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brain
contained within the cranium, the center for coordinating body activities and comprises the cerebrum, cerebellum, and brainstem
cerebrum
largest portion of the brain, divided into left and right hemispheres. the cerebrum controls the skeletal muscles, interprets senses (such as temperature, pain, and touch), and contains centers for sight and hearing. intellect, memory, and emotional reactions also take place in the cerebrum
gray matter
outer portion of the cerebrum, contains neuron cell bodies that collect and process information. gray matter forms the inner portion of the spinal cord
white matter
inner portion of the cerebrum, contains axons, long cords that extend from neurons; conveys information to different parts of the brain. white matter forms the outer portion of the spinal cord
ventricles
cavities within the brain that contain cerebrospinal fluid (CSF). the CSF flows through the subarachnoid space around the brain and spinal cord
cerebellum
located under the posterior portion of the cerebrum; assists in the coordination of skeletal muscles to maintain balance (also called hindbrain)
brainstem
stemlike portion of the brain that connects with the spinal cord; contains centers that control respiration and heart rate. three structures comprise the brainstem: the midbrain, pons and medulla oblongata
pons
literally means bridge. it connects the cerebrum with the cerebellum and brain stem
medulla oblongata
located between the pons and spinal cord. it contains centers that control respiration, heart rate, and the muscles in the blood vessel walls, which determine blood pressure
midbrain
most superior portion of the brainstem
cerebrospinal fluid (CSF)
clear, colorless fluid contained in the ventricles that flows through the subarachnoid space around the brain and spinal cord. it cushions the brain and spinal cord from shock, transports nutrients, and clears metabolic waste
spinal cord
passes through the vertebral canal extending from the medulla oblongata to the level of the second lumbar vertebra. the spinal cord conducts nerve impulses to and from the brain and initiates reflex action to sensory information without input from the brain
meninges
three layers of membrane that cover the brain and spinal cord
dura mater
tough outer layer of the meninges
arachnoid
delicate middle layer of the meninges. the arachnoid membrane is loosely attached to the pia mater by weblike fibers which allow for the subarachnoid space
pia mater
thin inner layer of the meninges
nerve
cordlike structure made up of fibers that carries impulses from one part of the body to another. there are 12 pairs of cranial nerves and 31 pairs of spinal nerves
ganglion
group of nerve cell bodies located outside the central nervous system
glia
specialized cells located throughout the nervous system that support and nourish nervous tissue. some cells assist in the secretion of CSF and others assist with phagocytosis. they do not conduct impulses (also called neuroglia)
neuron
nerve cells that conducts impulses to carry out the function of the nervous system. Destroyed neurons in the central nervous system cannot be replaced.
cerebell/o
cerebellum
cerebr/o
cerebrum, brain
dur/o
hard, dura mater
encephal/o
brain
gangli/o; ganglion/o
ganglion
gli/o
glia
mening/o; meningi/o
meninges
myel/o
spinal cord
neur/o
nerve
poli/o
gray matter
radicul/o’; rhiz/o
nerve root (proximal end of a peripheral nerve, closest to spinal cord)
angi/o
vessel, blood vessel
blast/o
developing cell, germ cell
cephal/o
head
crani/o
cranium (skull)
embol/o
plug
esthesi/o
sensation, sensitivity, feeling
hem/o; hemat/o
blood
ment/o; psych/o
mind
mon/o
one, single
phas/o
speech
quadr/i
four
thromb/o
blood clot
inter-
between
intra-
within
para-
beside, beyond, around, abnormal
-algia
pain
-cele
hernia, protrustion
-genic
producing, originating, causing
-ictal
seizure, attack
-ism
state of
-osis
abnormal condition
-paresis
slight paralysis
-plegia
paralysis
-rrhage
excessive flow
-rrhaphy
suturing, repairing
cerebellitis
inflammation of the cerebellum
cerebral embolism
pertaining to the cerebrum, state of plug (clot of piece of plaque from a distant site lodged in a cerebral artery, causing sudden blockage of a blood vessel in the brain)
duritis
inflammation of the dura mater
encephalitis
inflammation of the brain
encephalomalacia
softening of the brain
encephalopathy
disease of the brain
encephalomyeloradiculitis
inflammation of the brain, spinal cord, and nerve roots
gangliitis
inflammation of a ganglion
glioblastoma
tumor composed of developing glia (the most malignant primary tumor of the brain)
glioma
tumor composed of glia
hydrocephalus
water (increased amount of CSF) in the head (brain)
intracerebral hemorrhage
pertaining to within the brain, excessive flow of blood (bleeding into the brain as a result of a ruptured blood vessel within the brain)
meningioma
tumor of the meninges (usually benign and slow growing, most common tumor originating in the brain and surrounding tissues)
meningitis
inflammation of the meninges
meningocele
protrusion of the meninges (through a defect in the skull or vertebral arch)
meningomyelocele
protrusion of the meninges and spinal cord (through a neural arch defect in the vertebral column) (also called myelomeningocele)
mononeuropathy
disease affecting one nerve (such as carpal tunnel syndrome)
myelitis
inflammation of the spinal cord
myelomalacia
softening of the spinal cord
neuralgia
nerve pain
neuritis
inflammation of a nerve
poliomyelitis
