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Retina
Multicellular epithelium converting light to membrane potential.
Inner Retina
Layer towards the middle of the eye.
Outer Retina
Layer towards the outside of the eye.
Outer Nuclear Layer
First layer of the retina.
Outer Plexiform Layer
Layer where synaptic connections occur.
Inner Nuclear Layer
Layer containing nuclei of bipolar cells.
Inner Plexiform Layer
Layer where bipolar cells synapse with ganglion cells.
Ganglion Cell Layer
Contains retinal ganglion cells.
Optic Disc
Blind spot where optic nerve exits retina.
Photoreceptors
Cells converting light into membrane potential changes.
Rods
Photoreceptors sensitive to low light levels.
Cones
Photoreceptors responsible for color vision.
Cone Photopigment
Coneopsin is the photopigment in cones.
Rod Photopigment
Rhodopsin is the photopigment in rods.
Fovea
Area of highest visual acuity in the retina.
Convergence
Multiple photoreceptors connect to single ganglion cell.
Color Sensitivity of Rods
Rods have no color sensitivity.
Color Sensitivity of Cones
Cones have three types for color vision.
Dark Current
Depolarization in rods due to cGMP.
Response to Light
Light causes hyperpolarization of photoreceptors.
G-Protein-Coupled-Receptor Pathway
Pathway involving rhodopsin or coneopsin.
Retinal Conversion
Light converts retinal from cis to trans.
Transducin
G protein activated during phototransduction.
Phosphodiesterase (PDE)
Enzyme breaking down cyclic GMP.
Receptive Fields
Area where a stimulus affects neuron response.
Photoreceptor Receptive Fields
Determined by lens direction; simple structure.
Retinal Ganglion Cell Receptive Fields
Circular fields responding to light spots.
Photoreceptor
Cells in the retina that detect light.
Retinal Ganglion Cell (RGC)
Neurons that transmit visual information from the retina.
Convergence
Multiple photoreceptors connect to one RGC.
M-type RGCs
Large receptive fields, sensitive to light.
P-type RGCs
Small receptive fields, specialized for color detection.
On-Center RGCs
Increase firing rate with light in the center.
Off-Center RGCs
Increase firing rate in absence of light.
Antagonistic Surround
Surround light decreases firing of center RGCs.
Graded Responses
Firing rate varies with light intensity.
Suprachiasmatic Nucleus (SCN)
Regulates circadian rhythms based on light exposure.
Superior Colliculus
Involved in reflexive orientation to visual stimuli.
Lateral Geniculate Nucleus (LGN)
Thalamic relay center for visual information.
Center-Surround Organization
RGCs respond differently to light in center vs. surround.
Fovea
Central region of the retina, high acuity vision.
Periphery of Retina
Area with larger receptive fields, more rods.
Light Sensitivity
Ability to detect low levels of light.
Divergence
Photoreceptors send outputs to various RGC types.
Bipolar Cells
Connect photoreceptors to RGCs, influence firing.
Horizontal Cells
Modulate signals between photoreceptors and RGCs.
Contrast Detection
System designed to perceive edges and borders.
Jet Lag
Disruption of circadian rhythm due to light exposure.
Reflexive Orientation
Automatic response to visual stimuli.
Visual Pathways
Parallel processing pathways established in the retina.
Light Perception
Focus on light location rather than darkness.
RGC Axons Targets
SCN, Superior Colliculus, LGN are primary targets.
Maximum Firing Rate
Occurs when light fully fills the receptive field.
Spontaneous Activity
RGCs fire at baseline rates without light.
Circadian Rhythm
Biological clock regulated by light exposure.
Thalamus
Acts as a gate for sensory information.
Primary Visual Cortex (V1)
First cortical area for visual processing.
Visuotopic Maps
Visual world representation mapped onto each eye.
Retinotopic Organization
Arrangement of visual information based on retina.
Visual Field
Total area that can be seen at once.
Hemiretina
Half of the retina, either nasal or temporal.
Axon Behavior
Pathways of axons in visual processing.
Projection Target
Destination of visual information in the brain.
Right Eye
Sees B, C; does not cross midline.
Left Eye
Sees B, C; crosses at optic chiasm.
Left Visual Hemifield
Projects to right brain structures.
Point-to-Point Representation
Adjacent neurons activate corresponding adjacent neurons.
Visual Cortices
Includes V1, V2, V3, V4, V5 for processing.
Superior Colliculus
Integrates visual and auditory information for reflexes.
Foveal Part
Represents center of visual field in SC.
Peripheral Part
Represents outer visual field in SC.
Superior Colliculus Layers
Includes visual, auditory, sensory, and motor layers.
Visual Layer
Receives visual input in superior colliculus.
Deep Layer
Initiates movement based on visual stimuli.
Visual Acuity
Sharpness of vision assessed by stimuli.
Cranial Nerves
Nerves controlling eye and neck movement.
Ocular Motor Nerve
Cranial nerve responsible for eye movement.
Response Time
Time taken for neural response to stimuli.
Temporal Summation
Combining signals over time for stronger response.
Spatial Summation
Combining signals from different locations for response.
Optic Nerve Lesion
Loss of peripheral vision on lesion side.
Optic Tract Lesion
Inability to see contralateral visual hemifield.
Optic Chiasm Lesion
Results in tunnel vision; peripheral vision loss.
Lateral Geniculate Nucleus (LGN)
Thalamic structure relaying visual information.
LGN Structure
Layered structure, six layers from deep to superficial.
Magnocellular Layers
Two layers with large, dark-staining cells.
Parvocellular Layers
Four layers with smaller cells, color-sensitive.
M-type Cells
Retinal ganglion cells projecting to magnocellular layers.
P-type Cells
Retinal ganglion cells projecting to parvocellular layers.
Contralateral Input
Input from the opposite eye.
Ipsilateral Input
Input from the same eye.
Koniocellular Layers
Receive cone inputs, specialize in color processing.
Parallel Processing Streams
Three streams: Magno, Parvo, and Konio.
Rod-driven
Magno layers respond primarily to low light.
Cone-driven
Parvo and Konio layers respond to color and detail.
Topographic Organization
Adjacent visual field points activate adjacent neurons.
Visuotopic Map
Visual space mapping in the brain.
Retinotopic Map
Visual space mapping onto the retina.
Cortical Columns
Vertical arrangements of neurons in V1.
Ocular Dominance Columns
Columns receiving input from one eye.