PTCE: Blood Thinners, Cholesterol, and Diabetes Medications

‘Anticoagulants’ are “Blood Thinners” and aid the …

treatment of blood clots and or/prevention of new clot formation

‘Anticoagulants’ don’t …

actually “thin” the blood

‘Anticoagulants’ interrupt the body’s …

natural clotting process to prevent heart attack and stroke

‘Vitamin K antagonist Anticoagulants’ block …

Vitamin K, which is involved in the clotting process

‘Vitamin K Antagonist Anticoagulants’: inconsistent dietary intake of Vitamin K …

can interfere with effectiveness

‘Vitamin K Antagonist Anticoagulants’: INR Blood Test is required to …

make sure blood clotting is kept at a safe and effective level

the generic name for the, ‘Vitamin K Antagonist Anticoagulants’, is …

Warfarin

the brand name for ‘Warfarin’ is …

Coumadin

DOACs are …

Direct Oral Anticoagulants

DOACs are not affected by …

diet and no INR blood testing required for montioring

DOACs:

Direct Factor Xa Inhibitors

the 2 generic terms for DOACs are …

Apixaban and Rivaroxaban

all DOACs have …

the ‘-aban’ ending

the brand name for ‘Apixaban’ is …

Eliquis

the brand name for ‘Rivaroxaban’ is …

Xarelto

Antiplatelets are …

Platelet Aggregation Inhibitors

Antiplatelets are not …

technically anticoagulants because they don’t affect the clotting process

Antiplatelets work by preventing …

platelets from sticking together to decrease the risk of heart attack or stroke

the 2 generic names of antiplatelets are …

Aspirin and Clopidogrel

the brand name of ‘Aspirin’ is …

Ecotrin

the brand name of ‘Clopidogrel’ is …

Plavix

HMG CoA Reductase Inhibitors reduce …

production of cholesterol made by the liver

the 5 generic names of HMG CoA Reductase Inhibitors are …

Atorvastatin, Simvastatin, Rosuvastatin, Pravastatin, and Lovastatin

the brand name of ‘Atorvastatin’ is …

Lipitor

the brand name of ‘Simvastatin’ is …

Zocor

the brand name of ‘Rosuvastatin’ is …

Crestor

the brand name of ‘Pravastatin’ is …

Pravachol

the brand name of ‘Lovastatin’ is …

Mevacor and Altoprev

Fenofibrate and Omega-3-acid Ethyl Esters reduce …

cholesterol and trigylceride levels

the brand name of ‘Fenofibrate’ is …

Tricor

the brand name of ‘Omega-3-acid Ethyl Esters’ is …

Lovaza

Ezetimibe inhibits …

intestinal absorption of dietary cholesterol

the brand name of ‘Ezetimibe’ is …

Zetia

Sulfonylureas are …

taken by mouth and the oldest diabetes medication available

Sulfonylureas increase …

insulin release from beta cells of the pancreas

the 2 generic medications under Sulfonylureas include:

Glipizide and Glimepiride

the brand name of ‘Glipizide’ is …

Glucotrol

the brand name of ‘Glimepiride’ is …

Amaryl

Biguanides are taken by mouth and reduce the …

amount of sugar produced by the liver, the amount of sugar absorbed in the intestines, AND increase insulin sensitivity

the generic medication under Biguanide is:

Metformin

the brand name of ‘Metformin’ is …

Glucophage

DPP-4 Inhibitors stand for …

Dipeptidyl Peptidase 4 Inhibitors

DPP-4 Inhibitors are taken by mouth and slow the …

inactivation/degradation of GLP-1, an incretin hormone which triggers insulin release to lower blood sugar

the 3 generic medications under DPP-4 are:

Linagliptin, Sitagliptin, and Metformin/Sitagliptin

DPP-4 Inhibitors all have …

the same ending , “-gliptin”

the brand name of ‘Linagliptin’ is …

Tradjenta

the brand name of ‘Sitagliptin’ is …

Januvia

the brand name of ‘Metformin/Sitagliptin’ is …

Janumet

TZDs are …

thiazolidinediones

TZDs are taken by mouth and …

also known as “glitazones”

TZDs increase the …

sensitivity of cells to insulin (decrease insulin resistance)

the generic medication under TZDs is:

Pioglitazone

the brand name of ‘Pioglitazone’ is …

Actos

SGLT-2 Inhibitors are …

sodium-glucose cotransporter-2 inhibitors

SGLT-2 Inhibitors are taken by mouth and …

known as “gliflozins”

SGLT-2 Inhibitors cause …

more glucose to be excreted into the urine instead of reabsorbed into the body

the generic medication under SGLT-2 Inhibitors is:

Canagliflozin

the brand name of ‘Canagliflozin’ is …

Invokana

GLP-1 Analogs are …

Glucagon-like Peptide 1 Agonists

GLP-1 Analogs are injectables that are also known as …

incretin mimetics

GLP-1 Analogs mimic …

incretin hormone GLP-1 produced in GI tract after a meal, causing increased release of insulin from the pancrease

the 2 generic medications under GLP-1 Analogs are:

Liraglutide and Dulagultide

the brand name of ‘Liraglutide’ is …

Victoza

the brand name of ‘Dulagultide’ is …

Trulicity

Insulins are injectables that take …

the place of insulin that is normally produced by the body to move glucose out of the blood into other body tissues where it is used for energy

the different types of Insulins include …

Rapid, Short, Intermediate, and Long Acting

Insulins - Rapid Acting are onset within …

30 minutes and have a duration of 3-5 hours

the 2 generic medications under ‘Insulins - Rapid Acting’ are:

Insulin Lispro and Insulin Aspart

the brand name of ‘Insulin Lispro’ is …

Humalog

the brand name of ‘Insulin Aspart’ is …

Novolog

‘Insulins - Long Acting’ are onset within …

2 hours and have a duration of up to 24 hours (but up to 45 hours with Insulin Degludec)

the 3 generic medications under ‘Insulins - Long Acting’ are …

Insulin Glargine, Insulin Detemir, and Insulin Degludec

the brand name of ‘Insulin Glargine’ is …

Lantus and Basaglar

the brand name of ‘Insulin Detemir’ is …

Levemir

the brand name of ‘Insulin Degludec’ is …

Tresiba