White Blood Cell Metabolism

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7 Terms

1
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Define this:

  • Produces hypochlorous acid and tyrosyl radical for antimicrobial activity (critical killing method)

  • Expressed in neutrophils

  • Forms a complex in ER with calcium-binding proteins

  • Dimer of dimers tetramer

Myeloperoxidases

2
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Define this:

  • Defends against bacteria and viruses in mucosal secretions

  • Oxidizes iodide, bromide, thiocyanate and other substances while oxidizing itself

  • Created by lungs and mammary glands

  • Located in saliva and tears

Lactoperoxidase

3
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Define this:

  • Catalyzes the oxidation of halide ions using hydrogen peroxide (H2O2)

  • Release of histamine and activate neutrophil

  • Produces mainly hypobromous acid

  • Mainly killing parasites and microorganisms

Eosinophil peroxidase

4
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What are the three main white blood cells?

Basophil, Eosinophil, and Neutrophil

5
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What cells se aerobic glycolysis and no oxidative phosphorylation?

Cancer cells and White blood cells

6
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What cells go through aerobic glycolysis and oxidative phosphorylation?

Cells needing to make lipids

7
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What cells do oxidative phosphorylation and no glycolysis?

Normal Cells