Bioenergetics - MCAT

What steps of glycolysis are reversible?

1, 3, and 10

What is step 1 in glycolysis?

hexokinase transfers phosphate from ATP to glucose, which creates glucose 6-phosphate

Step 2 in glycolysis

convert glucose 6-phosphate to fructose phosphate by isomerization

Step 3 in glycolysis

Add a phosphate to fructose 6-phosphate to create fructose 1,6-bisphosphate

What enzyme is involved in step 3 of glycolysis?

phosphofructiokinase

Step 4 of glycolysis

Cleave fructose 1,6 bisphosphate into glyceraldehyde 3-phosphate and dihydroxyacetone-phosphate

Step 5 of glycolysis

Convert dihydroxyacetone-phosphate into glyceraldehyde 3-phosphate giving you 2 GAP

Step 6 of glycolysis

Convert glyceraldehyde 3-phosphate into 1,3 biphosphoglycerate

Step 7 of glycolysis

Remove a phosphate from 1,3 biphosphoglycerate and turn it into 3-phosphoglycerate

Step 8 of glycolysis

3-phosphoglycerate is isomerized into 2-phosphoglycerate

Step 9 of glycolysis

2-phosphoglycerate is isomerized into phosphoenolpyruvate

Step 10 of glycolysis

Pyruvate kinase converts phosphoenolpyruvate into pyruvate