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What is Osteogenic cells?
stem cells that differentiate into osteoblasts
What is Osteoblasts?
immature cells that actively produce and
secrete bone
What is Osteocytes?
mature cells that maintain bone
Whatr is Osteoclasts?
Responsible for resorption (breakdown) of bone
What does osteoclastrs secrete?
Secrete hydrochloric acid and lysosomal enzymes
What are oseteoclasts derived from?
line of white blood cells
What is compact bone?
Dense outer layer of bone
What are compact bones organized of?
osteons
What is spongy bone?
Found within flat bones and within the epiphyses (ends) of long bones
Where is spongy bone found?
flat bones and withing the epiphyses of long bones
What is the Epiphyses?
ends of bones
What is spongy bone organized up of?
trabeculae
what is trabeculae made up of?
little “beams” of bone
Where is red bone marrow found?
within the trabeculae of spongy bone
What is the reason that there is lysosomal enzymes and hydrochloric acid in the osteoclasts?
whenever there is too much calcium
What is another name for spongy bone?
cancellous
What is yellow bone marrow?
fat
Where is yellow bone marrow found?
open spaces called medullary cavities in long bone
True or False: All bones have spongy bone but not all bones have compact bone
false
True or False: All bones have compact bone but not all have spongy bone
True
What is the periostrium?
connective tissue that surrounds all of out bones that allows for other connective tissues to be intertwined
What is a safe place for vasculture, vessles and nerves to be at?
periostrium
What are some examples that consist spongy bones?
skulls, irregular bones, and short bones
What is Osteoporosis?
characterized by low bone mass, bone reabsorption outpaces bone deposition, occurs in most of women after menopause (secretion of estrogens helps maintain bone density)
Where does osteoporosis occur more likely in?
women after menopause
What is rickets?
weakened and bowed legs, malformation of the head and ribs (caused by dietary Vit D
and calcium phosphate deficiency).
What is rickets in adults?
osteomalacia
Where does rickets occur most likely in?
rickets
What is Osteosarcoma?
a form of bone cancer
What are type of horomes does cancer turmos secrete that normal tissues would not do?
Parathyroid hormone
What is paraneoplastic syndrome?
the body to release hormones or triggers the immune system to mistakenly attack healthy tissues and organs
What happens when a malignant tummor secretes PTH?
bones become very thin and break easily.
The increase in ____ in the blood can also cause problems like osteoporosis
Ca+2
What are the paired bones of the skull?
Temporal bones, Parietal bones
What are the eight large bones in the skull?
Frontal bone, Occipital bone, Sphenoid bone, Ethmoid bone, Temporal bones, Parietal bones
What are the paired facial bones?
Maxillae, Zygomatic bones, Nasal bones, Lacrimal bones, Palatine bones, Inferior nasal conchae
What are the unpaired facial bones?
Mandible and vomer
What is a Cleft palate?
failure of fusion of the lateral palatine processes, the nasal septum, and/or
median palatine process; surgery required
Is surgery required to fix a cleft palate?
yes
What are the causes of a cleft palate?
increased steroid exposure in fetal life augments the chance of cleft lip/
palate
Which type of palate is more common, Anterior cleft palate or Posterior cleft palate?
Posterior cleft palate
What is a Cleft Lip?
Failure of fusion of the maxillary and medial nasal processes leading to persistent
labial groove (uni- and bilateral), surgery required
Is surgery required for a cleft lip?
yes
What is the most common type of cleft lip?
Unilateral Cleft Lip
What is the most common congenital malformation of the head?
Uniform Cleft lip
What makes up the hynoid bone?
Body (anterior)
Greater horns (laterally)
Lesser horns (upwards)
What are the three functions of the nervous system?
Sensory receptors monitor changes inside and outside the
body, 2. Processes and interprets sensory input, 3. Dictates a response by activating effector organs
What is stimulus?
changes detected inside or outside the body
What is sensory input?
information gathered by receptors
What is Integration?
term for interpreting input
What is Motor output?
is the response
What is Central nervous system (CNS)?
Composed of the brain and spinal cord
What is Peripheral nervous system (PN?
Consists of nerves extending from brain and spinal cord, Peripheral nerves link all regions of the body to the CNS
What links all regions of the body to the CNS?
Peripheral nerves
What are some examples that are in the PNS?
