Chemistry Addition Reactions

Hydrohalogenation

H-X

Adding H and Halogen

• Markovnikov

• Syn and Anti

Acid Catalyzed Hydration

H3O+

adding H and OH

• Markovnikov

• Syn and Anti

Oxymercuration-Demercuration

1.) Hg (OAC)2, H2O

2.) NaBH4

alkenes into alcohols

• Markovnikov addition

• OH on more, Hg on Less

Hydroboration - Oxidation

1.) BH3 THF

2.) H2O2, NaOH

adding H and OH

• Anti-Markovnikov

• syn

Catalytic Hydrogenation

1.) H2, Pt

adding H and H

• Not relevant

• syn

Halogenation

Br2

adds Br and Br

• not relevant

• anti

Halohydrin Formation

1.) Br2, H2O

adds Br and OH

• OH on more sub

• anti

Anti-Dihydroxylation

1.) MCPBA

2.) H3O+

adds OH and OH

• not relevant

• anti

Syn - Dihydroxylation

1.) OsO4

2.)H2Os

adds OH and OH

• not relevant

• syn

Oxidative cleavage/ozonolysis

1) O3

2) DMS (CH3)2S, or (Zn/HOAC) or (Me2S)

split double bonds