Chemistry

What is the name and type of reaction showed here?

\-Chichibamine reaction

\-aromatic nucleophilic substitution

What can you add to oxidize pyridine?

mCPBA

What is the type of reaction when there is Fe, HCL?

Reduction

Is Ketone para, ortho or meta orienting? and why?

Meta because it is a deactivating group

Are halogens para, ortho or meta orienting?

para and ortho

Is acyl chloride para, ortho or meta orienting?

meta

what orientation is nitro ?

meta

What orientation is alcohol?

para, ortho

what orientation is an amide?

meta favoured

What happens when you add Mg and Et2O to reaction?

The Mg adds itself to the halogen

In normal ways if we do a chlorination to a pyridine, is it para, ortho or meta favoured?

Meta favoured

What are the conditions to add NO2 to a benzene?

HNO3, H2SO4, heating

Draw MsCl (mesyl chloride)

What should you add to remove Boc? (deprotection)

Hcl, H2O

What should i add in a reaction to create a vilsmeier hack?

DMF, POCL3

what can we add using the vilsmeier hack reaction?

addition of an aldehyde

What can you add to go from an aldehyde to alcohol?

NaBH4

What does NaH act as?

A strong base

What does K2CO3 act as?

A smooth base

What can we use EtSLi for?

To replace OMe to OH

How do you get from an ester to alcohol?

NaOH and H2O (saponification)

How do you go from alkene to epoxide?

using mCPBA for oxidation

To substitute carboxylic acid to amide (add amine) we need to activate the carboxylic acid, HOW?

add SOCl2 to make acyl chloride

How can you add Cl on the pyridine ring of an isoquinolone?

add POCl3

How can you add Cl on the benzene ring of an isoquinolone?

AlCl3

What is BCl3?

A deprotonating agent