brain

Which of the following make up the leptomeninges?
arachnoid and pia mater

Label Layers “Think About It”

What is Cerebral Spinal Fluid?
clear fluid that surrounds/protects the brain and spinal cord
produced by the choroid plexus (in brain's ventricles)

What does CSF do?
acts like a cushion
Helps control pressure inside the skull.
nourishes nervous tissue
removes waste from nervous tissue
Ventricular System
network of cavities (spaces) inside the brain
cavities that allow cerebrospinal fluid (CSF) to flow through the brain
4 Major Ventricles

The 4 Major Ventricles
2 Lateral Ventricles
3rd Ventricles
4th Ventricle
Lateral Ventricles
2 lateral ventricles → one on each side of the brain (bilateral)
C-shaped
Located in Parietal lobe, extend to frontal/temporal lobes

Lateral ventricles connect to 3rd ventricle by what?
interventricular foramen

Each lateral ventricle contains a what?
choroid plexus (projects medially into cavity)

3rd Ventricle
narrow space located between the two thalami

3rd Ventricle connects to 4th Ventricle through what?
cerebral aqueduct

Where is the choroid plexus located on on the 3rd ventricle?
above the roof

4th Ventricle
located in front of cerebellum, behind pons and upper medulla
Has 3 openings (foramina)

Three 4th Ventricle Foramina (what do they do + what are they?)
allow CSF to leave
3 Openings:
2 lateral foramina of Luschka
1 median foramen of Magendie

4th ventricle is connected to 3rd ventricle by what?
cerebral aqueduct

4th ventricle continues down where?
into central canal of spinal cord

CSF flows from the 1)______ into the 2)_______ via the 3)________.
1) lateral ventricles
2) 3rd ventricles
3) interventricular foramen

From the third ventricle, CSF flows to the ________ via the ______ in the midbrain.
1) 4th ventricles
2) cerebral aqueduct

From the fourth ventricle it can pass into the central canal of the spinal cord or into the ________ via the _______ or _________.
1) Subarachnoid Space
2) Foramen of Luschka
3) Magendie’s Foramen

Dorsal View
Anterior (Nose)
Posterior (Back of head)
“Megendies Foramen”


Think About Its Brain Label
Answers

Cerebrospinal Fluid (Origin, Structure, Circulation, Function)
Origin: Choroid Plexus
Structure: clear, colorless, suspends CNS
Circulation: from ventricles to subarachnoid space
Function: cushion between CNS and bones
after a TBI, the brain may…
swell
causes brain to push against the meninges and skull —> damages the cerebral cortex
what is another word for stroke?
cerebrovascular accidents (CVA)
Hematoma
brain bleed → blood collects in a pocket
Types:
Epidural
Subdural

Epidural Hematoma
OUTSIDE Dura
blood between the skull and dura mater
“Lemon shape”
Blood can move freely btwn hemispheres bc dura isn’t holding it in place

Subdural Hematoma
UNDER Dura
blood between the dura mater and arachnoid mater
“Banana Shape”
blood is trapped bc of dura holding it in place

PATH OF CIRCULATION
made in Choroid plexus
→ Lateral ventricles
→ Interventricular foramina
→ 3rd ventricle
→ Cerebral aqueduct
→ 4th ventricle
→ Foramen of Magendie + foramina of Luschka
→ Subarachnoid space
→ Arachnoid granulations
→ Dural venous sinuses
Love in 3s Comes 4(for) Few, So Actually Don’t
Potential Space
area between periosteal and cranium
Meningitis
“inflammation of meninges”
can be diagnosed by testing CSF
typically occurs in dura mater
CSF Drainage
drains from the subarachnoid space into the venous (blood) sinuses/system.
depends on a pressure difference
CSF is constantly produced, circulated, and absorbed to maintain a healthy balance
What makes CSF drainage pressure-sensitive?
Higher pressure in the subarachnoid space → CSF can drain into the venous system
CSF production and absorption are what? What does that mean?
independent
brain continues producing CSF regardless of how quickly it is being absorbed
Hydrocephalus
increased pressure in brain due to excessive CSF
Communicatig (no block) vs Non-Communicating (block)
Hydrocephalus Treatment
Lumbar Puncture/Spinal Tab - a needle is inserted between two vertebrae to collect CSF
Shunt (tube w/ catheder)
CSF analysis can help…
diagnose several diseases and conditions

What type of hematoma is indicated by the yellow arrow?
Epidural

What type of hematoma is this?
Subdural

What type of hematoma is this?
Epidural

What type of hematoma is this?
Subdural