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Integumentary System
Comprises the skin, hair, and nails, serving as the body's outermost protective barrier.
Body Membranes
Thin sheet-like structures that cover and protect, lining body cavities and inner surfaces, with functions including lining, protection, and lubrication.
Connective Tissue Membranes
Composed solely of various connective tissues, such as synovial membranes that line spaces between moving bones and joints.
Synovial Membrane
A smooth and slick membrane that secretes synovial fluid to reduce friction between bones and joints.
Epithelial Membranes
Composed of epithelial tissues and underlying layer of connective tissue.
Serous Membrane
An epithelial membrane that lines body cavities and covers organs, with parietal and visceral portions and serous fluid filling the cavity.
Mucous Membrane
An epithelial membrane that lines body surfaces open to the outside, secreting mucus for protection and lubrication.
Cutaneous Membrane
Refers to the skin, being the largest and most visible organ of the body.
Skin Function
Protection, temperature regulation, sense organ activity, important molecule protection, blood reservoir, and excretion.
Hypodermis/Subcutaneous Tissue
The fatty tissue layer beneath the skin.
Epidermis
The outermost layer of the skin, constantly regenerating and classified into thick skin (palms, fingers, soles) and thin skin (rest of the body).
Dermis
The thickest layer of the skin composed of connective tissue, fibers, and blood vessels, with papillary and reticular layers.
Stratum Corneum
The outermost layer of the epidermis consisting of dead, flat, hardened keratinocytes replaced by keratin.
Stratum Lucidium
Very thin clear band of flattened dead keratinocytes (NOT PRESENT IN THIN SKIN).
Stratum Granulosum
A small layer where the keratinocytes are actively changing by flattening out and harden as granules begin "armor plating" the cells.
Stratum Spinosum
Keratinocytes in this layer appear spiny as they begin to shrink.
Stratum Basale
The deepest epidermal layer attached to the dermis, consisting of rapidly dividing keratinocytes and melanocytes producing melanin.
Langerhans Cells
Cells present in the stratum spinosum of the epidermis that help activate the immune system.
Melanocytes
Cells in the stratum basale that produce melanin, the pigment responsible for skin color.
Merkel Cells
Function as touch receptors (with merkel discs in dermis).
Epidermis Physiology
The constant sloughing off and replacement of epidermal cells, with cell production in the stratum basale and complete epidermal replacement every 25-45 days.
Melanin
A pigment produced by melanocytes packaged in melanosomes in the skin's basal layer, providing protection against UV rays and determining skin color.
Papillary Layer
The thin, superficial layer of the dermis containing areolar connective tissue, capillaries, and sensory neurons.
Elastin
A type of fiber present in the dermis providing elasticity to the skin.
Collagen
A type of fiber in the dermis contributing to the skin's strength.
Dermal Papillae
Fingerlike projections of the papillary layer of dermis
Epidermal Ridges
Areas of the epidermis that dip down into the dermal papillae
Reticular Layer
Deepest and thickest skin layer containing dense irregular connective tissue, arteries, veins, and glands
Cleavage lines
Deep creases where collagen and elastic fibers are arranged in parallel bundles
Light Touch
Meissner's Corpuscles, Merkel Discs, and Root Hair Plexus.
Deep Pressure
Pacinian Corpuscles and Ruffini's Corpuscles.
Free nerve endings
Sensory receptors for pain and temperature.
Krause End Bulbs
Sensory receptors for temperature.
Sudoriferous (sweat) glands
Glands that originate in the dermis, excrete sweat, and are found throughout the skin except nipples and some genital areas
Eccrine Sweat Glands
Most common sweat glands that produce watery sweat released through pores
Apocrine Sweat Glands
Sweat glands found in axillary and genital regions, larger than eccrine glands, excreting sweat, fatty substances, and proteins into hair follicles
Sebaceous (oil) glands
Glands found all over the body except palms and soles, secreting sebum to lubricate and protect the skin
Sebum
Oily substance of lipids and cell fragments secreted by sebaceous glands. It softens and lubricates the hair and surrounding skin and is antibacterial.
Hair (Pili)
A modified portion of the epidermis where cells fill with hard keratin and grow out in pillars instead of the flat sheets of the stratum corneum.
Hair follicle
Modified fold of the epidermis into the dermis where hair grows from
Root Hair Plexus
A touch receptor wrapping the hair bulb, or the deep end of the follicle.
Papilla
Dermal tissue that protrudes into the hair supplying the hair with blood vessels.
Hair Matrix
Actively dividing area that produces the hair shaft.
Arrector pili muscle
Smooth muscle cells that raise the hair when cold or scared
Hair shaft
Consists of medulla, cortex, and cuticle layers of keratinized cells
Anagen Growth Phase
Lasting weeks to years depending on location.
Catagen Regressive Phase
When the hair matrix cells die.
Telogen Resting Phase
Lasts one to three months.
Nail Matrix
Area of epidermis producing new nail cells
Lunula
White crescent visible on the nail above the matrix
Hyponychium
Area under the free edge of the nail
Nail Bed
Deeper layers of epidermis underneath the nail body which contains blood vessels.
Nail Root
Area of nail embedded in the matrix.
Eponychium
Cuticle; area where the skin folds in on itself.