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Where are MHC (HLA) I molecules found?
on ALL NUCLEATED CELLS
What is the main function of MHC (HLA) I molecules?
Present antigens to CD8+ T cells
What types of cells do MHC (HLA) I molecules bind?
endogenous intracellular pathogens
What types of cells do MHC (HLA) II molecules bind?
extracellular (exogenous) antigens
What is the main function of MHC (HLA) II molecules?
Present antigens to CD4+ T cells
What is the main function of macrophages?
Present antigens to T cells via MHC II
What cell is the most effective APC?
Dendritic cells