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GRAM POSITIVE OR GRAM NEGATIVE. MYCOBACTERIA SPECIES
GRAM POSITIVE
TRUE OR FALSE. MYCOBACTERIA SPECIES ARE GRAM (+), ACID-FAST, SLENDER, THIN COCCI
FALSE
FOR PATHOGENIC MYCOBACTERIA SPECIES, THEY REQUIRE HOW MANY DAYS FOR IT TO SHOW EVIDENT GROWTH IN A CULTURE MEDIA?
MORE THAN 5 DAYS
SINCE MYCOBACTERIA SPECIES REQUIRE HIGH PROTEIN CONTENT, WHAT DO THEY NEED FOR GROWTH?
WHOLE EGG
NON PATHOGENIC MYCOBACTERIUM SPECIES ARE WHAT KIND OF GROWERS?
RAPID GROWERS
WHAT MYCOBACTERIA SPECIE IS A NON-CULTURABLE IN VITRO?
MYCOBACTERIUM LEPRAE
WHAT IS USED TO CULTURE MYCOBACTERIUM LEPRAE?
FOOTPADS OF ARMADILLO OR FOOTPADS OF MOUSE
SINCE MYCOBACTERIUM SPECIES HAVE A HIGH LIPID-CONTAINING CELL WALL, THEY ARE REGARDED AS?
ACID-FAST
TRUE OR FALSE. WHEN MYCOBACTERIUM SPECIES ARE STAINED, THEY ARE MORE DIFFICULT TO DECOLORIZE ESPECIALLY WITH THE USE OF ACID ALCOHOL
TRUE
MYCOBACTERIUM TUBERCULOSIS IS ALSO KNOWN AS?
KOCH’S BACILLUS OR TUBERCLE BACILLUS
M. TUBERCULOSIS WAS FIRST DESCRIBED BY?
ROBERT KOCH (1882)
WHAT IS THE INCLUSION BODY OF M. TUBERCULOSIS
MUCH GRANULES
COLONY APPEARANCE OF MYCOBACTERIUM TUBERCULOSIS
CAULIFLOWER LIKE
THE COLONY APPEARANCE OF M. TUBERCULOSIS IS EVIDENT WHEN INCUBATED AT WHAT TEMP?
35-37C
ASIDE FROM M. TUBERCULOSIS BEING OBLIGATE AEROBE, THEY ALSO REQUIRE ______ FOR GROWTH
5-10% CARBON DIOXIDE
THIS IS THE PRINCIPAL AGENT OF TUBERCULOSIS IN MAN
MYCOBACTERIUM TUBERCULOSIS
MODE OF TRANSMISSION OF M. TUBERCULOSIS
INHALATION OF VIABLE BACILLI
ONLY ____ OF INFECTED INDIVIDUAL DEVELOPS A DISEASE
15-20%
WHAT DISEASE REMAINS AS ONE OF THE MOST LEADING CAUSE OF MORTALITY AND MORBIDITY WORLDWIDE
TUBERCULOSIS
______ OF THE WORLD’S POPULATION IS INFECTED WITH M. TUBERCULOSIS
1/3
WHAT IS THE VIRULENCE FACTOR OF M. TUBERCULOSIS
CORD FACTOR
CORD FACTOR IS ALSO KNOWN AS?
SERPENTINE FACTOR
THE VIRULENCE FACTOR OF M. TUBERCULOSIS IS MADE UP OF?
TREHALOSE DIMYCOLATE
THIS VIRULENCE FACTOR INHIBITS LEUKOCYTE MIGRATION
CORD FACTOR
WHAT DO YOU CALL WHEN A WBC MIGRATES TO THE SITE OF INFECTION
CHEMOTAXIS
CORD FACTOR ACTIVATES ________ CREATING ________
MACROPHAGE; GRANULOMA FORMATION
WHAT DO YOU CALL THE SCAR FORMATION CAUSED BY M. TUBERCULOSIS
GHON LESIONS
CORD FACTORS INDUCES RELEASE?
TUMOR NECROSIS FACTOR ALPHA (TNF-ALPHA)
CORD FACTOR CAUSES MYCOBACTERIUM TUBERCULOSIS TO HAVE ______ UNDER THE MICROSCOPE
PARALLEL ARRANGEMENT
SULFATIDE INHIBITS WHAT?
PHAGOLYSOSOMAL FUSION
THIS IS USUALLY SEEN IN CHILDREN AND PATIENTS WHO HAS INITIAL EXPOSURE
PRIMARY TUBERCULOSIS
A PRIMARY TUBERCULOSIS THAT HAS NO APPARENT SIGNS AND SYMPTOMS, NOT INFECTIOUS
LATENT TUBERCULOSIS
A PRIMARY TUBERCULOSIS THAT OCCURS WHEN IMMUNE SYSTEM IS SUPPRESSED
REACTIVATION TUBERCULOSIS
THIS IS WHEN PATIENTS WHO ACQUIRED TUBERCULOSIS FROM ANOTHER INDIVIDUAL WITH TUBERCULOSIS
SECONDARY TUBERCULOSIS
MILITARY TUBERCULOSIS IS ALSO KNOWN AS?
