MYCOBACTERIUM MOCK QUIZ

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GRAM POSITIVE OR GRAM NEGATIVE. MYCOBACTERIA SPECIES

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1

GRAM POSITIVE OR GRAM NEGATIVE. MYCOBACTERIA SPECIES

GRAM POSITIVE

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2

TRUE OR FALSE. MYCOBACTERIA SPECIES ARE GRAM (+), ACID-FAST, SLENDER, THIN COCCI

FALSE

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3

FOR PATHOGENIC MYCOBACTERIA SPECIES, THEY REQUIRE HOW MANY DAYS FOR IT TO SHOW EVIDENT GROWTH IN A CULTURE MEDIA?

MORE THAN 5 DAYS

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4

SINCE MYCOBACTERIA SPECIES REQUIRE HIGH PROTEIN CONTENT, WHAT DO THEY NEED FOR GROWTH?

WHOLE EGG

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5

NON PATHOGENIC MYCOBACTERIUM SPECIES ARE WHAT KIND OF GROWERS?

RAPID GROWERS

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6

WHAT MYCOBACTERIA SPECIE IS A NON-CULTURABLE IN VITRO?

MYCOBACTERIUM LEPRAE

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7

WHAT IS USED TO CULTURE MYCOBACTERIUM LEPRAE?

FOOTPADS OF ARMADILLO OR FOOTPADS OF MOUSE

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8

SINCE MYCOBACTERIUM SPECIES HAVE A HIGH LIPID-CONTAINING CELL WALL, THEY ARE REGARDED AS?

ACID-FAST

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9

TRUE OR FALSE. WHEN MYCOBACTERIUM SPECIES ARE STAINED, THEY ARE MORE DIFFICULT TO DECOLORIZE ESPECIALLY WITH THE USE OF ACID ALCOHOL

TRUE

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10

MYCOBACTERIUM TUBERCULOSIS IS ALSO KNOWN AS?

KOCH’S BACILLUS OR TUBERCLE BACILLUS

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11

M. TUBERCULOSIS WAS FIRST DESCRIBED BY?

ROBERT KOCH (1882)

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12

WHAT IS THE INCLUSION BODY OF M. TUBERCULOSIS

MUCH GRANULES

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13

COLONY APPEARANCE OF MYCOBACTERIUM TUBERCULOSIS

CAULIFLOWER LIKE

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14

THE COLONY APPEARANCE OF M. TUBERCULOSIS IS EVIDENT WHEN INCUBATED AT WHAT TEMP?

35-37C

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15

ASIDE FROM M. TUBERCULOSIS BEING OBLIGATE AEROBE, THEY ALSO REQUIRE ______ FOR GROWTH

5-10% CARBON DIOXIDE

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16

THIS IS THE PRINCIPAL AGENT OF TUBERCULOSIS IN MAN

MYCOBACTERIUM TUBERCULOSIS

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17

MODE OF TRANSMISSION OF M. TUBERCULOSIS

INHALATION OF VIABLE BACILLI

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18

ONLY ____ OF INFECTED INDIVIDUAL DEVELOPS A DISEASE

15-20%

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19

WHAT DISEASE REMAINS AS ONE OF THE MOST LEADING CAUSE OF MORTALITY AND MORBIDITY WORLDWIDE

TUBERCULOSIS

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20

______ OF THE WORLD’S POPULATION IS INFECTED WITH M. TUBERCULOSIS

1/3

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21

WHAT IS THE VIRULENCE FACTOR OF M. TUBERCULOSIS

CORD FACTOR

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22

CORD FACTOR IS ALSO KNOWN AS?

SERPENTINE FACTOR

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23

THE VIRULENCE FACTOR OF M. TUBERCULOSIS IS MADE UP OF?

