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cell cycle
a continuous sequence of cell growth and division; the life cycle of a cell
somatic cell
any of the cells of a multicellular organism except those that form gametes
parent cell
original cell that divides to produce two new daughter cells during cell division
daughter cell
any one of two cells produced from the division of a parent cell
DNA
a double-stranded nucleic acid molecule that governs the processes of heredity in the cells of organisms; composed of nucleotides containing a phosphate group, a nitrogenous base (adenine, guanine, cytosine, or thymine), and deoxyribose
Chromosome
a length of DNA and its associated proteins
Histones
protein found in chromosomes; acts as scaffold around which DNA winds, enabling it to fit within the small space of the nucleus
Chromatin
long fibres that form chromosomes and contain DNA, a small amount of RNA, and various proteins; non-condensed form of genetic material that predominates for most of the cell cycle
Centromere
the point at which two sister chromatids of a chromosome are joined and to which the spindle fibres are attached during mitosis
homologous chromosomes
chromosome that contains the same gene sequence as another, but that may not be made up of the same alleles; human somatic cells have 22 pairs of these, known as autosomes, and females also have a homologous pair of X sex chromosomes; males have an X and a Y sex chromosome which are not homologous
Autosomes
chromosome other than a sex chromosome; human somatic cells have 22 pairs of these
sex chromosomes
X or Y chromosome that carries the genes involved in determining the genetic sex of an individual
Genes
the basic unit of heredity; a specific sequence of DNA that encodes a protein, tRNA, rRNA molecule, or regulates the transcription of such a sequence; governs the expression of a particular trait and can be passed to an offspring
Locus
specific location on a chromosome
Allele
different form of the same gene occurring on homologous chromosomes
Diploid
describing a cell that contains two pairs of every chromosome, designated as 2n; e.g., somatic cells
Haploid
describing a cell containing half the number of chromosomes (n) that the diploid (2n) parent cell contains; condition occurring in gametes, either egg (ovum) or sperm
Gamete
male or female haploid reproductive cell; e.g., egg (ovum) and sperm
Polyploid
describing a cell which contains sets of more than two homologous chromosome
Karyotype
the particular set of chromosomes that an individual possesses
Interphase
growth stage of a somatic cell; there are 3 phases
G1 phase
the first part of interphase, a somatic cell’s growth stage, during which cells carry out rapid growth and metabolic activity; also known as Growth 1 or Gap 1
S phase
the middle part of interphase, a somatic cell’s growth stage, during which the cell’s DNA is replicated
sister chromatids
two chromatids in a chromosome that are genetically identical and are held together by a centromere
G2 phase
the last part of interphase, a somatic cell’s growth stage, during which the cell rebuilds its reserves of energy and manufactures proteins and other molecules to prepare for division; also known as Growth 2 or Gap 2
Mitosis
one of the two main processes in cell division
Cytokinesis
one of the two main processes in cell division; consists of separation of cytoplasm and organelles and the formation of two daughter cells
Prophase
the first of the four phases in cell division (mitosis), when chromatin condenses and can be seen as tightly packed chromosomes; the nuclear membrane breaks down, centrioles move to opposite poles of the cell, and the spindle apparatus forms
Centriole
one of a pair of cylindrical organelles that moves to opposite poles of the cell during prophase of mitosis; provides an attachment for the spindle apparatus
spindle apparatus
assembly that carries out the separation of chromosomes during cell division (mitosis); composed of spindle fibres and assembled during prophase
Metaphase
the second stage of cell division (mitosis) during which chromosomes line up at the cell’s equator in preparation for separation
Anaphase
a late stage of cell division (mitosis) during which the centromere splits apart and chromosomes move to opposite poles of the cell; by the end of the phase, one complete diploid set of chromosomes has been gathered at each pole
Telophase
the final stage of cell division (mitosis) in which a nucleolus forms around chromosomes at opposite ends of the dividing parent cell; this stage is followed by cytokinesis to form two daughter cells
cell plate
structure across a dividing plant cell that signals the location of new plasma membranes and cell walls
Cancer
