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Screening test (antepartal)
Identifies at-risk pregnancies, not diagnostic. Examples: NST, BPP, CST, multiple marker screening, AFI, Doppler flow. Abnormal results → follow-up with diagnostic tests.
Diagnostic test (antepartal)
Confirms or rules out disease. Examples: Amniocentesis, CVS, PUBS, MRI, specialized ultrasound. Reserved for high-risk pregnancies.
Fetal movement (kick counts)
Begin at 28 weeks. Normal = ≥10 movements in 2 hrs OR ≥4 movements in 1 hr. Decreased movement = report → further testing (NST/BPP). Affected by fetal sleep, maternal meds, smoking.
Ultrasound in pregnancy
Transabdominal/transvaginal. Uses: gestational dating, anatomy, growth, HR, breathing. Advantages: safe, noninvasive. NTK: first-line for anomalies, IUGR, and previa diagnosis.
Amniotic Fluid Index (AFI)
Normal 5-25 cm. <5 = oligohydramnios → IUGR, distress. >25 = polyhydramnios → risk of cord prolapse, malpresentation.
Biophysical Profile (BPP)
5 variables: NST, breathing, movements, tone, AFI. Score 8-10 = normal; 6 = equivocal; ≤4 = abnormal → delivery. Modified BPP = NST + AFI only.
Nonstress Test (NST)
Reactive = ≥2 accelerations (≥15 bpm x 15 sec in 20 min; if <32 wks, ≥10x10). Nonreactive = insufficient accelerations in 40 min → further testing.
Contraction Stress Test (CST)
3 contractions/10 min required.
Negative (normal) = no late decels.
Positive = late decels with ≥50% contractions → uteroplacental insufficiency.
Contraindications: previa, abruption, preterm labor.
Multiple marker screening (AFP, triple, quad)
↑ AFP = neural tube/abdominal wall defects.
↓ AFP = Trisomy 21.
Used as screening only, follow up with diagnostic testing.
Amniocentesis
Done 15-20 wks (genetics) or later (lung maturity; L/S ratio ≥2:1). Risks: miscarriage, infection, bleeding. Nursing: light activity 24h, ↑ fluids, report bleeding/fluid leakage, Rhogam if Rh-. Accuracy ~99%.
Chorionic Villus Sampling (CVS)
10-13 wks; early genetic diagnosis. Risks: SAB, bleeding, infection. Nursing: monitor FHR, post-procedure Rhogam for Rh-, teach to report pain, bleeding, fever.
PUBS (Percutaneous Umbilical Blood Sampling)
Direct fetal blood sampling via umbilical vein. Used for anemia, genetic studies, infections. High risk → only in specialized centers.
Hyperemesis gravidarum
Severe vomiting → >5% weight loss, dehydration, ketonuria. Risks: multiples, migraines, family hx. Tx: IV fluids, antiemetics, TPN last resort. Nursing: I&O, weight, labs, psychosocial support.
Multiple gestation risks
Maternal: preE, GDM, previa, abruption, anemia, hemorrhage, C/S. Fetal: prematurity, growth restriction, malformations. Highest risk = mono-mono twins.
Gestational diabetes (GDM) screening
24-28 wks, 50g GTT → if abnormal, 3-hr OGTT. GDM A1 = diet controlled; GDM A2 = insulin controlled. Risks: macrosomia, hypoglycemia, RDS, stillbirth.
Diabetes in pregnancy nursing care
Teach glucose monitoring, diet/exercise, kick counts, S/S hypo/hyperglycemia. Monitor for polyhydramnios, macrosomia. Delivery planning individualized.
Spontaneous abortion (SAB)
<20 wks. S/S: bleeding, cramping, partial/complete expulsion.
Tx: expectant, misoprostol, D&C.
Nursing: bleeding precautions, Rhogam if indicated, emotional support.
Ectopic pregnancy
Implantation outside uterus (95% fallopian tube).
S/S: unilateral pain, bleeding, shoulder pain, syncope.
Dx: hCG + transvaginal US.
Tx: methotrexate (stable), surgery (rupture).
Placenta previa
Placenta over cervix. Painless 3rd-trimester bleeding. Soft, nontender uterus. Risks: previa hx, scarring, multiples. Tx: pelvic rest, C/S delivery, avoid vaginal exams.
Placental abruption
Premature separation of placenta. Painful bleeding, rigid uterus, abnormal FHR. Risks: HTN, trauma, cocaine. Complications: hemorrhage, DIC, fetal demise. Tx: stabilize, emergent delivery.
Gestational hypertension
HTN after 20 wks without proteinuria. Can progress to preeclampsia in 25%.
Preeclampsia
HTN + proteinuria OR end-organ dysfunction (low platelets, ↑ LFTs, renal dysfunction, neuro changes, epigastric pain). Risks: nulliparity, age >35, obesity, DM, multiples.
Eclampsia
Seizures in preeclampsia. Emergency.
Risks: stroke, cerebral edema, abruption.
Nursing: seizure precautions, Mg sulfate, airway support.
HELLP syndrome
Hemolysis, Elevated Liver enzymes, Low Platelets. Severe preE complication. Risks: abruption, DIC, maternal death. Tx: delivery.
Magnesium sulfate in pregnancy
Uses: seizure prophylaxis, fetal neuroprotection, tocolytic. Dose: 4-6g load, then 1-2g/hr. Therapeutic 4-8 mEq/L. Toxicity: ↓ DTRs, RR<12, UO<30mL/hr, SOB. Antidote: Calcium gluconate 1g IV.
Antihypertensives in pregnancy
Severe HTN → Labetalol IV, Hydralazine IV, Nifedipine PO. Goal = prevent stroke/maternal complications.
Antenatal steroids
Betamethasone (12mg IM x2) or Dexamethasone (6mg IM x4). Given 24-34 wks if preterm birth expected. Benefits: ↓ RDS, IVH, NEC, neonatal death. Optimal window = 2-7 days before delivery.
PPROM (preterm premature rupture of membranes)
ROM before 37 wks. Risks: infection, abruption, prematurity. Dx: sterile speculum, ROM+ tests, US. Tx: depends on GA; steroids, abx, Mg sulfate. Teach to monitor temp, fetal movement.
Group B Strep (GBS)
Screen 36-37 wks. Causes neonatal pneumonia, sepsis, meningitis. Tx: IV penicillin during labor (cefazolin/clindamycin if allergic).
Placenta accreta spectrum
Placenta abnormally invades uterus. Accreta = superficial, increta = myometrium, percreta = into organs. Risk: prior C/S. Tx: planned C/S hysterectomy.
Trauma in pregnancy
Leading cause of maternal death in pregnancy (MVA, IPV). Complications: abruption, hemorrhage, uterine rupture, fetal demise. Maternal stabilization takes priority.
HIV in pregnancy
Transmission in utero, delivery, breastfeeding. Tx: antiretrovirals, IV meds in labor, avoid instruments, no breastfeeding. Risks: IUGR, PTL, PPROM, neonatal infection.