TREHALOSE DIMYCOLATE

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24

THIS VIRULENCE FACTOR INHIBITS LEUKOCYTE MIGRATION

CORD FACTOR

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25

WHAT DO YOU CALL WHEN A WBC MIGRATES TO THE SITE OF INFECTION

CHEMOTAXIS

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26

CORD FACTOR ACTIVATES ________ CREATING ________

MACROPHAGE; GRANULOMA FORMATION

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27

WHAT DO YOU CALL THE SCAR FORMATION CAUSED BY M. TUBERCULOSIS

GHON LESIONS

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28

CORD FACTORS INDUCES RELEASE?

TUMOR NECROSIS FACTOR ALPHA (TNF-ALPHA)

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29

CORD FACTOR CAUSES MYCOBACTERIUM TUBERCULOSIS TO HAVE ______ UNDER THE MICROSCOPE

PARALLEL ARRANGEMENT

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30

SULFATIDE INHIBITS WHAT?

PHAGOLYSOSOMAL FUSION

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31

THIS IS USUALLY SEEN IN CHILDREN AND PATIENTS WHO HAS INITIAL EXPOSURE

PRIMARY TUBERCULOSIS

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32

A PRIMARY TUBERCULOSIS THAT HAS NO APPARENT SIGNS AND SYMPTOMS, NOT INFECTIOUS

LATENT TUBERCULOSIS

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33

A PRIMARY TUBERCULOSIS THAT OCCURS WHEN IMMUNE SYSTEM IS SUPPRESSED

REACTIVATION TUBERCULOSIS

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34

THIS IS WHEN PATIENTS WHO ACQUIRED TUBERCULOSIS FROM ANOTHER INDIVIDUAL WITH TUBERCULOSIS

SECONDARY TUBERCULOSIS

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35

MILITARY TUBERCULOSIS IS ALSO KNOWN AS?

MENINGEAL TB, DISSEMINATED TB

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36

MILITARY TUBERCULOSIS IS A TYPE OF WHAT TB?

EXTRA PULMONARY TUBERCULOSIS

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37

TUBERCULOSIS OF THE SPINE

POTT’S DISEASE

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38

WHAT IS THE OTHER TERM FOR POTT’S DISEASE

TUBERCULAR SPONDYLITIS, SKELETAL TB

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39

PRIMARY ANTI-TB DRUGS

RIFAMPICIN, ISONIAZID, PYRAZINAMIDE, ETHAMBUTOL (STREPTOMYCIN)

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40

WHAT IS/ARE THE MOST COMMON DRUG REGIMEN IN PRIMARY ANTI-TB DRUGS

RIFAMPICIN AND ISONIAZID

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41

WITH RIFAMPICIN AND ISONIAZID HOW LONG WILL THE TREATMENT FOR M. TUBERCULOSIS TAKE?

9 MONTHS

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42

ADDITIONAL OF PYRAZINAMIDE IN RIFAMPICIN AND ISONIAZID CAN SHORTEN THE TREATMENT DOWN TO HOW MANY MONTHS?

6 MONTHS

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43

TRUE OR FALSE. ADDING ETHAMBUTOL AND STREPTOMYCIN ALONG WITH RIFAMPICIN, ISONIAZID, PYRAZINAMIDE CAN SHORTEN THE TREATMENT TIME FOR 3 MONTHS

FALSE

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44

WHAT ARE THE SECOND LINE ANTI-TB DRUGS

AMIKACIN, KANAMYCIN, CAPREOMYCIN

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45

WHAT ARE THE THIRD-LINE ANTI-TB DRUGS

RIFABUTIN, MACROLIDES, LINEZOLID

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46

MDR-TB ARE USUALLY RESISTANT TO?

