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Which of the following statements about RNA polymerase is false?
It synthesizes mRNA in a 3' to-5' direction, reading the DNA strand 5' to 3'.
The process of gene expression involves two steps in which _______ is transcribed into _______, which is (are) translated into _______.
DNA;RNA;Protein
The enzyme that catalyzes the synthesis of RNA is
RNA polymerase
Transcription is the process by which
an RNA molecule is synthesized from a DNA template.
Which statement about the flow of genetic information is true?
DNA encodes information that is translated into RNA, and RNA encodes information that is translated into proteins.
The _______ strand of DNA is transcribed to produce an RNA strand by DNA bases pairing with _______ bases of RNA.
template; complementary
During initiation, the sequence of DNA to which RNA polymerase binds most tightly is the
promoter
RNA polymerase uses the _______ DNA template to synthesize a _______ mRNA.
3′-to-5′; 5′-to-3′
A transcription factor is _______ that assists transcription by binding to _______.
a protein; the promoter
Promoters are made of
nucleic acids.
Termination of transcription involves a
terminator sequence.
If the transcribed mRNA is 5′-AUGCUCGUGACGAUU-3′, what was the template strand of DNA?
3′-TACGAGCACTGCTAA-5′
The three-dimensional structure of tRNA is maintained by
Hydrogen bonds
The anticodon 3′-AUC-5′ would pair with the codon
5′-UAG-3′.
Ribosomes are a collection of _______ that are needed for _______.
proteins and small RNAs; translation
In what order does a charged tRNA molecule move between the three sites on the ribosome?
A, P, E
During translation initiation, the first site occupied by a charged tRNA is the _______ site.
A
During translation, the formation of a peptide bond between an amino acid at the P site and an amino acid at the A site is catalyzed by
the large ribosomal subunit.
Stop codons terminate translation by
binding a protein release factor, causing hydrolysis of the bond between the polypeptide chain and the tRNA.
What is a ribozyme?
Any RNA with catalytic ability
In protein synthesis, the endoplasmic reticulum
is the site of translation of membrane-bound and exported proteins.
The addition of sugar residues to the protein after translation is called
glycosylation.
The offspring resulting from asexual reproduction are called _______ and are genetically _______ their parent.
clones; identical or virtually identical to
The haploid number of chromosomes is _______ the diploid number.
half
Diploid cells of the fruit fly Drosophila have ten chromosomes. How many chromosomes does a Drosophila gamete have?
5
Pairing of homologous chromosomes occurs
meiosis I only
The number of chromosomes in a cell is reduced by half during
meiosis I
Sexual reproduction increases genetic variability through
crossing over, independent assortment, and random fertilization.
Which statement about meiosis and mitosis is true?
The products of meiosis can be different from one another, while the products of mitosis are all the same (except for rare mutations).
During meiosis, the sister chromatids separate during
anaphase II
At the end of the first meiotic division, each chromosome consists of
two chromatids.
The exchange of genetic material between chromatids on homologous chromosomes occurs during
prophase I.
Different forms of a gene are called
alleles
At a certain locus of the human genome, 200 different alleles exist in the population. Each person has at most _______ allele(s).
2
In mice, short hair is dominant to long hair. If a short-haired individual is crossed with a long-haired individual and both long- and short-haired offspring result, one can conclude that
the short-haired parent is heterozygous.
Classical albinism results from a recessive allele. What is the expected ratio for the progeny when a normally pigmented male with an albino father has children with an albino woman?
50% normal, 50% albino
Separation of the alleles of a single gene into different gametes is called
segregation
Mendel's law of segregation results from the processes that occur during
meiosis I
Segregation of alleles occurs during meiotic cell division. During which phase of meiotic cell division are different alleles of the same gene segregated into two daughter cells?
cytokinesis I