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what do humans use for fuel/energy and cellular function
ATP
how is ATP synthesized
from the breakdown of macronutrients in the diet
how many calories are in 1 gram of carbs, protein, and fat
4 cal/g of carbs
4 cal/g of protein
9 cal/g of fat
how are carbs absorbed
as glucose primarily but fructose and galactose also contribute
how are fats absorbed as
fatty acids
triglycerides
cholesterol
what are proteins broken down into in the body
amino acids and small peptides for absorption
are carbs used to create energy anaerobically or aerobically
both
what is the anaerobic metabolism process of carbohydrates
glucose undergoes glycolysis to produce 2 ATP and two pyruvic acid
what occurs in glycolysis if the initial fuel is glycogen
3 ATP is yielded
what is the aerobic metabolism of carbohydrates
the pyruvic acid produced from glycolysis enters the krebs cycle to yield 2 ATP and hydrogen ions
what happens to the hydrogen ions produced from Krebs cycle
they are transported to the electron transport chain where they produce 30-32 ATP molecules
triglycerides
the storage form of fat
what does hydrolysis do to triglycerides
releases fatty acids and glycerol
where does the glycerol from hydrolysis of triglycerides go
it can enter the metabolic pathway for glucose and yield 19 ATP
how are fatty acids broken down
through beta oxidation to form acetyl CoA which then enters the Krebs cycle
what happens to acetyl CoA in Krebs cycle
it combines with oxaloacetic acid from carb metabolism to form citric acid and continue through the cycle to produce ATP
how much ATP can complete oxidation of fatty acids yield
441 ATP
what does protein metabolism use fuel for
endurance activities lasting longer than 90 minutes
what is deamination
a process that occurs to proteins where the amine group is removed
what is transamination
removal of nitrogen that leaves behind a carbon skeleton
what occurs to the carbon skeleton left behind from deamination and transamination
they can be converted into glucose through gluconeogenesis to provide ATP
what is glycolysis
the anaerobic breakdown of glucose into pyruvate, ATP, and NADH
what is the Krebs cycle (citric acid cycle)
processes acetyl CoA to produce ATP, ADH, and FADH2
what is oxidative phosphoralization
uses energy from NADH and FADH2 to generate ATP in the presence of oxygen
what does the phosphagen system provide
immediate energy for short bursts through creatine phosphate breakdown
what does the aerobic system provide
sustains lower intensity activities over longer periods using oxygen to metabolize macronutrients to ATP
what are the three main metabolic pathways for energy
phosphagen (ATP phosphocreatine)
anaerobic glycolysis
aerobic metabolism (oxidative phosphorylation)
what does the phosphocreatine system provide
rapid but unlimited supply of ATP that peaks in the initial seconds of high intensity exercise
how long does the phosphocreatine system work
during the first 30 seconds of intense exercise
does the phosphocreatine system still function after the initial start of high intensity exercise
yes it still produces ATP but at a lesser extent
what does anaerobic glycolysis provide
provides energy starting almost immediately and ramping up ATP production as phosphocreatine stores decline
how long does the anaerobic glycolytic system work
30 seconds-2 min
what does oxidative phosphorylation provide
efficient but slow energy that increases as activity continues especially during lower energy exercise
how long does the aerobic system provide energy
predominately after 2 minutes of exercise
what is the difference in ATP output in anaerobic and aerobic metabolism
anaerobic metabolism is faster but only yields 2 ATP per glucose molecule
aerobic metabolism is slower but yields 30-32 ATP per glucose molecule
what does accumulation of metabolic byproducts in anaerobic metabolism do
it can hinder muscle performance
what determines the amount of ATP produced from fatty acids
the length of the fatty acid
what occurs to pyruvate when oxygen is present
it is converted to lactate to allow for continued ATP production
where is energy derived from at lower levels of exercise (less than 70% oxygen consumption)
60% from fats
40% from glucose
where is energy derived from in higher intensity exercise (greater than 70% oxygen consumption)
primarily carbohydrates
what occurs to insulin secretion during exercise
it is suppressed so muscle use GLUT4 transporters for glucose uptake bypassing the need for insulin
maximum oxygen uptake (VO2 max)
the maximum volume of oxygen that can be takin in, transported, and utilized by the body during intense exercise
oxygen consumption
the rate at which the body uses oxygen
what is the body's oxygen consumption at rest
3.5 mm per kg per minute (1 MET)
what occurs to oxygen consumption as we exercise
it proportionally rises with intensity of activity reaching a peak at max oxygen consumption
what does the peak oxygen consumption represent (VO2 max)
the efficiency of the heart, lungs, and muscles in delivering and utilizing oxygen
what occurs to oxygen consumption after exercise
it gradually decreases but remains elevated for a period to restore homeostasis, replenish energy stores, and remove metabolic byproducts
what does a high VO2 max indicate
a greater ability to perform endurance exercise
what is Ficks principle
VO2max= max CO x arteriovenous oxygen difference
what does 2 METs mean
a person is consuming oxygen at twice the resting rate
how is VO2 max tested
an individual wears a mouthpiece or mask connected to a spirometer that measures the volume and composition of expired air
what are tests that can be used to estimate VO2 max
cooper walk/run test
1.5 mile run test
step test
Rockport walk test
cooper walk/run test
run or walk as far as possible in 12 minutes
1.5 mile run test
