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Classic Meningitis triad
HA, Fever, Stiff Neck
Petechiae
< 2mm
Purpura
> 2mm
Study of choice for menigits
CSF
When should you get a CT before the LB?
Hx of CNS dx
New onset seizure
ABN LOC
Neuro deficits
Papilledema
Most common bacterial meningitis
S. pneumoniae
Empiric treatment for bacterial meningitis
Dexamethasone first
-Ceftriaxone and Vanco
0-1 mo old with menigitis
Cover GBS
Amp + 3rd gen (cefotaxamime)
Amp + aminoglycoside
What should we avoid in babies because it makes them jaundice
Ceftriaxone
Bacterial menigitis > 50/IC treatment
Amp + 3rd gen ceph + Vanco
Neisseria/Menigococcal menigitis tx
??
Prophylaxis for menigiits (kids in class have it)
Rifampin
Determine how close the student was sitting
Low sugar in CSF
Positive lympocytes
Cough, night sweats, weight loss
TB menigitis
Young baby with.a bulging fontanelle, setting sun sign, +/- serizure
GBS meningitis
Post splenectomy patient, petechial rash, bactermiae, CSF APPEARS NORMAL
Menigococcemia
Water-Friderichsen syndrome
Adrenal infraction leading to adrenal insuff from Menigococcemia
Adrenal infraction leading to adrenal insuff from Menigococcemia
Water-Friderichsen syndrome
Go over CSF findings chart
**
MC viral meningitis
Enterovirus
Abdomnal sxs, maculopapular rash
Enterovirus meningitis
Enterovirus meningitis - rash seen
maculopapular rash
Definitive dx of Viral Meningitis
PCR of viruses of CSF
Tx of viral meningitis
Supportive
NO ABX
Rash on hands and feet, CSF has lymphocytes
Coxsackie
Common in patients with AIDS/IC
Cryptococcal meningitis
Cryptococcal meningitis - concern
pressure is very high - usu CT first
India ink shows multiple round organisms with a clear halo
Cryptococcal meningitis
Tx of Cryptococcal meningitis
Ampho B
Eosinophils in LP
Aseptic meningitis 2/2 NSAIDS
MCC of encephalitis
viral
Main sx of Herpes Simplex Encephalitis
AMS
Fever, HA, seizures, AMS in a young adult could be
Herpes Simplex Encephalitis
MC viral encephalitis in young adults
Herpes Simplex Encephalitis
CT shows low density areas with mass effect localixed to the temporal lobe
Herpes Simplex Encephalitis
What does herpes love
the TEMPORAL lobe
Herpes Simplex Encephalitis - DX of choice
PCR of CSF
Herpes Simplex Encephalitis - Tx
Acyclovir. - Start ASAP
MCC of childhood encephalitis
Enterovirus encephalitis
Baby with seizures and AMS
Enterovirus encephalitis
Types of Rabies
Encephalitic
Paralytic
Which type of rabies has hydrophobia
Encephalitic
Negri bodies seen....
Rabies
Primary reservoirs for Rabies
Bats, racoons, skunks, foxes
Tx rabies
Rabies Ig /vax
Brain abscess - MC in patients with a hx of
Sinus infection
Dental infection
Facial cellulitis
MCC of brain abscess
Spread from uncontrolled infection of sinus, middle ear, mastoid cells, and teeth
Classic triad of brain abscess
fever
HA
focal neuro deficits
fever
HA
focal neuro deficits
Brain abscess
Face swollen and red w fever and HA
Brain abscess
CT shows ring enhancing lesion
Brain abscess
What is more sensative for brain abscess CT or MRI
MRI (with contrast)
Tx for brain abscess
METRO IV 4-8 weeks
Increased ICP with papilledema, otherwise negative findings
Idiopathic intracranial HTN
Idiopathic intracranial HTN aka
psuedotumor cerebri
Tx for Idiopathic intracranial HTN
LP drainage, Lasix
Gram + diplo
S.pnuemo
G - diplo
Neisseria
Unconscoius family and cat
Carbon monoxide
MCC of acute poisoing death
Carbon monoxide
India ink is used for
Cryptococcus
Pressure of LP very high with
Crypto/fungal
Lymphocytes + low sugar
TB, Listeria, Fungal, Syphilis