Cranial nerves, Spinal nerves, Nerons and neuroglial cells
What is Sensory (afferent) signals carried by?
nerve fibers of PNS to the CNS
What are sensory or afferent signals?
electrical and chemical messages that travel from the body's sensory receptors toward the central nervous system ( smell, touch, sight, pain)
What are motor (efferent) signals?
nerve impulses that travel away from the central nervous system (the brain and spinal cord towards the muscles
What are motor (efferent) signals carried by?
Innervate muscles and glands
What is the difference between efferent and afferent signals?
efferent signals carry command signals away from the brain and spinal cord, unlike sensory (afferent) signals that carry information toward the brain.
What is the Somatic nervous system?
Somatic motor (voluntary), Conducts impulses from the CNS to skeletal muscles
What is the Autonomic nervous system (ANS)?
Visceral motor (involuntary), Conducts impulses from the CNS to cardiac muscles, smooth muscles, and glands
What are the two divisions of the ANS?
Sympathetic and Parasympathetic
What are the two divisions of the Motor (efferent) division?
ANS and somatic nervous system
What is the sympathetic division?
Mobilizes body systems during activity
What is the parasympethetic?
Conserves energy, Promotes house- keeping functions during rest
What are the three different types of neurons?
Sensory neurons, Motor neurons, interneurons
What are Interneurons?
most are multipolar, Lie between motor and sensory neurons, Confined to the CNS
What are Multipolar nueron?
possess more than two processes
What are bipolar nueron?
possess two processes
What are unipolar nueron?
possess one short, single process
Where would you most likely find unipolar nuerons?
PNS
Where would you most likely find multipolar nuerons?
CNS
What are Astrocytes?
the most abundant glial cell type
Where would you find bipolar nuerons?
rare, found in sensory organs, like eye, ear, etc.
What are some function of astrocytes?
Sense when neurons release glutamate
• Extract blood sugar from capillaries for energy
• Take up and release ions to control environment around neurons
• Involved in synapse formation in developing neural tissue
• Produce molecules necessary for neuronal growth (BDTF)
• Propagate calcium signals involved with memory
What is Microglia?
Are the smallest and least abundant glial cell, Engulf invading microorganisms and dead neurons, Derive from blood cells, Migrate to CNS during embryonic and fetal periods
What are. monocytes?
blood cells
What are phagocytes?
the macrophages of the CNS
What are Ependymal cells?
Line the central cavity of the spinal cord and brain, Ciliated—help circulate the cerebrospinal fluid
What are some examples of nueroglia in the CNS?
astrocytes, microglia, Ependymal cells,Oligodendrocytes
What is Oligodendrocytes?
have few branches, Wrap their cell processes around axons in CNS to form myelin sheaths
What is Satellite cells?
surround neuron cell bodies within ganglia
What is Schwann cells (neurolemmocytes)?
surround axons in the PNS
What are the neruoglia in the PNS?
Satellite cells and Schwann cells
What are thw two organizations of the brain?
Centrally located gray matter (unmyelinated) and Externally located white matter (myelinated)
Are internuerons mylinated or unmyelinated?
unmyelinated
What are the four regions of the brain?
Brain stem, cerebellum, Diencephalon, Cerebral hemispheres (also known as cerebrum
What consists of the brain stem?
Midbrain, pons, and medulla
What are the general function of the brain stem?
Passageway for all fiber tracts running between the cerebrum and spinal cord, Heavily involved with the innervation of the face and head, Produces automatic behaviors necessary for survival, Integrates auditory and visual reflexes
How many crainal nerves originate from the brain stem?
10 out of the 12
WHat are the crainal nerves htat are attached to the medulla?
VIII— vestibulocochlear nerve
• IX— glossopharyngeal nerve
• X— vagus nerve
• XII— hypoglossal nerve
What is the main nerve that regulates parsymethatic?
vagus nerve
What is the Decussation of the pyramids?
Crossing over of motor tracts
What is the most caudal part of the brain?
Medulla Oblongata
What is the reticular formation of the medulla?
Network of nerve pathways that influence autonomic functions
What does visceral centers in the medulla include?
Cardiac center
• Vasomotor center
• Respiratory center
• Centers for hiccupping, sneezing, swallowing,
and coughing
What is the pons?
A “bridge” between the midbrain and medulla oblongata
What central nerves are found in the pons?
V—trigeminal nerve
• VI—abducens nerve
• VII—facial nerve
What does the pons include other than the central nerves?
Motor tracts coming from the cerebral cortex