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Where is the central respiratory center located?
Brainstem
Integrates information from:
Central chemoreceptors
Peripheral chemoreceptors
Mechanoreceptors
What do central chemoreceptors respond to?
Located in medulla
Respond primarily to:
↑ PaCO₂
↑ Hydrogen ions
Response → ↑ ventilation
What do peripheral chemoreceptors respond to?
Located in carotid bodies
Respond to:
Hypoxemia
CO₂ changes
H⁺ changes
Response → ↑ ventilation
What is the role of respiratory mechanoreceptors?
Monitor mechanical forces
Inhibit muscle activity when contraction force reaches potentially harmful levels