pathology II EXAM 1

fibrous dysplasia

bone condition characterized by replacement of normal bone by fibrous connective tissue intermixed with abnormal bone

mccune albright syndrome

polyostotic fibrous dysplasia, cafe au lait spots and endocrinopathies indicate?

polyostotic

fibrous dysplasia that affects multiple bones

fibrous dysplasia

lesion with GROUND GLASS appearance diagnosis?

low recurrence rate

All of the following are true for fibrous dysplasia EXCEPT:

single or multiple

occurs in teenagers and young adults

low recurrence rate

expansile lesion

polystotic

type of FIBROUS DYSPLASIA that occurs in children

neurofibromatosis 1

SMALLER cafe au lait spots that CROSS MIDLINE

mccune albright syndrome

LARGER cafe au lait spots that DO NOT cross midline

cenento osseous dysplasia (COD)

most common fibro-osseous lesion

periapical cemento osseous dysplasia (COD)

history: middle-aged African American woman, teeth are vital and asymptomatic, LOSS of LAMINA DURA

focal COD (cemento osseous dysplasia)

history: middle-aged Africa-American woman, tooth is vital and asymptomatic

hypercementosis

diagnosis?

florid COD (cemento osseous dysplasia)

typically found in middle-aged African American women, vital teeth and asymptomatic radiographic findings.

follow up

trreatment of COD (cemento osseous dysplasia)

cementoblastoma

benign neoplasm of cementum, VITAL teeth but PAINFUL

COD (cemento osseous dysplasia)

location is ALWAYS at apex of tooth

osteogenesis imperfecta

genetic disorder of fragile bones due to defective type 1 collagen synthesis, leading to frequent fractures.

osteogenesis imperfecta

presents with low bone density (OSTEOPENIA) and BLUE SCLERA

osteogenesis imperfecta

blue/grey teeth with OBLITERATED PULP CHAMBER (shell teeth)

increase in bone density (bone density decreases in OI)

which of the follwing is FALSE for osteogenesis imperfecta:

AD most common inheritance

affects bone, teeth, and sclera

increase in bone density

affects type 1 collagen

Osteopetrosis/Albers-schonberg/marble bone

decreased osteoclatic activity leading to INCREASED BONE DENSITY

decreased bone density

All of the following are features of Alber-schonberg disease (osteopetrosis) EXCEPT:

multiple fracture

decreased bone density

blindness

deafness

Cleidocranial dysplasia

AD disorder associated with prolonged rention of teeth and SUPERNUMERARY TEETH

cleidocranial dysplasia

diagnosis

hypodontia

which of the following is FALSE regarrding cleidocranial dysplasia:

AD inheritance

affects clavicles and skull

hypodontia

prolonged teeth retention

cherubism

PAINLESS BILATERAL posterior mandible ENLARGEMENT in children

cherubism (mixed dentition with multilocular radiolucencies)

diagnosis?

supernumerary teeth

which feature is NOT a feature of CHERUBISM:

billateral enlarged mandible

painless

supernumerary teeth

occurs in children

paget disease of bone/ osteitis deformans

metabolic disease characterized by abnormal resorption and deposition causing INCREASE in SKULL SIZE (dentures no longer fit)

paget disease

generalized increased in bone most commonly in maxilla

paget disease

COTTON WOOL appearance, loss of lamina dura, and hypercementosis

paget disease

high serum alkaline phosphatase levels with NORMAL calcium and phosphorus levels

osteosarcoma

concern with paget disease

multilocular

All of the following are radiographic features of paget disease EXCEPT:

loss of lamina dura

cotton wool appearance

hypercementosis

multilocular

condensing osteitis is a type of osteomyelitis

odontogenic keratocyst

which of the foolowing clinic features is not part of mccune albright syndrome?

osteitis deformans (Pagets)

generalized hypercementosis is associated with:

periapical cyst

periapical cemento-osseous dysplasia

diagnosis?

ground glass

what is the description of this radiographic feature?

osteogenesis imperfecta

what condition is associated with this clinical image?

paget disease

diagnosis?

osteopetrosis

diagnosis?

mccune albright syndrome

diagnosis?

