Guillain-Barre Syndrome

Guillain-Barre Syndrome

What is the autoimmune disease that involves the PNS, causing damage to the Schwann cells and axons?

Myelinated

Do we see a higher conduction velocity with myelinated or unmyelinated nerves?

Motor nerves

Which type of nerves are all myelinated? (which is why with Guillain Barre syndrome we see a large impact on movement)

Intubation and Mechanical ventilation

What should be considered when FVC is less than 15 mL/kg or NIF is worse than -30 cm H2O? (w/ intensive care monitoring)

Within 4 weeks

What is the time period for Pts with GBS for clinically worsening and then hitting a plateau phase?

Increasing the metabolic demand of a nerve, decreases its reserve to heal → delay in healing

Why is there is a focus on fatigue management for GBS?

“prolonged weakness” can last up to 5 days after overload and see high CK levels

What do we see in terms of fatigue with pts who have GBS?

More strain on the muscles, high level of energy usage

Why do we avoid eccentric contractions?

increased exercise intensity

Nerve regenerate does NOT occur faster with ….

decrease demand

Usually when using PBWSTT or partial body weight support the goal is to have our patients work harder but in terms of GBS patients it is to….