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Glia
One of two cell types that make up the nervous system; provide scaffolding, help neurons align, provide insulation, transport nutrients/waste, and mediate immune responses
Neurons
Interconnected information processors essential for all nervous system tasks
Soma (Cell Body)
Contains the nucleus of the neuron
Dendrites
Branching extensions from the soma that serve as input sites where signals are received from other neurons
Axon
Major extension from the soma that transmits electrical signals to terminal buttons
Terminal Buttons
End points of axons that contain synaptic vesicles
Synaptic Vesicles
House neurotransmitters (chemical messengers of the nervous system)
Myelin Sheath:
Coating on axons that acts as insulation, increasing signal transmission speed
Synapse
Very small space between two neurons where communication occurs
Receptors
Proteins on cell surfaces where neurotransmitters attach; have specific shapes matching specific neurotransmitters
Semipermeable Membrane
Neuron's outer surface that allows smaller/uncharged molecules through while stopping larger/charged molecules
Membrane Potential
Difference in electrical charge across the neuronal membrane
Resting Potential
State of readiness when the neuron membrane's potential is held between signals
Threshold of Excitation
Specific charge level that must be reached for a neuron to become active
Depolarization
Process when the cell's charge becomes positive or less negative
Action Potential
Electrical signal that moves from cell body down the axon to terminals; the positive spike in membrane potential
Repolarization
Process when the cell quickly returns toward resting potential as potassium ions leave
Hyperpolarization
When the cell becomes slightly more negative than resting potential
All-or-None Phenomenon
Incoming signals are either sufficient or insufficient to reach threshold; action potentials propagate at full strength
Reuptake
Process where excess neurotransmitters are reabsorbed back into the neuron
Psychoactive Drugs
Can act as agonists or antagonists for neurotransmitter systems
Agonists
Chemicals that mimic a neurotransmitter at the receptor site, strengthening its effects
Antagonists
Block or impede normal neurotransmitter activity at the receptor
Reuptake Inhibitors
Prevent unused neurotransmitters from being transported back to the neuron
Mood Disorders
Conditions where a person experiences severe disturbances in mood and emotion
Psychological Disorder
Condition characterized by abnormal thoughts, feelings, and behaviors
Psychopathology
Study of psychological disorders, including symptoms, causes (etiology), and treatment
Major Depressive Disorder
Includes depressed mood most of the day, nearly every day, and loss of interest/pleasure in usual activities
Seasonal Pattern
Depression symptoms occurring only during particular times of year
Peripartum Onset (Postpartum Depression)
Major depression during pregnancy or four weeks following childbirth
Persistent Depressive Disorder
Depressed moods most of the day, nearly every day, for at least two years
Bipolar Disorder
Mood states that vacillate between depression and mania
Unipolar
Persistently sad mood (in contrast to bipolar)
Manic Episode
Distinct period of abnormally elevated, expansive, or irritable mood with increased activity/energy lasting at least one week
Flight of Ideas
Rapid switching from one topic to another during manic episodes
Cortisol
Stress hormone released by the neuroendocrine system; often elevated in depressed individuals