inflammation of the gray matter of the spinal cord (this infectious disease, commonly referred to as polio, is caused by one of three polio viruses)
polyneuritis
inflammation of many nerve
radiculitis
inflammation of the nerve roots
radiculopathy
disease of the nerve roots
rhizomeningomyelitis
inflammation of the nerve root, meninges, and spinal cord
subdural hematoma
pertaining to below the dura mater, tumor of blood (collection of blood that has leaked out of a broken vessel)
alzheimers disease (AD)
type of dementia that occurs more frequently after the age of 65, but can begin at any age. the brain shrinks dramatically as nerve cells die and tissues atrophy. the disease is slowly progressive and usually results in profound dementia in 5 to 10 years. a prominent feature of AD is the inability to remember recent past, while memories of the distant past remain intact
amytophic lateral sclerosis (ALS)
progressive muscle atrophy caused by degeneration and scarring of neurons along the lateral columns of the spinal cord that control muscles (also called Lou Gehrig disease)
bell palsy
paralysis of muscles on one side of the face caused by inflammation or compression of the facial nerve, cranial nerve VII. signs include a sagging mouth on the affected side and non closure of the eyelid; paralysis is usually temporary
botulism
serious illness caused by bacterial toxin that interferes with nerve conduction, causing skeletal muscles paralysis. initial symptoms may include trouble seeing and muscle weakness leading to difficulty swallowing and breathing. foodborne botulism, wound botulism, and infant botulism are types of the illness, all of which can be fatal and are medical emergencies
cerebral aneurysm
ballooning of a weakened portion of an arterial wall (aneurysm) in the cerebrum. it is usually asymptomatic until it ruptures, which can be very serious and can result in death
cerebral palsy (CP)
condition characterized by lack of muscle control and partial paralysis, caused by a brain defect or lesion present in birth or shortly after
chronic traumatic encephalopathy (CTE)
progressive degenerative disease of the brain which generally appears years or decades after repeated head trauma. originally diagnosed in boxers (dementia puglilistica), it is not been found in other professional athletes who experienced repeated head trauma, such as football, ice hockey, soccer, wrestling, and basketball players. signs and symptoms include memory loss, aggression, confusion, attention deficits, poor judgement, anxiety, and depression. currently CTE can only be definitively diagnosed after death by brain autopsy, but in the future, diagnostic imaging, chemical biomarkers, and neuropsychological tests may be helpful
dementia
cognitive impairment characterized by loss of intellectual brain function. patients have difficulty in various ways, including difficulty in performing complex tasks, reasoning, learning and retaining new information, orientation, word finishing, and behavior. dementia has several causes and its not considered part of normal aging
epilepsy
condition characterized by recurrent seizures; a general term given to a group of neurological disorders, all characterized by abnormal activity in the brain
multiple sclerosis (MD)
chronic degenerative disease characterized by sclerotic patches along the brain and spinal cord; signs and symptoms fluctuate over the course of the disease; more common symptoms include fatigue, balance and coordination impairments, numbness, and vision problems
parkinson disease (PD)
chronic degenerative disease of the CNS. signs and symptoms include resting tremors of the hand and feet, rigidity, expressionless face, shuffling gait, and eventually dementia. it usually occurs after the age of 50 years (also called parkinsonism)
sciatica
inflammation of the sciatic nerve, causing pain that travels from the thigh through the leg to the foot and toes; can be caused by injury, infection, arthritis, herniated disk, or from prolonged pressure on the nerve from sitting for long periods
shingles
viral disease that affects the peripheral nerves and causes blisters on the skin that follow the course of the affected nerve (also called herpes zoster)
stroke
interruption of blood supply to a region of the brain, depriving nerve cells in the affected area of oxygen and nutrients. the cells cannot perform and may be damaged or die within minutes. the parts of the body controlled by the involved cells will experience dysfunction. speech, movement, memory, and other CNS functions may be affected in varying diseases. ischemic stroke is a result of a blocked blood vessel. hemorrhagic stroke is a result of bleeding (also called cerebrovascular accident [CVA] or brain attack)
subarachnoid hemorrhage (SAH)
bleeding between the pia mater and arachnoid layers of the meninges (subarachnoid space), caused by a ruptures blood vessel (usually a cerebral aneurysm). the patient may experience an intense, sudden headache accompanied by nausea, vomiting, and neck pain. SAH is a critical condition which must be recognized and treated immediately to prevent permanent brain damage or death (a cause of hemorrhagic stroke)
transient ischemic attack (TIA)
sudden deficient supply of blood to the brain lasting a short time. the symptoms may be similar to those of a stroke, but with TIA the symptoms are temporary and the usual outcome is complete recovery. TIAs are often warning signs for eventual occurrence of a stroke
ganglionectomy
excision of a ganglion (also called gangliectomy)