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primary goal of all energy systems
to make ATP, which fuels cellular energy production
metabolic balance
balance between anabolism (building molecules, energy storage) and catabolism (breaking molecules, energy release)
when does energy breakdown dominate
during exercise (more catabolism than anabolism)
when does energy building dominate
during recovery/eating (more anabolism than catabolism)
why is ATP so important
ATP powers both anabolic (building) and catabolic (breaking down) reactions in the body
how much ATP do we store in the body at once
only about 100g
how fast can we burn ATP at the start of strenuous exercise
about 450g per minute
how much ATP do we break down in a whole day
around 45 kg
what is the fastest energy system
phosphagen (PCr) system
how does phosphocreatine make ATP
PCr + creatine kinase -> splits into creatine + inorganic phosphate -> energy released to make ATP
does the phosphagen system use carbs, fats, or protein
no, it doesn't use macronutrients
when is the phosphagen system used
short, powerful bursts (ex: sprints, heavy lifting, jumps))
what happens during anaerobic glycolysis
glucose is broken down quickly -> produces 2-3 ATP, 2 pyruvate, 2 NADH
which enzyme controls glycolysis
phosphofructokinase (PFK) responds to ATP:ATP ratios
what happens to pyruvate in anaerobic glycolysis
if mitochondria can handle it, it goes to Krebs cycle (if not its converted into lactate)
what actually causes the burn in muscles during exercise
hydrogen ions (H+), not lactate (lactate actually buffers hydrogen and helps delay fatigue
what is aerobic metabolism
energy production using oxygen (produces the most ATP and keeps the body functioning normally)
where does aerobic metabolism occur
in the mitochondria
what is the meeting point of all macronutrients
Acetyl-CoA, which enters the Krebs cycle
what does oxaloacetate do in the Krebs cycle
combines with Acetyl-CoA to form citrate (starting the cycle)
how much ATP is produced from one glucose molecule aerobically
around 30-32 ATP
what drives ATP synthase in the electron transport chain
a hydrogen gradient created by electron transport (chemiosmotic coupling)
how are carbs used for energy
glycolysis -> Krebs cycle -> ETC
why are carbs important for fat metabolism
carbs provide oxaloacetate, which is needed to keep the Krebs cycle running
what happens if glucose is too low
oxaloacetate is used for gluconeogenesis -> Krebs slows -> Acetyl-CoA becomes ketones
why are fats considered the highest energy molecule
they yield the most ATP when broken down
what is the process of fat breakdown called
beta-oxidation
what are the products of each beta-oxidation cycle
1 Acetyl-CoA, 1 NADH, 1 FADH2
when is fat breakdown limited
starvation or very low carbs (not enough oxaloacetate)
low-carb diets (harder to burn fat efficiently)
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