RIFAMPICIN AND ISONIAZID

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47

XDR-TB SHOWS RESISTANCE AGAINST

ISONIAZID, RIFAMPICIN, FLUOROQUINONES

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48

WHAT KIND OF TUBERCULOSIS SHOWS RESISTANCE AGAINST ONE OF THE 3 SECONDARY ANTI-TB DRUGS

EXTENSIVELY DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS

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49

WHAT KIND OF TUBERCULOSIS SHOWS RESISTANCE TO AT LEAST TWO PRIMARY ANTI-TB DRUG

MULTIDRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS

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50

A TEST AGAINST MYCOBACTERIUM TUBERCULOSIS

TUBERCULIN SKIN TEST

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51

TUBERCULIN SKIN TEST IS A PROTEIN EXTRACTED AND PURIFIED FROM THE ______ OF CULTURED M. TUBERCULOSIS

CELL WALL

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52

WHAT KIND OF TEST IS TUBERCULIN SKIN TEST?

HYPERSENSITIVITY TEST

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53

WHAT IS THE MEANING PPD

PURIFIED PROTEIN DERIVATIVES

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54

A POSITIVE RESULT OF TUBERCULIN SKIN TEST INDICATES WHAT?

PAST EXPOSURE TO MYCOBACTERIUM TUBERCULOSIS

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55

THIS IS A PREFERRED SKIN TEST METHOD FOR M. TUBERCULOSIS

MANTOUX TEST

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56

HOW MUCH OF PPD IS USED IN MANTOUX TEST?

0.1ML

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57

IN MANTOUX TEST, PPD IS INJECTED ________ AND REACTION IS OBSERVED AFTER _______

INTRADERMALLY; 48 HOURS

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58

POSITIVE RESULT OF MANTOUX TEST

ERYTHEMA AND SWELLING

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59

SIZE OF SWELLING IN POSITIVE REACTION OF MANTOUX TEST

2-10MM IN DIAMETER OR MORE

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60

A SCRATCH METHOD OF TUBERCULIN SKIN TEST

VON PIRQUET TEST

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61

THIS METHOD OF TUBERCULIN SKIN TEST IS PERFORMED AMONG INFANTS

VOLLMER’S TUBERCULIN PATCH TEST

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62

THIS METHOD OF TUBERCULIN SKIN TEST IS A MULTI-PUNCTURE METHOD

TUBERCULIN TINE TEST

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63

TUBERCULIN TINE TEST USES _____ WHICH IS COVERED/COATED WITH _______

4 TINES; DRIED PPD

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64

MYCOBACTERIUM BOVIS CAUSES TB IN?

CATTLE, DOGS, CATS, SWINE, PARROTS, AND HUMAN

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65

MYCOBACTERIUM BOVIS IS ASSOCIATED WITH?

INGESTION OF UNPASTEURIZED COW’S MILK

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66

WHICH IS A SOURCE OF TB VACCINE FOR HUMAN

MYCOBACTERIUM BOVIS

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67

WHAT DOES BCG VACCINE MEAN?

BACILLUS OF CALMETTE AND GUERIN VACCINE

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68

M. BOVIS IS A SOURCE OF TB VACCINE BECAUSE M. BOVIS AND M. TUBERCULOSIS SHOWS SIMILAR?

ANITGENIC DETERMINANTS

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69

M. BOVIS GROWS AT WHAT TEMP?

35-37C

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70

MEDIA FOR M. BOVIS

MIDDLEBROOK MEDIA AND LOWENSTEIN JENSEN MEDIA

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71

IN MIDDLEBROOK MEDIA, M. BOVIS IS EVIDENT FOR HOW LONG?

3 WEEKS

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72

IN LJ MEDIA, M. BOVIS IS EVIDENT FOR HOW LONG?

6-8 WEEKS

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73

IN LJ MEDIA, WHAT IS THE APPEARANCE OF M. BOVIS?

WATER DROPLET APPEARANCE

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74

IN WHAT TEMP DOES M. BOVIS SHOWS NO GROWTH?

24-42C

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75

WHAT TEST CAN HELP DIFFERENTIATE M. BOVIS FROM M. TUBERCULOSIS?

NIACIN TEST, NITRATE REDUCTION TEST, PYRAZINAMIDASE TEST

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76

IN NIACIN TEST, NITRATE REDUCTION TEST, PYRAZINAMIDASE TEST WHICH BACTERIA SHOWS NEGATIVE REACTION IN ALL THESE TEST?