group of diseases associated with uncontrolled, rapid cell division
Meiosis
the cellular process that produces haploid gametes from diploid cells in the ovaries and testes
reduction division
one of the outcomes of meiosis
Recombination
one of the outcomes of meiosis which is cell division that produces daughter cells with different combinations of genes than the parent cells; gives rise to offspring that are genetically distinct from one another and from their parents
meiosis I
the first of two sequences in meiotic cell division in which the chromosomes are reduced from diploid to haploid (2n to n)
meiosis II
the second of two sequences in meiotic cell division in which each of the haploid cells created during meiosis I undergoes mitosis (without an interphase)
germ cells
gamete-producing cell in the male and female gonads
Synapsis
aligning of homologous chromosomes side-by-side during prophase I in meiosis
Tetrad
a homologous pair formed during prophase I of meiosis, so named because it contains four chromatids
non-sister chromatids
in a tetrad, those chromatids that do not belong to the same chromosome; undergo crossing over during prophase I of meiosis
crossing over
the process by which non-sister chromatids exchange genes during prophase I of meiosis, allowing for the recombination of genes
Nondisjunction
failure of homologous chromosomes pairs or sister chromatids to separate during meiosis I and meiosis II, respectively
Spermatogenesis
the process of male gamete (sperm) production in animals
Oogenesis
the process of female gamete (ova or egg) production in animals
Spermatogonium
the diploid germ cell from which sperm are produced in the testes
primary spermatocyte
one of two daughter cells formed by division of the spermatogonia; the other daughter cell replenishes the spermatogonia population
secondary spermatocyte
each of two cells produced as a result of a primary spermatocyte undergoing meiosis I
Spermatids
each of four haploid cells that result when a secondary spermatocyte undergoes meiosis II; each spermatid differentiates into a sperm cell
Oogonium
the diploid germ cell from which eggs are produced in the ovaries
primary oocyte
each of two cells formed when an oogonium undergoes mitosis
secondary oocyte
cell that receives the larger portion of cytoplasm when a primary oocyte undergoes asymmetrical cytokinesis during meiosis I; becomes the egg
first polar body
cell that receives the smaller portion of cytoplasm when a primary oocyte undergoes asymmetrical cytokinesis during meiosis I; is not functional and soon degenerates; compare secondary oocyte
second polar body
one of a pair of cells that results when when a secondary oocyte undergoes asymmetrical cytokinesis during meiosis II; is not a viable gamete; also used to refer to the products of a second division that may occur in the first polar body
asexual reproduction
reproduction that requires only one parent and does not involve gametes; produces genetically identical offspring
sexual reproduction
reproduction involving meiosis, gamete formation, and fertilization; produces genetically distinct offspring
binary fission
asexual reproductive process of cell division in bacteria; produces genetically identical populations
Conjugation
in micro-organisms, a process of reproduction that involves the transfer of genetic material from one cell to another by cell-to-cell contact through a bridging structure; creates cells with new genetic combinations
Pilus
extensions of a bacterial cell enabling it to transfer genetic materials from one individual to another through the process of conjugation
Budding
asexual form of reproduction whereby a new organism develops as an outgrowth of the body of the parent
vegetative reproduction
a form of asexual reproduction in which a new plant grows from a modified stem
Fragmentation
form of asexual reproduction in which a new organism is created from a fragment (portion) of a parent organism
Parthenogenesis
form of asexual reproduction in which an unfertilized egg develops into an adult
Spore
reproductive cell capable of developing into a new organism without fusion with another cell, in contrast to a gamete; contains genetic material and cytoplasm surrounded by a protective sheath or wall
alternation of generations
term describing the life cycle of a plant that alternates between a diploid sporophyte generation and a haploid gametophyte generation
Sporophyte
diploid generation of a plant that produces haploid spores (through the process of meiosis) that develop without fertilization into a gametophyte; also see alternation of generations
Gametophyte
haploid generation of a plant; produces male and female gametes that fuse at fertilization to form a diploid sporophyte; also see alternation of generations