osteogenesis imperfecta

what is the condition?

hypercementosis

diagnosis?

osteoma

benign bone tumor in MANDIBULAR BODY, associated with gardners syndrome

gardner syndrome

what. syndrome is associated with multiple osteoma

osteoma

well circumscribed radiopaque lesion in angle of mandible, diagnosis?

colorectal cancer

major risk with GARDNER SYNDROME

gardner syndrome (multiple osteoma)

what is the diagnsis?

small, slow-growing, and found in skull

Which of the following is CORRECT for osteoma

cafe au lait spots

All of the following are features of Gardner syndrome EXCEPT:

osteoblastoma

benign bone tumor larger than 2-4 cm, causes nocturnal PAIN not relieved by aspirin

relieved by aspirin

Which of the following statements about OSTEOBLASTOMA is FALSE

cementoblastoma

benign odontogenic neoplasm of cementoblasts

cementoblastoma

diagnosis? radiopaque lesion with radiolucent border in molar area, can be symptomatic

radiolucent mass

which of the following is INCORRECT for cementoblastoma

osteosarcoma

MALIGNANT bone neoplasm, most commonly found in distal femur and proximal tibia

osteosarcoma

ill defined MOTH EATEN appearance, and widening of PDL space

osteosarcoma

presents with SUNBURST appearance

osteosarcoma

diagnosis?

radiolucent halo rim

which of the following feature is NOT typically associated with osteosarcoma

chondrosarcoma

malignant bone tumor of cartilage

surgery (resistant to chemo and radiation)

ONLY treatment for chondrosarcoma

Ewing sarcoma

highly lethal primary malignant tumor of bone

ewing sarcoma

irregular defined borders, and can present with onion skin or sunray appearance

post radiaiton bone sarcoma

sarcoma in bone that has been previosly subjected to radiation therapy

breast

most common origin of metastasis in jaws

more common location is gingiva

which of the following statements about METASTATIC DISEASE to the head and neck is FALSE

focal osteoporotic bone marrow defect

area of hematopoitic marrow that produces radiolucency

idiopathic osteosclerosis

well defined dense bone associated with VITAL tooth and is often asymptomatic

condensing osteitis

diagnosis?

condensing osteitis

diagnosis?

central giant cell granuloma

radiolucent, well defined, non corticated lesion in anterior jaw

central giant cell granuloma

occurs before 30 years old and crosses midline, diagnosis?

cementoblastoma

which of the following is NOT a multilocular lesion?

ewing sarcoma

Onion skin is associated with:

no expansion

which of the following is FALSE regarding ossifying firbroma

condensing osteitis

which of the following is NOT a NEOPLASM

focal osteroporotic bone marrow defect

all of the following are RADIOPAQUE lesions EXCEPT

multilocular

which of the following is TRUE for focal osteoporotic bone marrow defect

cementoblastoma (first molar and radiolucent rim)

what is the diagnosis?

condensing osteitis

what is the diagnosis?

gardner syndrome

what is the condition associated with multiple radiopaque lesions at the angle of the mandible

idiopathic osteosclerosis

what is the diagnosis

multilocular

how would you describe this lesion

osteoporotic bone marrow defect

diagnosis?

periapical cemento-osseous dysplasia (COD)

diagnosis?

sunburst

how would you describe this lesion

focal cemento-osseous dysplasia (COD)

what is the diagnosis?

chondrosarcoma

diagnosis?

periapical (radicular) , residual, and buccal bifurcation

types of INFLAMMATORY CYSTS

stafne bone cyst/ lingual mandibular gland depression

developmental defect BELOW mandibular canal near angle of mandible, pseudocyst

trraumatic bone cyst

scalloping radiolucency around VITAL teeth, EMPTY CAVITY

traumatic bone cyst

teeth are vital and asymptomatic, diagnosis?

aneurysmal bone cyst

pseudocyst, blood filled spaces, characterized by rapid enlarging swelling in posterior mandile

traumatic bone cyst

which of the following exibits an EMPTY CAVITY

nasopalatine duct cyst

most common NONODONTOGENIC CYST of the oral cavity

nasopalatine duct cyst

diagnosis?