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What is the function of the nervous system?
Detects and responds to changes inside and outside the body
What system works together with the nervous system?
Endocrine system
What are the three main components of the nervous system?
Brain
Spinal cord
Peripheral nerves
What are the two parts of the nervous system?
Central nervous system
Peripheral nervous system
What are the components of the central nervous system?
Brain and spinal cord
What is the component of the peripheral nervous system?
Peripheral nerves
What are the two types of nervous tissue?
Neurones
Neuroglia
What are the five components of the neurones?
Cell body
Axon
Dendrites
Axon terminal
Terminal boutons
What is the function of neurones?
Generate and transmit electrical impulses called action potentials
What are the two types of stimuli that initiate action potentials?
External and internal
Where does electrical transmission of nerve signals occur?
Travelling down the nerve axon
Where does chemical transmission of nerve signals occur?
Between nerve cells across synapses
What structure makes up the grey matter of the nervous system and where are they found?
Cell bodies
Periphery of brain and in centre of spinal cord
What are groups of cell bodies called?
Nuclei in the CNS
Ganglia in the PNS
What are the two different names for groups of axons and where are they found?
Tracts at the periphery of the spinal cord
Nerve fibres outside the CNS
What are dendrites?
Numerous, short, branching extensions of the cell body that recieve and transmit action potentials
What is the tapered area of the cell body called?
Axon hillick
What is the outer membrane of the axon called?
Axolemma
What are the two types of neurones?
Myelinated
Unmyelinated
What are unique characteristics of myelinated neurones?
Myelinated sheath made up of layers of Schwann cells wrapped around the axon
What is myelin?
Fatty substance between layers of Schwann cell plasma membrane
What is the neurilemma?
Outermost layer of Schwann cell plasma membrane
What are nodes of Ranvier?
Tiny areas of exposed axolemma
What are the three structural classifications of neurones?
Multipolar
Bipolar
Unipolar
How do you identify a multipolar neurone and where are they found?
Several dendrites and one axon
Brain and spinal cord
How do you identify bipolar neurones and where are they found?
One main dendrites and one axon
Found in retina, inner ear and olfactory area
How do you identify a unipolar neurone?
Dendrites and axon fused together to from a continuous process
What is a synapse?
The point an action potential passes from one neurone to
What is the synaptic cleft?
Space between the terminal boutons and dendrites
What do vesicle in the synaptic knobs contain?
Neurotransmitter
What are nerves?
Collection of neurones bound together by connective tissue
What are the three coverings of protective connective tissue in neurone bundles?
Endoneurium
Perineurium
Epineurium
What are the three functional classifications of neurones?
Sensory
Motor
Interneurones
What is the function of sensory nerves?
Carry information from the body to the spinal cord
What is the function of motor neurones?
Convey action potentials to effectors through cranial or spinal nerves
What are the two types of motor neurones?
Somatic nerves
Autonomic nerves
What is the function of somatic nerves?
Voluntary and reflex of skeletal muscle contraction
What are the two types of autonomic nerves and what are their functions?
Sympathetic and parasympathetic
Involuntary functions
What is the function of inter neurons?
Process sensory information and activate motor neurones
What are tracts?
Seperate groups of sensory and motor neurones in the spinal cord
What are mixed nerves?
Sensory and motor nerves enclosed in the same connective tissue sheath outside the spinal cord
What are neuroglia?
Non excitable glial cells supporting the neurones of the CNS
What are the four types of neuroglia?
Astrocytes
Oligodendrocytes
Ependymal cells
Microglia
What is the function of astrocytes?
Form a sleeve around blood vessels, contributing to the blood brain barrier
What is the function of oligodendrocytes and where are they found?
Form and maintain myelin in the CNS
Multiply around degenerating neurones
Cluster round grey matter and along myelinated nerve fibres
What is the function of ependymal cells and where are they found?
Assist the flow of CSF through cavities in the brain
Ciliated cells in epithelial lining of ventricles and central canal
What is the origin of microglia cells?
Derived from monocytes migrating from the blood into the nervous system
Found in the brain
What is the function of microglia cells?
Enlarge and become phagocytise when inflammation and cell damage migrate to the brain
What are the meninges and where are they found?
Three layers of protective tissue
between the skull and brain
between the vertebral foramina and spinal cord
What are the three meninges?
Dura matter
Arachnoid matter
Pita matter
What are the two spaces associated with the meninges?
Subdural space
Subarachnoid space
What is the subdural space?
Potential space between dural and arachnoid maters
Contains small amount of serous fluid
What is the subarachnoid space?
Potential space between the arachnoid and pia maters
Contains cerebrospinal fluid
What is the arachnoid mater?
Fibrous membrane between dura mater and pia mater
Continues down the spinal cord and merges with the dura at the second sacral vertebra
What is the pia mater?
Connective tissue layer with many blood vessels contouring to the brain
Continues down, surrounding the spinal cord and fusing with the periosteum of the coccyx
What is the dura mater?
Loose covering around the spinal cord continuing from the brains inner dura layer
starting at the foramen magnum
extending into the second sacral vertebrae
What are the four ventricles of the brain?
Right and left lateral ventricle
Third ventricle
Fourth ventricle
Where is cerebrospinal fluid made?
In brain ventricles by choroid plexuses
What are choroid plexuses?
Areas full of blood vessels lined with ependymal cells
What is the pathway of cerebrospinal fluid flow?
Through the brain and spinal cord
Absorbed back into bloodstream through arachnoid villa
Arachnoid villa stick out into venous sinuses
What factor determines CSF flow into the blood?
Pressure differences
What are the six main components of the brain?
Cerebrum
Thalamus
Hypothalamus
Midbrain
Pons
Medulla oblongata
What is the location of the cerebrum?
Front and middle part of the skull
What is the structure of the cerebrum?
Split into right and left hemispheres each with a lateral vesicle
What structure separates the left and right hemispheres of the cerebrum?
Longitudinal fissure
What structure connects the left and right hemispheres of of fhe cerebrum?
Corpus callosum (bundle of nerves)
What is the cerebral cortex?
Outer layer of the cerebrum
What are gyri?
Folds in the surface of the cerebrum
What are sulci?
Grooves in the surface of the cerebrum
What are the four lobes of each cerebral hemisphere?
Frontal
Parietal
Temporal
Occipital
What are the three sulci of the cerebral hemispheres?
Central sulci
Lateral sulci
Parieto occipital sulci
Where is the thalamus found?
One on each side of the third ventricle
What is the function of the thalamus?
Recieves signals from skin, organs and sense organs to detect basic sensations
Relay station
Where is the hypothalamus found?
Below and in front of the thalamus
Above the pituitary gland
What links the hypothalamus to the posterior lobe of the pituitary gland?
Nerve fibres
What links the hypothalamus to the anterior lobe of the pituitary gland?
Complex blood vessel system
Where are the pons located?
In front of the cerebellum
Below the midbrain
Above the medulla oblongata
What is the function of the pons?
Connects cerebellum and links brain to spinal cord
Helps process signals for some cranial nerves
Where is the medulla oblongata located?
Most inferior region of brain stem
Above the foramen magnum
Continuous with spinal cord
Where is the spinal cord located?
Vertebral canal
Extends from upper border of atlas
Terminates at lower border of first lumbar vertebra
How many cervical nerves are there?
8
How many thoracic nerves are there?
12
How many lumbar nerves are there?
5
How many sacral nerves are there?
5
How many coccygeal nerves are there?
1