run 1.5 miles as quickly as possible
step test
step up and down on a platform for 3 minutes
Rockport walk test
walk one mile as quickly as possible
balance
ability to maintain or move the body within its BOS without falling
cardiopulmonary endurance
the ability to sustain moderate intensity activities over time
coordination
the precise timing and sequencing of muscle activation for smooth movement
flexibility and mobility
the ability to move freely and achieve the necessary ROM for activities
muscle performance
the muscles capacity to produce tension, encompassing strength, power, and endurance
neuromuscular control
the effect of interaction between sensory and motor systems for coordinated movement
stability
ability to hold or control body segments during movement
what is therapeutic exercise
the systematic performance of planned physical movements of activities intended to enable the patient or client to:
-prevent or remediate impairments of body structure and function
- enhance activities or participation
- prevent or reduce health related risk factors
- optimize overall health status, fitness, or sense of well being
how does the ICF model contribute to therapeutic exercise prescription
provides a comprehensive view of the patients overall health and function
what do the patients goals directly relate to in the ICF model
participation restrictions
when prescribing exercise what part of the ICF model is targeted to write SMARTF goals for the plan of care to adress
impairments/functional limitations
what is the purpose of performing regular exercise
to achieve a positive adaptation in physical function
what are the goals of treatment for the acute/protective phase
POLICE
patient education
posture
rest/relative rest
gentle mobility
submaximal isometrics
what is the goal of treatment during subacute/controlled motion phase
regain ROM/flexibility
gradually load tissues, introduce resistive stress
neuro reeducation/activation patterns
what is the goal of treatment in the settled/return to function or sport phase
progressive loading to heavier loads
functional specific strengthening and loading
plyometrics
mimic functional/sport demands
what is the overload principle
to improve any aspect of physical fitness the body must be challenged with a workload greater than it is accustomed to
what s the SAID principle
states that exercise training programs should be built on specificity
the adaptive effects of training are specific to the type of exercise preformed
what is the reversibility principle
adaptive changes from resistance exercises are temporary, unless maintained through regular functional activities or a consistent maintenance program
when does reduces muscle performance (detraining) occur
within 1-2 weeks after stopping resistance exercises
when does a loss of training effects occur
within 2-4 weeks of stopping resistance exercise
what can help to engage patients in a lifelong maintenance program of exercise
integrate strength and endurance gains into daily activities and rehabilitation
what two factors can influence how a patient responds to exercise
environmental and personal factors
what is FITTVP
frequency
intensity
time
type
volume
progression
exercise intensity
how hard a person is working during exercise
how can exercise intensity be measured
HR
RPE
Counting Talk Test
METs
% of 1 rep max
what is submaximal loading
involved using a lighter load or lower intensity often used to build endurance
what is maximal loading
higher load or intensity used to increase maximal speed or force output
how is exercise intensity determined for patients
desired outcomes
individuals fitness level
goals
what is time in relation to exercise
how long the individual is working during a bout of exercise or the total exposure to exercise stimulus during a workout
what are some ways time can be recorded during exercise
it can be a set time or exercise
sets and reps also measure time
also includes the rest interval between sets or between exercises
what is a repetition
the number of times a particular movement is repeated or the number of muscle contractions to perform to move the limb through a motion against a specific load
what is a set
a predetermined number of repetitions grouped together
what is volume in terms of exercise
a measure of the overall stress of the exercise prescription
how is exercise volume calculated
the product of frequency, sets, repetitions, and intensity
what should be considered about volume when prescribing exercise
consider the prescribed exercise as well as other physical activities and non exercise related physical stress
what is a progression in exercise
increasing the dosage of exercise over time as the individual adapts
how can exercises be progressed
by increasing any component of FITTVP
what should be focused on when progressing exercise
focus on performance improvements rather than adding stress
what components of exercise should be progressed first
time or duration before intensity or frequency
what are behavioral/psychological/lifestyle factors that can impact exercise
sedentary lifestyle
poor nutrition
use of tobacco, alcohol, drugs
low motivation
inadequate coping skills
difficulty wit change
what are examples of physical environment characteristics that can impact exercise
architecture barriers
ergonomic characteristics
what are examples of socioeconomic factors that can impact exercise
economic status
education level
healthcare access
family or social support
what are the 5 key domains of the social determinants of health
economic stability
education access and quality
healthcare access and quality
neighborhood and build environment
social and community context
what are the two key steps to a structured approach to exercise prescription and progression
continuous assessment and adaptation
thoughtful manipulation of exercise variables