DCA quiz 2

brand name of sumatriptan

imitrex

generic name of imitrex

sumatriptan

dosage forms of sumatriptan/imitrex

oral tablet, nasal solution, transdermal patch, injectable

therapeutic class of sumatriptan/imitrex

anti migraine serotonin receptor agonist

common indications for sumatriptan/imitrex

migraine, cluster headaches

EMP of sumatriptan/imitrex

resolution of clinical signs of migraine headache

MOA of sumatriptan/imitrex

binds with high affinity to serotonin (5-HT) receptors. serotonin receptor agonists are believed to be effective in migraine either through vasoconstriction or through activation of 5-HT receptors on sensory nerve endings in the trigeminal system resulting in the inhibition of inflammation

patient consultation for sumatriptan/imitrex

avoid activities requiring mental alertness or coordination until drug effects are realized, as this drug may cause dizziness or somnolence

brand name of rizatriptan

maxalt

generic name of maxalt

rizatriptan

therapeutic class of rizatriptan/maxalt

anti migraine serotonin receptor agonist

dosage forms of rizatriptan/maxalt

tablet, disintegrating tablet

common indications for rizatriptan/maxalt

migraine

EMP of rizatriptan/maxalt

resolution of clinical signs of migraine headache

MOA of rizatriptan/maxalt

binds with high affinity to serotonin (5-HT) receptors. serotonin receptor agonists are believed to be effective in migraine either through vasoconstriction or through activation of 5-HT receptors on sensory nerve endings in the trigeminal system resulting in the inhibition of inflammation

patient consultation for rizatriptan/maxalt

allow disintegrating tablet to dissolve on tongue and then swallow, do not chew, caution with driving and other tasks requiring alertness, avoid alcohol and other CNS depressants

brand name of codeine

tylenol with codeine, tylenol

therapeutic class of codeine/tylenol

opioid analgesic

controlled substance schedule for codeine/tylenol

C-II, C-III, or C-V depending on amount (C-IV in SD)

dosage forms of codeine/tylenol

oral tablet (codeine alone), oral tablet (with acetaminophen), oral elixir/solution (with acetaminophen)

common indications for codeine/tylenol

acute pain, cough

EMP of codeine/tylenol

decreased pain

MOA of codeine/tylenol

an opioid with very low affinity for opioid receptors. its analgesic activity appears to result from conversion to morphine

patient consultation for codeine/tylenol

use a laxative for preventing constipation, may cause drowsiness, avoid driving or other tasks requiring motor coordination, avoid alcohol and other CNS depressants

brand name of fentanyl (transdermal)

duragesic

generic name for duragesic

fentanyl (transdermal)

therapeutic class of fentanyl (transdermal)/duragesic

opioid analgesic

dosage forms of fentanyl (transdermal)/duragesic

transdermal patch

controlled substance schedule for fentanyl (transdermal)/duragesic

C-II

common indications for fentanyl (transdermal)/duragesic

pain, chronic (moderate to severe)

EMP for fentanyl (transdermal)/duragesic

decreased pain

MOA of fentanyl (transdermal)/duragesic

an opioid agonist with predominant effects on the mu opioid receptor and is about 50-100 times more potent as an analgesic than morphine

patient consultation for fentanyl (transdermal)/duragesic

use a laxative for preventing constipation, may cause drowsiness, avoid driving or other tasks requiring motor coordination, avoid alcohol and other CNS depressants, apply to clean dry skin, skin breaks may increase absorption, remove old patch before applying new patch to skin, febrile patients may have increased absorption

brand name of hydrocodone with acetaminophen (rare-hydrocodone alone/ with ibuprofen)

ricodin, norco, lortab, lorcet (combo products with acetaminophen)

generic name of ricodin, norco, lortab, lorcet

hydrocodone with acetaminophen

therapeutic class of hydrocodone with acetaminophen/ricodin/norco/lortab/lorcet

opioid analgesic

controlled substance schedule of hydrocodone with acetaminophen/ricodin/norco/lortab/lorcet

C-II

dosage forms of hydrocodone with acetaminophen/ricodin/norco/lortab/lorcet

oral tablet, oral elixir/solution, oral tablet (ER 24 hr abuse deterrent), oral capsule (ER 12 hr abuse deterrent)

common indications for hydrocodone with acetaminophen/ricodin/norco/lortab/lorcet

pain, severe

EMP for hydrocodone with acetaminophen/ricodin/norco/lortab/lorcet

decreased pain

MOA of hydrocodone with acetaminophen/ricodin/norco/lortab/lorcet

an opioid analgesic and antitussive with unknown MOA but it is thought to be related to the presence of opiate receptors in the CNS

patient consultation for hydrocodone with acetaminophen/ricodin/norco/lortab/lorcet

use a laxative for preventing constipation, may cause drowsiness, avoid driving or other tasks requiring motor coordination, avoid alcohol and other CNS depressants

brand name of morphine sulfate (extended release)

