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What is a endocrine gland
A ductless gland that secretes hormones directly into the blood stream to regulate body processes
List the major endocrine glands
Pituitary, hypothalamus, thyroid, parathyroid’s, adrenal gland, pancreas, thymus, and gonads (testes and ovaries)
What is a hormone
A chemical messenger secreted by endocrine glands that travels through the blood to target specific cells
Name some processes regulated by hormones
Growth, metabolism, reproduction, blood sugar regulation, stress response, and calcium balance
How is the endocrine system similar to the nervous system
Both coordinate and regulate body functions and maintain homeostasis, though the endocrine system acts more slowly and uses chemical messengers (hormones)
How are hormones classified by structure
As amino acid based hormones or steroid hormones
What is a target cell
A cell that has receptors for a specific hormone and responds to its signal
What are the three mechanism that control hormone secretion
Humoral - blood levels of ions and nutrients
Neural - nerve stimulation
Hormonal - hormone triggers another hormone
Where is the pituitary gland located
At the base of the brain, in the sella turcica of the sphenoid bone
Name the hormones secreted by the anterior pituitary and their targets
GH- bones and muscles
TSH- thyroid
ACTH- adrenal cortex
FSH and LH- gonads
PRL- mammary glands
MSH- melanocytes
Name hormones secreted by the posterior pituitary and their targets
ADH- kidneys (water reabsorption)
Oxytocin- uterus (contractions) and mammary glands (milk ejection)
How does the hypothalamus control the anterior pituitary
Through releasing and inhibiting hormones via the hypophyseal portal system
What is the hypophyseal system
A network of blood vessels that carry’s hormones from the hypothalamus to the anterior pituitary
What is the difference between releasing and inhibiting hormones
releasing hormones stimulate hormone release, inhibiting hormones prevent it
Describe the path of releasing hormones in the pituitary
Releasing hormones travel from the hypothalamus through the hypophyseal portal system to the anterior pituitary
Describe the location and hormones of the thyroid and parathyroid glands
Thyroid (neck) T3 T4 calcitonin
Parathyroid’s (posterior thyroid) PTH
Describe the adrenal gland structure and hormones
Cortex- aldosterone, cortisol, androgens
Medulla- epinephrine and norepinephrine
What hormones does the pineal gland secrete and what is it’s function
Melatonin, regulates sleep wake cycles
What does the pancreas secrete and what are the effects
Insulin- lowers blood sugar
Glucagon- raises blood sugar
What does the thymus secrete and what is it’s function
Thymosisns, help secrete the maturation of T cells (immune system)
What hormones does the gonads secrete
Testes- testosterone
Ovaries- estrogen and progesterone
What is the difference between hypo-secretion and hyper-secretion
Hypo- to little hormone
Hyper- to much hormone
Each causes specific disorders
What is diabetes mellitus
A disorder in which insulin is deficient or ineffective, leading to high blood sugar levels
How do endocrine glands develop embryologically
From ectoderm, mesoderm, and endoderm layers depending on the gland
What changes occur in the endocrine system with aging
Decreased hormone levels, reduced sensitivity, and slower metabolic stress response