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Mature neuron mitosis
A mature neuron typically cannot undergo mitosis because it does not have centrioles.
Effector function in nervous system
Respond to information.
CNS neurons
Interneurons are neurons located only within the CNS.
Neurolemmocyte function
Increases the propagation rate of a nerve impulse by forming myelin in the PNS.
CNS CSF production
Ependymal cells help produce cerebrospinal fluid (CSF) in the CNS.
Non-CNS cell
Neurolemmocytes are NOT part of the CNS.
Neuron function
Transmits, transfers, and processes nerve impulses.
Reverberating circuit
A neural circuit that is repeatedly stimulated by nerve impulse feedback.
Electrical synapse interaction
Gap junctions facilitate interaction between presynaptic and postsynaptic membranes.
Epineurium description
A thick, dense irregular connective tissue layer enclosing the nerve.
Structural types of neurons
Unipolar, bipolar, and multipolar.
Neuronal structural classification
Determined by the number of processes extending directly from the cell body.
Unipolar neuron
A neuron with a single process that divides into a peripheral and central process, most sensory neurons are unipolar.
Bipolar neuron
A neuron with one axon and one dendrite, found mainly in some special senses.
Multipolar neuron
A neuron with many dendrites and one axon; it is the most common structural type.
Functional types of neurons
Sensory, motor, and interneurons.
Sensory neuron function
Transmits nerve impulses from sensory receptors to the CNS.
Motor neuron function
Transmits nerve impulses from the CNS to muscles or glands.
Interneuron function
Processes information within the CNS and facilitates communication between sensory and motor neurons.
CNS glial cells
Astrocytes, ependymal cells, microglial cells, and oligodendrocytes.
Astrocyte function
Helps form the blood-brain barrier, regulates tissue fluid, provides structural support, replaces damaged neurons, and changes synapse numbers.
Ependymal cell function
Lines the ventricles and central canal and assists in production and circulation of CSF.
Microglial cell function
Defends against pathogens and removes debris through phagocytosis.
Oligodendrocyte function
Myelinates and insulates CNS axons.
PNS glial cells
Satellite cells and neurolemmocytes.
Satellite cell function
Surrounds neuron cell bodies in ganglia and regulates nutrient and waste exchange.
Neurolemmocyte function
Myelinates and insulates PNS axons.
CNS vs PNS myelin
Oligodendrocytes form myelin in the CNS; neurolemmocytes form myelin in the PNS.
PNS axon repair
If the cell body remains intact, the distal portion undergoes Wallerian degeneration, macrophages remove debris, and a regeneration tube forms.
Wallerian degeneration
Breakdown of the distal portion of a severed axon and its surrounding myelin sheath.
Connective tissue coverings of a nerve
Endoneurium, perineurium, and epineurium.
Endoneurium function
Surrounds an individual axon.
Perineurium function
Surrounds a fascicle, or bundle of axons.
Epineurium function
Surrounds the entire nerve.
Difference between neuron, axon, and nerve
A neuron is an individual nervous-system cell; an axon conducts impulses away from the cell body; a nerve is a bundle of many PNS axons.
Types of synaptic communication
Electrical and chemical.
Electrical synapse information transmission
Ions pass directly between cells through gap junctions.
Chemical synapse information transmission
Presynaptic neuron releases a neurotransmitter that binds to receptors on the postsynaptic cell.
Common synapse type in humans
Chemical synapses.
Similarity of converging and parallel-after-discharge circuits
Both involve multiple pathways converging on a common postsynaptic neuron.
Converging vs parallel-after-discharge circuit
Converging circuit receives several inputs that converge, while parallel-after-discharge sends information through several pathways simultaneously before converging.
Basic events of neurulation
Neural plate forms, neural groove develops, neural folds elevate, neural crest cells form and separate, neural folds fuse to form the neural tube.
Multiple sclerosis symptoms
Progressive demyelination and destruction of oligodendrocytes in the CNS, disrupting nerve impulse conduction.
Circulation vs movement and sensation after amputation
Circulation can be restored much more quickly than nerve regeneration, which requires axon regrowth.
Regenerating PNS axon growth speed
About 2–5 mm per day.
Nerve regeneration duration compared to circulation
Regeneration takes longer because nerve axons must physically reconnect with receptors or effectors.
Neuroplasticity after brain trauma
Nervous system remodels existing connections and can sometimes form new connections to compensate for lost function.
Neurogenesis definition
The development of new neurons.
Neurogenesis locations in CNS
Occurs in areas such as the olfactory bulb and hippocampus.
Neuroplasticity vs neurogenesis distinction
Neuroplasticity involves remodeling existing connections, while neurogenesis involves development of new neurons.
Key terms and definitions
Afferent = sensory = toward CNS; Efferent = motor = away from CNS; Interneurons = CNS only.
Myelination differences
Neurolemmocyte = PNS myelin; Oligodendrocyte = CNS myelin.
Glial cells functions
Ependymal = CSF; Microglia = phagocytosis/defense; Astrocytes = BBB/support/synapses.
Connective tissue surrounds the nerve
Endoneurium = axon; Perineurium = fascicle; Epineurium = entire nerve.
Signal transmission types
Saltatory = myelinated + fast; Continuous = unmyelinated + slower.
Synaptic communication types
Electrical synapse = gap junctions; Chemical synapse = neurotransmitter.
Circuit types
Converging = many → one; Diverging = one → many; Reverberating = feedback/repeating; Parallel-after-discharge = multiple pathways.
Neurulation process
Neurulation → neural plate → neural groove/folds → neural tube → CNS.