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Vocabulary flashcards covering water properties, carbohydrates, lipids, circulation, blood gas transport, CVD, risk factors, and exam technique.
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Water polarity
The water molecule has a partial negative charge on the oxygen and partial positive charges on the hydrogens due to unequal sharing of electrons, creating a permanent dipole.
Permanent dipole
A molecule with a constant uneven distribution of charge, giving it a positive and a negative end.
Water as solvent
Water’s polarity allows it to dissolve many substances (e.g., inorganic ions), enabling solutes to move and react.
Carbohydrates
Molecules composed of carbon, hydrogen and oxygen; long chains of sugar units (saccharides).
Monosaccharide
The simple sugar units that join to form larger carbohydrates; soluble in water.
Glucose
A common monosaccharide with six carbon atoms; main substrate for respiration.
Disaccharide
Two monosaccharides joined together by a glycosidic bond in a condensation reaction.
Maltose
A disaccharide formed by condensation of two glucose molecules.
Sucrose
A disaccharide formed by condensation of glucose and fructose.
Lactose
A disaccharide formed by condensation of glucose and galactose.
Glycosidic bond
Bond between two monosaccharides formed in condensation, containing an oxygen atom linking them.
Condensation reaction
Reaction that joins two monosaccharides with release of water to form a glycosidic bond.
Hydrolysis
Bond breaking by adding water, splitting disaccharides or polysaccharides into smaller units.
Polysaccharide
Large carbohydrate polymers made of many monosaccharides; used for energy storage or structure.
Glycogen
Main energy storage molecule in animals; highly branched with 1,4 and 1,6 glycosidic bonds.
Starch
Primary energy store in plants; mixture of amylose (unbranched) and amylopectin (branched).
Amylose
Unbranched glucose polymer with 1,4 glycosidic bonds; coiled and compact.
Amylopectin
Branched glucose polymer with 1,4 and 1,6 glycosidic bonds; many side branches for rapid digestion.
1,4 glycosidic bond
Bond between carbon 1 of one glucose and carbon 4 of the next; forms straight chains.
1,6 glycosidic bond
Bond at branching points in polysaccharides like amylopectin; creates branches.
Lipids
Non-polar biological molecules; insoluble in water but soluble in organic solvents; include fats, oils, phospholipids.
Saturated fats
Lipids with no carbon–carbon double bonds; usually solid at room temperature.
Unsaturated fats
Lipids with one or more C=C bonds; lower melting points; usually from plants.
Triglyceride
Glycerol molecule esterified to three fatty acids; major long-term energy reserve.
Glycerol
Three-carbon backbone of triglycerides.
Fatty acids
Long hydrocarbon chains with a carboxyl group; vary in length and saturation.
Ester bond
Bond formed between glycerol and fatty acids in triglycerides via condensation.
Diffusion
Movement of substances from high to low concentration across a space or membrane.
Mass transport
Systemic movement of substances (via circulatory system) to supply tissues broadly.
Circulatory system
Heart and blood vessels that transport blood and substances around the body.
Arteries
Carry blood away from the heart; thick muscular elastic walls; high pressure; no valves.
Veins
Carry blood to the heart; thin walls, large lumen, low pressure; contain valves.
Capillaries
Very small, numerous vessels with walls one cell thick; site of exchange by diffusion.
Aorta
Main artery carrying oxygenated blood from the left ventricle to the body.
Pulmonary artery
Carries deoxygenated blood from the right ventricle to the lungs.
Pulmonary vein
Carries oxygenated blood from the lungs to the left atrium.
Vena cava
Largest vein returning deoxygenated blood to the heart (superior and inferior).
Double circulatory system
Two circulatory circuits (pulmonary and systemic); blood passes through the heart twice per cycle.
Haemoglobin
Globular protein in red blood cells with four subunits and four heme groups; carries oxygen.
Partial pressure of oxygen
Measure of oxygen concentration; higher pO2 increases Hb affinity and loading of O2.
Bohr effect
Increased CO2 lowers Hb affinity for O2, promoting unloading in tissues.
Atherosclerosis
Hardening of arteries due to buildup of fibrous plaque (atheroma) narrowing vessels.
Atheroma
Fibrous plaque composed of cholesterol, calcium salts and other materials in arteries.
Thrombosis
Formation of a blood clot inside a vessel, potentially blocking blood flow.
Thrombin
Enzyme that converts fibrinogen to fibrin, forming the mesh of a blood clot.
HDL
High-density lipoprotein; helps remove cholesterol to the liver; protective against CVD.
LDL
Low-density lipoprotein; transports cholesterol to arteries; higher levels increase CVD risk.
BMI
Body Mass Index; weight (kg) divided by height (m)^2; used to classify under/normal/overweight/obese.
WHR
Waist-to-hip ratio; indicator of obesity risk; thresholds differ by sex.
Perceived risk
Subjective assessment of risk, which may differ from actual statistical risk.
Correlation vs causation
Correlation: relationship between variables; causation: one variable causes another.
Evaluating studies
Assessing study design, sample size, randomization, controls, bias, and peer review.