Immune Organs

week 1

The primary lymphoid organs include the_____ ____ and then _____

bone marrow thymus

Where does Tcells originate from and where does it go to mature

originates from bone marrow and matures in the thymus.

The secondary lymphoid organs include the____and _____ ______

Lymph nodes, spleen, MALT

The thymus is located just above the___ and below the ____

heart, sternum

1. Which of the following is NOT considered a classical immune organ?

• A) Bone marrow

• B) Thymus

• C) Skin

• D) Spleen

Skin

1. What is the primary function of the spleen in the immune system?

• A) To produce red blood cells

• B) To filter blood and trap pathogens

• C) To produce antibodies

• D) To store iron

To filter blood and trap pathogens

1. What happens to T cells in the thymus during negative selection?

• A) They are programmed to recognize pathogens

• B) They are deleted if they bind too strongly to self-MHC

• C) They become double positive

• D) They leave the thymus and enter the bloodstream

They are deleted if they bind too strongly to self-MHC

1. Which of the following is a secondary lymphoid organ?

• A) Bone marrow

• B) Thymus

• C) Spleen

• D) Skin

Spleen

1. What is the role of dendritic cells in the immune system?

• A) To produce antibodies

• B) To present antigens to T cells

• C) To destroy old blood cells

• D) To circulate in the bloodstream

To present antigens to T cells

Where does hematopoiesis primarily occur in adults?

A. Thymus

B. Spleen

C. Bone marrow

D. Lymph nodes

Bone marrow

Which process eliminates T cells that strongly bind self-antigens?

A. Positive selection
B. Clonal expansion
C. Negative selection
D. Isotype switching

Negative selection

What is the function of white pulp in the spleen?

A. Phagocytosis of old red blood cells
B. Hematopoiesis
C. Site for lymphocyte activation and immune response.
D. Production of platelets

Site for lymphocyte activation and immune response.

What type of T cells emerge from thymic maturation?

A. CD19+ B cells
B. CD4+ and CD8+ T cells
C. Natural killer cells
D. Plasma cells

CD4+ and CD8+ T cells

What happens to the thymus as a person ages?

A. It enlarges
B. It remains the same size
C. It involutes
D. It converts to lymph nodes

It involutes