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Neurotransmitters
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Last updated 8:16 PM on 9/21/22
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20 Terms
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Agonist
________: a drug that mimics or increases the effects of a neurotransmitter (many antidepressants (blocks serotonin reuptake))
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Metabotropic Receptors
________: no ion channel (still a binding place for neurotransmitters (G- Protein attached to the intracellular side)
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Antagonist
________: drug that blocks the effects of a neurotransmitter (many antipsychotics (block dopamine receptors therefore dopamine antagonists))
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Ionotropic receptors
pore opens up and ions go through
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o Metabotropic Receptors
no ion channel (still a binding place for neurotransmitters (G-Protein attached to the intracellular side)
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Most common Excitatory Neurotransmitter
Glutamate (memory formation)
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Most Common Inhibitory Neurotransmitter
Gaba (gaba receptor targeted in anxiety treatment)
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Agonist
a drug that mimics or increases the effects of a neurotransmitter (many antidepressants (blocks serotonin reuptake))
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Antagonist
drug that blocks the effects of a neurotransmitter (many antipsychotics (block dopamine receptors therefore dopamine antagonists))
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Within Neurons
Where are neurotransmitters made?
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Midbrain, Raphe Nuclei
What part of the brain nuclei is responsible for serotonin?
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Substantia Nigra or Ventral Tegmental Area
What part of the brain nuclei is responsible for dopamine?
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basal forebrain
What part of the brain nuclei is responsible for acetylcholine?
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phenylalanine
Initial Precussors for Dopamine, dorepinephrine, and epineephrine?
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Choline
Initial Precussors for acetylcholine?
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Trytophan
Initial Precussors for Seratonin?
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Catecholamines
Dompamine, Norepinephrine, Epinephrine
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Monoamines
Dompamine, Serotonin, Norepinephrine, Epinephrine
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Absorption by Glia, Enzymatic Degradations , and Reuptake (by presynaptic terminal (transporter protein))
What are the 3 ways to remove a neurotransmitter from a synapse?
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Increases or decreases neurotransmitter synthesis
Increases or decreases neurotransmitter release
Binds to and activate a receptor (receptor agonist)
How psychotropic drugs affect brain activity?