MENINGEAL TB, DISSEMINATED TB
MILITARY TUBERCULOSIS IS A TYPE OF WHAT TB?
EXTRA PULMONARY TUBERCULOSIS
TUBERCULOSIS OF THE SPINE
POTT’S DISEASE
WHAT IS THE OTHER TERM FOR POTT’S DISEASE
TUBERCULAR SPONDYLITIS, SKELETAL TB
PRIMARY ANTI-TB DRUGS
RIFAMPICIN, ISONIAZID, PYRAZINAMIDE, ETHAMBUTOL (STREPTOMYCIN)
WHAT IS/ARE THE MOST COMMON DRUG REGIMEN IN PRIMARY ANTI-TB DRUGS
RIFAMPICIN AND ISONIAZID
WITH RIFAMPICIN AND ISONIAZID HOW LONG WILL THE TREATMENT FOR M. TUBERCULOSIS TAKE?
9 MONTHS
ADDITIONAL OF PYRAZINAMIDE IN RIFAMPICIN AND ISONIAZID CAN SHORTEN THE TREATMENT DOWN TO HOW MANY MONTHS?
6 MONTHS
TRUE OR FALSE. ADDING ETHAMBUTOL AND STREPTOMYCIN ALONG WITH RIFAMPICIN, ISONIAZID, PYRAZINAMIDE CAN SHORTEN THE TREATMENT TIME FOR 3 MONTHS
FALSE
WHAT ARE THE SECOND LINE ANTI-TB DRUGS
AMIKACIN, KANAMYCIN, CAPREOMYCIN
WHAT ARE THE THIRD-LINE ANTI-TB DRUGS
RIFABUTIN, MACROLIDES, LINEZOLID
MDR-TB ARE USUALLY RESISTANT TO?
RIFAMPICIN AND ISONIAZID
XDR-TB SHOWS RESISTANCE AGAINST
ISONIAZID, RIFAMPICIN, FLUOROQUINONES
WHAT KIND OF TUBERCULOSIS SHOWS RESISTANCE AGAINST ONE OF THE 3 SECONDARY ANTI-TB DRUGS
EXTENSIVELY DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS
WHAT KIND OF TUBERCULOSIS SHOWS RESISTANCE TO AT LEAST TWO PRIMARY ANTI-TB DRUG
MULTIDRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS
A TEST AGAINST MYCOBACTERIUM TUBERCULOSIS
TUBERCULIN SKIN TEST
TUBERCULIN SKIN TEST IS A PROTEIN EXTRACTED AND PURIFIED FROM THE ______ OF CULTURED M. TUBERCULOSIS
CELL WALL
WHAT KIND OF TEST IS TUBERCULIN SKIN TEST?
HYPERSENSITIVITY TEST
WHAT IS THE MEANING PPD
PURIFIED PROTEIN DERIVATIVES
A POSITIVE RESULT OF TUBERCULIN SKIN TEST INDICATES WHAT?
PAST EXPOSURE TO MYCOBACTERIUM TUBERCULOSIS
THIS IS A PREFERRED SKIN TEST METHOD FOR M. TUBERCULOSIS
MANTOUX TEST
HOW MUCH OF PPD IS USED IN MANTOUX TEST?
0.1ML
IN MANTOUX TEST, PPD IS INJECTED ________ AND REACTION IS OBSERVED AFTER _______
INTRADERMALLY; 48 HOURS
POSITIVE RESULT OF MANTOUX TEST
ERYTHEMA AND SWELLING
SIZE OF SWELLING IN POSITIVE REACTION OF MANTOUX TEST
2-10MM IN DIAMETER OR MORE
A SCRATCH METHOD OF TUBERCULIN SKIN TEST
VON PIRQUET TEST
THIS METHOD OF TUBERCULIN SKIN TEST IS PERFORMED AMONG INFANTS
VOLLMER’S TUBERCULIN PATCH TEST
THIS METHOD OF TUBERCULIN SKIN TEST IS A MULTI-PUNCTURE METHOD
TUBERCULIN TINE TEST
TUBERCULIN TINE TEST USES _____ WHICH IS COVERED/COATED WITH _______
4 TINES; DRIED PPD
MYCOBACTERIUM BOVIS CAUSES TB IN?
CATTLE, DOGS, CATS, SWINE, PARROTS, AND HUMAN
MYCOBACTERIUM BOVIS IS ASSOCIATED WITH?
INGESTION OF UNPASTEURIZED COW’S MILK
WHICH IS A SOURCE OF TB VACCINE FOR HUMAN
MYCOBACTERIUM BOVIS
WHAT DOES BCG VACCINE MEAN?
