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Anatomy studies…
The structure of body parts and their relation to one another
What does the microscopic study of anatomy include?
Cytology (study of cells) and histology (study of tissues)
Physiology is…
The function of body parts
What are the two topics of physiology?
Organ and systemic
Physiology includes the principle of…
Complementary structure and function (form (shape) follows function)
What are the eight characteristics of life?
Homeostasis, organization, metabolism, growth, adaptation, response to stimuli, reproduction, DNA/RNA
Homeostasis:
Maintaining a stable internal environment
Organization:
Living things are made up of units (cells)
What is the unit that living cells are made up of?
Cells
Metabolism:
The combination of chemical reactions in which an organism builds up or destroys materials
Anabolism:
When metabolic processes construct materials
Catabolism:
When metabolic processes breakdown materials (cats break things)
Growth and development:
Single-celled organisms: increase in size
Multicellular organisms: cells divide and develop into different kinds of cells
Adaptation:
Having the capacity to evolve (natural selection, adaptation, evolution)
Response to stimuli:
The ability to detect and react to external (temperature and light) and internal (blood sugar or thirst) stimuli
Reproduction:
Ability to reproduce either asexually (bianary fission) or sexually
Universal genetic code:
DNA is the same genetic code for every living thing on earth
What are the main four levels of organization in the human body?
1. Cells
2. Tissues
3. Organs
4. Systems
Hierarchical approach:
Organism→organ system→tissues→cellular→organelle→molecule→atoms
Tissues:
Groups of similar cells that share a common function
What are the four types of tissues in the human body?
1. Muscle tissue
2. Nervous tissue
3. Connective tissue
4. Epithelial tissue
What is the purpose of the four types of tissues in the human body?
1. Muscle tissue (movement)
2. Nervous tissue (signal)
3. Connective tissue (support)
4. Epithelial tissue (cover)
Two or more tissues working together form…
Organs
Organ systems:
Organs working in tandem to accomplish a common function
Integumentary system:
Skin, hair and nails protect underlying skin
Muscular system:
Skeletal muscle move your bones
Skeletal system:
Bones provide a framework for support and protection
Cardiovascular system:
Heart pumps blood through vessels
Respiratory system:
Lungs absorb oxygen and release carbon dioxide
Urinary system:
Removes wastes from the blood and regulates bodily fluids
Reproductive system (male):
Produces and delivers sperm
Reproductive system (female):
Produces eggs and nourishes and shelters unborn baby
Nervous system:
Receives and sends electrical messages throughout body
Lymphatic system:
Returns leaked fluids to blood vessels and helps get rid of germs
Digestive system:
Breaks down food into nutrients to be absorbed
Endocrine system:
Glands that regulate body function by sending out chemical messengers
Internal environment is determined by physiological variables such as…
Temperature, pH, blood glucose, osmotic balance, blood O2/CO2, calcuim
A feedback system consists of…
A sensor, control center and effector
A sensor in a feedback loop does what?
Detects changes and sends signal to control center
A control center in a feedback loop does what?
Receives information from sensor and sends signals to effectors
An effector in a feedback loop does what?
Responds to signals from control center to effect change in a variable
Homeostatic imbalances:
Disturbances in homeostasis that can lead to disease or death
To prevent homeostatic imbalances, most variables are _________; maintained within a ________ range, close to a _____________
Controlled; narrow; normal value
Negative feedback loop:
Returns regulated variables to within “normal” range of values (pull) →:←
Positive feedback loops:
Increase/reinforce initial stimulus on regulated variable (positive, push, pregnancy)
How are structure and function related?
Complementary; form of structure is always such that best suits its function
___________ drive many physiological processes
Gradients (high→low)
What is required to coordinate body functions?
Cell communication
Endocrine cell signaling:
Act on distant target cells via blood vessels
Paracrine cell signaling:
Local cell-to-cell communication
Autocrine cell signaling:
Self; binds to cell-surface receptors on the same cell that produced it
Juxtracrine cell signaling:
Touch; contact of surface molecules in adjacent cells
Electron charge, location and mass:
-1, orbitals, 0
Proton charge, location and mass:
+1, nucleus, 1
Neutron charge, location and mass:
None, nucleus, 1
Atomic number:
Proton number
Atomic mass:
N(protons) + n(neutrons)
What’s the difference between atomic number and mass number?
Atomic number is the number of protons, while mass is equal to protons+neutrons
Atoms usually consist of…
Protons, neutrons and electrons
Electron shells:
Regions surrounding atomic nucleus where electrons exist
How many electrons can the first, second and third electron shells hold?
Two, eight, eight (satisfied with the octet rule)
Element:
Any substance made up of only one kind of atom
What are the four major elements found in the body?
Hydrogen, carbon, nitrogen, oxygen
Isotopes:
Atoms that differ only in the number of neutrons (and therefore mass)
Atomic weight:
Weighted average mass over all known isotopes of an element
How do isotopes chemically behave?
The same way
Radioisotope:
Physically unstable isotopes that decay over time
Why are radioisotopes unstable?
Contain high levels of nuclear energy and emit this energy as nuclear radiation
Do stable isotopes undergo radioactive decay?
No; they can exist in nature as stable compounds
What are some common uses of radioisotopes?
Cancer radiation therapy
Radiotracers
Treatment of thyroid disorders (iodine-131 treats overactive thyroid tissue)
What is the radioisotope gallium-67 used for?
Medical diagnoses
What is the radioisotope iodine-123 used for?
Diagnose thyroid disorders
What is the radioisotope iodine-125 used for?
Diagnose thyroid disorders and biomedical research
What are the two ways to combine matter?
Mixtures and chemical bonds
Mixture definition and examples:
Different atoms combined retain their chemical properties and can be separated; suspensions, colloids and solutions
Chemical bond definition and examples:
Different atoms combined have new chemical properties and the resulting molecules can only be separated chemically; ionic, covalent and hydrogen bonds
Solutions:
Completely mixed; small, evenly distributed particles will not settle out
Solutions contain a __________ (substance dissolved) and a _________ (substance that dissolves)
Solute; solvent
The solute is ________ if dissolved
Soluble
Suspension:
Mixture containing large, unevenly distributed particles that will settle out when undisturbed (think lava lamp)
Colloids:
Mixture containing small, evenly distributed particles that will not settle out
Why are some atoms chemically reactive and others are not?
Valence shells and the octet rule
Chemical bonds are an ____________ between atoms
Energy relationship
Molecule:
Formed by chemical bonding between two or more atoms of the same element
Compound:
Formed when two or more atoms from different elements combine by chemical bonding
Chemical bonds are formed when valence electrosn of atoms ________
Interact
Octet rule:
Atom is most stable when eight electrons in valance shell
Duet rule matters with atoms with…
Five or fewer electrons
Duet rule:
Atom is most stable when valence shell holds two electrons
Ions:
Charged particles
Ionization can cause…
Cations (+) and anions (-)
Electrolytes:
Substances that ionize in water
What can electrolytes conduct?
Electricity
Ionic bonds:
Transfer of electrons between atoms
Non-polar covalent bonds:
Equal sharing of electrons
Polar covalent bonds:
Unequal sharing of electrons
Hydrogen bonds:
Attractions between polar molecules; very weak
Van de Waal’s forces:
Weak attractions between nonpolar molecules
What is the strongest chemical bond?
Non-polar covalent bonds
What are the three basic types of energy?
Chemical
Electrical
Mechanical