MYCOBACTERIUM BOVIS

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77

A BACTERIA ASSOCIATED WITH TB IN TROPICAL AFRICA

MYCOBACTERIUM AFRICANUM

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78

TUBERCULOSIS THAT IS SEEN IN CHILDREN WITH AIDS

MYCOBACTERIUM CANETTII

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79

TUBERCULOSIS IN BOTH IMMUNOCOMPETENT AND IMMUNOCOMPROMISED INDIVIDUAL

MYCOBACTERIUM MICROTI

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80

WHAT IS THE AGENT OF TUBERCULOSIS IN ANIMALS

MYCOBACTERIUM MICROTI

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81

IT IS/ARE THE FIRST ISOLATED FROM ANIMALS BUT MAY ALSO BE TRANSMITTED TO HUMAN

MYCOBACTERIUM PINNIPEDII AND MYCOBACTERIUM CAPRAE

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82

WHERE CAN MOTT BE FOUND?

ENVIRONMENT

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83

MOTT ARE GROUPED BASED ON?

RUNYOUN’S CLASSIFICATION

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84

THIS SHOWS YELLOW PIGMENT WHEN EXPOSED TO CONSTANT LIGHT

GROUP 1 - PHOTOCHROMOGEN

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85

THIS SHOWS YELLOW-TO-ORANGE PIGMENT IN DARK AND UNDER LIGHT

GROUP 2 - SCOTOCHROMOGEN

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86

THEY ARE NON PIGMENTED BOTH IN DARK AND LIGHT

GROUP 3 - NON-PHOTOCHROMOGEN

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87

SINCE GROUP 4 RAPID GROWERS HAVE VARYING PIGMENTATION THEIR KEY CHARACTERISTICS IS THAT THEIR GROWTH RATE IS AT?

3-5 DAYS

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88

WHICH OF THE MOTT HAVE A GROWTH RATE OF 10-21 DAYS

PHOTOCHROMOGEN, SCOTOCHROMOGEN, NON-PHOTOCHROMOGEN

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89

WHAT BACTERIA IS ALSO KNOWN AS THE YELLOW BACILLUS

MYCOBACTERIUM KANSASII

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90

M. KANSASII PRODUCES YELLOW PIGMENT WHEN EXPOSED TO LIGHT DUE TO THE PRESENCE OF?

BETA-CAROTENE

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91

A DERIVATIVE OF VITAMIN A THAT CAN BE FOUND IN YELLOW BACILLUS

BETA-CAROTENE

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92

YELLOW PIGMENT OF MYCOBACTERIUM KANSASII IS ONLY EVIDENT ON?

YOUNG CULTURE

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93

IF PROLONGED INCUBATION ON EXPOSED LIGHT OF M. KANSASII, THE PIGMENT MAY CHANGE TO WHAT COLOR?

RED

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94

WHAT IS THE SECOND COMMON CAUSE OF NONTUBERCULOUS MYCOBACTERIUM LUNG DISEASE AMONG AIDS PATIENT

MYCOBACTERIUM KANSASII

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95

APPEARANCE OF YELLOW BACILLUS WHEN SEEN IN MICROSCOPE

SHEPHERD’S HOOK OR CANDY CANE APPEARANCE

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96

M. KANSASII GROWS WELL AT WHAT TEMP?

37C

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97

GROWTH OF YELLOW BACILLUS IS EVIDENT AFTER HOW MANY DAYS?

14-28 DAYS

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98

SLOW GROWTH OF YELLOW BACILLUS IS SEEN IN WHAT TEMP?

24C

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99

M. KANSASII IS RAPID TWEEN 80 HYDROLYSIS POSITIVE BECAUSE THEY CAN HYDROLYZE TWEEN 80 WITHIN?

3 DAYS

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100

MOST BACTERIA CAN HYDROLYZE TWEEN 80 WITHIN?

10 DAYS

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