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Fluid & Electrolyte Balance
Foundation for understanding renal, cardiac, endocrine functions.
Core Electrolytes
Key electrolytes to master: Potassium (K⁺), Sodium (Na⁺), Calcium (Ca²⁺), Magnesium (Mg²⁺).
Functions of Water
Transport medium, temperature regulation, acid-base balance, enzymatic digestion.
Osmosis
Water moves from low to high solute concentration.
Semipermeable Membrane
Allows selective passage of substances; found in cell membranes.
Hypervolemia
Fluid volume excess; can occur due to CHF, renal failure, excess IV fluids.
Euvolemia
Normal fluid volume status.
ADH (Antidiuretic Hormone)
Hormone that promotes water reabsorption in kidneys.
Hypothalamus
Detects increased osmolality and triggers thirst.
Atrial Natriuretic Peptides (ANP)
Hormones released by atria that reduce blood volume by promoting Na⁺ excretion.
Age-Related Sensitivities
Elderly and infants have specific fluid imbalances concerns.
Dilutional Hyponatremia
Low sodium caused by fluid overload.
Active Transport
Energy-requiring movement of molecules against a gradient.
Nephrotoxic Substances
Drugs/substances that can cause kidney damage.
Urinary Incontinence Types
Stress, urge, mixed, overflow, functional, neurologic.
Cystitis
Inflammation of the bladder typically caused by bacterial infection.
Glomerulonephritis
Inflammation of the kidney’s filtering units, often following infections.
Acute Kidney Injury (AKI)
Sudden decline in kidney function, seen as increased creatinine and decreased GFR.
Electrolytes
Charged molecules that facilitate nerve and muscle function.
Osmolality
Measure of solute concentration in blood or urine.
Daily Fluid Intake Requirement
Minimum daily fluid intake is typically 2-3 liters.
Urine Output Normal Range
Normal urine output is approximately 60 mL/hr.