Monoclonal Antibodies and Their Mechanisms of Action

A collection of flashcards detailing different monoclonal antibodies and their mechanisms of action in medical treatments.

Monoclonal Antibodies (MAB)

Laboratory-made molecules that can mimic the immune system's ability to fight off harmful pathogens.

Adalimumab

A monoclonal antibody that inhibits TNF (Tumor Necrosis Factor), used to treat autoimmune conditions.

Infliximab

A monoclonal antibody that targets TNF, primarily used for autoimmune diseases.

Tocilizumab

An anti-IL-6 monoclonal antibody used in the treatment of rheumatoid arthritis and other inflammatory conditions.

Bevacizumab

A monoclonal antibody that inhibits Vascular Endothelial Growth Factor (VEGF) to prevent tumor growth.

Anakinra

An IL-1 receptor antagonist used to reduce inflammation in various autoimmune diseases.

Omalizumab

An anti-IgE antibody that is used to treat allergic asthma and chronic idiopathic urticaria.

Natalizumab

A monoclonal antibody that blocks alpha-4 integrin, used to treat multiple sclerosis and Crohn's disease.

Abatacept

A CTLA4 agonist that modulates the immune system, primarily used in rheumatoid arthritis.

Ipilimumab

A CTLA4 antagonist that enhances immune response against cancer cells.

Aldesleukin

An IL-2 analog that promotes the growth of T cells and is used in certain cancer treatments.

Etanercept

A decoy receptor for TNF that is used as an anti-inflammatory treatment in autoimmune diseases.