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Vocabulary terms and concise definitions covering the key concepts of chromosomes and cellular reproduction from the notes.
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Prokaryote
Unicellular organism lacking a nucleus; genome is usually a single circular chromosome.
Eukaryote
Organism with a nucleus and membrane-bound organelles; DNA organized into multiple linear chromosomes.
Eubacteria
True bacteria; a major group of prokaryotes with no nucleus.
Archaea
Ancient bacteria; transcription and some processes resemble eukaryotes more than eubacteria.
Nucleus
Membrane-bound organelle that houses the genetic material in eukaryotic cells.
Histone
Protein around which DNA wraps to form chromatin in eukaryotes.
Chromatin
DNA-histone complex that condenses to form chromosomes in the nucleus.
Chromosome
DNA molecule carrying genetic information; in eukaryotes usually linear and packaged with histones.
Chromatid
One copy of a replicated chromosome; sister chromatids are held together at the centromere.
Sister chromatid
The two identical copies of a replicated chromosome held together by cohesion.
Homologous chromosomes
Pairs of chromosomes that are similar in size and gene content; one from each parent.
Diploid
Cell or organism with two sets of chromosomes (2n); typically has homologous pairs.
Haploid
Cell or organism with a single set of chromosomes (n); gametes are haploid.
Polyploid
Having more than two complete sets of chromosomes.
Centromere
constricted chromosome region where sister chromatids attach and where kinetochores form.
Telomere
Protective ends of linear chromosomes that prevent degradation and fusion.
Origin of replication
Site where DNA replication begins.
Interphase
Cell growth and DNA replication phase; includes G1, S, and G2.
M phase
Mitotic phase; nuclear and cytoplasmic division occur.
Mitosis
Nuclear division producing two genetically identical diploid daughter cells.
Cytokinesis
Division of the cytoplasm and cell contents, yielding two separate cells.
Prophase
First stage of mitosis; chromatin condenses into visible chromosomes and spindle forms.
Prometaphase
Nuclear envelope breaks down; spindle attaches to kinetochores.
Metaphase
Chromosomes align on the metaphase plate; spindle checkpoint ensures proper attachment.
Anaphase
Sister chromatids separate and move to opposite poles.
Telophase
Chromosomes arrive at poles; nuclear envelope re-forms and chromosomes de-condense.
Kinetochore
Protein structure at the centromere where spindle fibers attach.
Spindle apparatus
Microtubule-based structure that separates chromosomes during division.
Cohesin
Protein complex that holds sister chromatids together after replication.
Separase
Protease that cleaves cohesin to allow sister chromatid separation.
Shugoshin
Protein protecting centromeric cohesin during meiosis I.
Meiosis
Cell division that reduces chromosome number by half, producing haploid gametes.
Meiosis I
Reduction division; homologous chromosomes separate; crossing over occurs.
Meiosis II
Equational division; sister chromatids separate, producing haploid cells.
Crossing over
Exchange of genetic material between nonsister chromatids during prophase I.
Chiasma
Physical site of crossing over between homologous chromosomes.
Independent assortment
Random distribution of maternal and paternal chromosomes into gametes.
Fertilization
Union of two haploid gametes to form a diploid zygote.
Zygote
Diploid cell produced after fertilization; begins a new organism.
Gamete
Haploid reproductive cell (sperm or egg) that fuses during fertilization.
Spermatogenesis
Production of sperm in the testes via meiosis.
Spermatogonium
Diploid germ cell in testes that can undergo mitosis and/or enter meiosis.
Primary spermatocyte
Diploid cell that enters meiosis I.
Secondary spermatocyte
Haploid cell produced after meiosis I.
Spermatid
Haploid product of meiosis II; matures into sperm.
Oogenesis
Production of eggs in the ovaries with unequal cytokinesis.
Oogonium
Diploid germ cell in the ovary that can undergo mitosis or enter meiosis.
Primary oocyte
Diploid cell that begins meiosis I and is arrested in prophase I until puberty.
Secondary oocyte
Haploid cell produced after meiosis I; completes meiosis II upon fertilization.
Ovum
Mature egg; haploid female gamete.
Polar body
Small haploid cell produced during female meiosis that usually disintegrates.
Megasporocyte
Diploid cell in the ovary that undergoes meiosis to produce megaspores.
Megaspore
Haploid product of megasporocyte meiosis; eight nuclei form the embryo sac.
Microsporocyte
Diploid cell in the stamen that undergoes meiosis to produce microspores.
Microspore
Haploid product that develops into pollen grain.
Pollen grain
Male gametophyte; contains a tube nucleus and a generative nucleus.
Embryo sac
Female gametophyte in flowering plants; contains egg and polar nuclei.
Endosperm
Triploid tissue formed after double fertilization; stores food for the embryo.
Double fertilization
Two fertilization events in flowering plants: one forms the zygote, the other forms endosperm.
Alternation of generations
Life cycle with alternating diploid sporophyte and haploid gametophyte generations.
Sporophyte
Diploid plant generation that produces spores by meiosis.
Gametophyte
Haploid plant generation that produces gametes by mitosis.
Karyotype
Number and appearance of chromosomes in a cell, often visualized in a stained spread.
Synapsis
Pairing of homologous chromosomes during prophase I in meiosis.
Tetrad / bivalent
Group of four chromatids formed by synapsis of homologous chromosomes.
Interkinesis
短 interval between meiosis I and II when some cells do not undergo DNA replication.
Virus
Simple infectious particle without cellular structure; consists of protein coat and nucleic acid; requires a host to replicate.