BACILLUS OF CALMETTE AND GUERIN VACCINE
M. BOVIS IS A SOURCE OF TB VACCINE BECAUSE M. BOVIS AND M. TUBERCULOSIS SHOWS SIMILAR?
ANITGENIC DETERMINANTS
M. BOVIS GROWS AT WHAT TEMP?
35-37C
MEDIA FOR M. BOVIS
MIDDLEBROOK MEDIA AND LOWENSTEIN JENSEN MEDIA
IN MIDDLEBROOK MEDIA, M. BOVIS IS EVIDENT FOR HOW LONG?
3 WEEKS
IN LJ MEDIA, M. BOVIS IS EVIDENT FOR HOW LONG?
6-8 WEEKS
IN LJ MEDIA, WHAT IS THE APPEARANCE OF M. BOVIS?
WATER DROPLET APPEARANCE
IN WHAT TEMP DOES M. BOVIS SHOWS NO GROWTH?
24-42C
WHAT TEST CAN HELP DIFFERENTIATE M. BOVIS FROM M. TUBERCULOSIS?
NIACIN TEST, NITRATE REDUCTION TEST, PYRAZINAMIDASE TEST
IN NIACIN TEST, NITRATE REDUCTION TEST, PYRAZINAMIDASE TEST WHICH BACTERIA SHOWS NEGATIVE REACTION IN ALL THESE TEST?
MYCOBACTERIUM BOVIS
A BACTERIA ASSOCIATED WITH TB IN TROPICAL AFRICA
MYCOBACTERIUM AFRICANUM
TUBERCULOSIS THAT IS SEEN IN CHILDREN WITH AIDS
MYCOBACTERIUM CANETTII
TUBERCULOSIS IN BOTH IMMUNOCOMPETENT AND IMMUNOCOMPROMISED INDIVIDUAL
MYCOBACTERIUM MICROTI
WHAT IS THE AGENT OF TUBERCULOSIS IN ANIMALS
MYCOBACTERIUM MICROTI
IT IS/ARE THE FIRST ISOLATED FROM ANIMALS BUT MAY ALSO BE TRANSMITTED TO HUMAN
MYCOBACTERIUM PINNIPEDII AND MYCOBACTERIUM CAPRAE
WHERE CAN MOTT BE FOUND?
ENVIRONMENT
MOTT ARE GROUPED BASED ON?
RUNYOUN’S CLASSIFICATION
THIS SHOWS YELLOW PIGMENT WHEN EXPOSED TO CONSTANT LIGHT
GROUP 1 - PHOTOCHROMOGEN
THIS SHOWS YELLOW-TO-ORANGE PIGMENT IN DARK AND UNDER LIGHT
GROUP 2 - SCOTOCHROMOGEN
THEY ARE NON PIGMENTED BOTH IN DARK AND LIGHT
GROUP 3 - NON-PHOTOCHROMOGEN
SINCE GROUP 4 RAPID GROWERS HAVE VARYING PIGMENTATION THEIR KEY CHARACTERISTICS IS THAT THEIR GROWTH RATE IS AT?
3-5 DAYS
WHICH OF THE MOTT HAVE A GROWTH RATE OF 10-21 DAYS
PHOTOCHROMOGEN, SCOTOCHROMOGEN, NON-PHOTOCHROMOGEN
WHAT BACTERIA IS ALSO KNOWN AS THE YELLOW BACILLUS
MYCOBACTERIUM KANSASII
M. KANSASII PRODUCES YELLOW PIGMENT WHEN EXPOSED TO LIGHT DUE TO THE PRESENCE OF?
BETA-CAROTENE
A DERIVATIVE OF VITAMIN A THAT CAN BE FOUND IN YELLOW BACILLUS
BETA-CAROTENE
YELLOW PIGMENT OF MYCOBACTERIUM KANSASII IS ONLY EVIDENT ON?
YOUNG CULTURE
IF PROLONGED INCUBATION ON EXPOSED LIGHT OF M. KANSASII, THE PIGMENT MAY CHANGE TO WHAT COLOR?
RED
WHAT IS THE SECOND COMMON CAUSE OF NONTUBERCULOUS MYCOBACTERIUM LUNG DISEASE AMONG AIDS PATIENT
MYCOBACTERIUM KANSASII
APPEARANCE OF YELLOW BACILLUS WHEN SEEN IN MICROSCOPE
SHEPHERD’S HOOK OR CANDY CANE APPEARANCE
M. KANSASII GROWS WELL AT WHAT TEMP?
37C
GROWTH OF YELLOW BACILLUS IS EVIDENT AFTER HOW MANY DAYS?
14-28 DAYS
SLOW GROWTH OF YELLOW BACILLUS IS SEEN IN WHAT TEMP?
24C
M. KANSASII IS RAPID TWEEN 80 HYDROLYSIS POSITIVE BECAUSE THEY CAN HYDROLYZE TWEEN 80 WITHIN?
3 DAYS
MOST BACTERIA CAN HYDROLYZE TWEEN 80 WITHIN?
10 DAYS
Note 
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