MS contin, kadian

generic name of MS contin, kadian

morphine sulfate (ER)

therapeutic class of morphine sulfate (ER)/MS contin, kadian

opioid analgesic

controlled substance schedule of morphine sulfate (ER)/MS contin, kadian

C-II

dosage forms of morphine sulfate (ER)/MS contin, kadian

oral tablet, oral tablet (ER), oral tablet (ER, abuse deterrent), oral capsule (ER, 24 hr), oral solution, rectal suppository, injectable

common indications for morphine sulfate (ER)/MS contin, kadian

chronic pain (moderate to severe), acute pain

EMP for morphine sulfate (ER)/MS contin, kadian

decreased pain

MOA of morphine sulfate (ER)/MS contin, kadian

morphine is a pure mu opioid agonist. mu receptors are responsible for analgesia, respiratory depression, miosis, decreased GI motility and euphoria

patient consultation for morphine sulfate (ER)/MS contin, kadian

use laxative for preventing constipation, may cause drowsiness, avoid driving or other tasks requiring motor coordination, avoid alcohol and other CNS depressants, ER products must not be crushed or chewed, this will release the total dose of morphine all at once and increase risk of respiratory depression, ER capsule can be opened and sprinkled on soft food but must be swallowed whole and not chewed

brand name of oxycodone/oxycodone with acetaminophen

oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

generic name of oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

oxycodone, oxycodone with acetaminophen

therapeutic class of oxycodone, oxycodone with acetaminophen/oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

opioid analgesic

controlled substance schedule of oxycodone, oxycodone with acetaminophen/oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

C-II

dosage forms of oxycodone, oxycodone with acetaminophen/oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

oral capsule, oral tablet, oral tablet (ER 12 hr abuse deterrent), oral capsule (12 hr abuse deterrent), oral solution/concentrate

common indications for oxycodone, oxycodone with acetaminophen/oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

chronic pain (moderate to severe)

EMP of oxycodone, oxycodone with acetaminophen/oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

decreased pain

MOA of oxycodone, oxycodone with acetaminophen/oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

a pure mu agonist. mu receptors are responsible for analgesia, respiratory depression, miosis, decreased GI motility, and euphoria

patient consultation for oxycodone, oxycodone with acetaminophen/oxycontin, roxicodone, with acetaminophen= percocet, roxicet, endocet

use laxative for preventing constipation, may cause drowsiness, avoid driving or other tasks requiring motor coordination, avoid alcohol and other CNS depressants

brand name of tramadol

ultram

generic name of ultram

tramadol

therapeutic class of tramadol/ultram

opioid analgesic

controlled substance schedule of tramadol/ultram

C-IV

dosage forms of tramadol/ultram

oral tablet, oral tablet (ER), oral capsule (ER 24 hr), oral solution

common indications of tramadol/ultram

chronic pain (moderate to moderately severe)

EMP of tramadol/ultram

decreased pain

MOA of tramadol/ultram

a mu agonist and a weak inhibitor of serotonin and norepinephrine reuptake. mu receptors are responsible for analgesia, respiratory depression, miosis, decreased GI motility, and euphoria

patient consultation for tramadol/ultram

use laxative for preventing constipation, may cause drowsiness, avoid driving or other tasks requiring motor coordination, avoid alcohol and other CNS depressants, ER products must not be crushed or chewed but may be taken with or without food, and always the same way to avoid variability in absorption

brand name of buprenorphine with naloxone

suboxone

generic name of suboxone

buprenorphine with naloxone

therapeutic class of buprenorphine with naloxone/suboxone

opioid partial agonist and antagonist combination

controlled substance schedule of buprenorphine with naloxone/suboxone

C-III

dosage forms of buprenorphine with naloxone/suboxone

sublingual film, sublingual tablet, buccal film

common indications for buprenorphine with naloxone/suboxone

opioid use disorder

EMP of buprenorphine with naloxone/suboxone

using urine drug screening tests that are negative for illicit drugs. relief of signs and symptoms associated with narcotic addiction

MOA of buprenorphine with naloxone/suboxone

an opioid receptor partial agonist that causes opioid withdrawal when injected parenterally and is included in the formulation to reduce the risk of abuse

patient consultation for buprenorphine with naloxone/suboxone

use laxative for preventing constipation, may cause drowsiness, avoid driving and other tasks requiring motor coordination, avoid alcohol and other CNS depressants, do not crush or swallow the SL tablet, place the tablet/film under the tongue until it is dissolved, do not chew or swallow, if using the buccal film, press and hold film to moistened cheek for 5 seconds with finger, if you need an additional film, place on inside of the other cheek, do not use more than 2 buccal films simultaneously