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Why use CT for PET/CT?
Calculate attenuation correction factors
Where is the collimator located on a PET system?
NO collimator! Old PETs had them, but new PETs do not
How is spatial location found in PET?
Coincident circuit finds time difference between incidences in 180o opposing BGO scintillator detectors.
What is difference between PET and SPECT? (attenuation corrections)
PET : 511 keV from positron. MAJOR interpolation correction for attenuation (511 ←→ 72 keV CT)
SPECT: 140 keV from Tc-99m: MINOR interpolation correction for attenuation (140 ←→ 72)
What is difference between PET and SPECT? (injected material)
PET: F-18-FDG (FluoroDeoxyGlucose)
SPECT: Whatever isotope, typically Tc-99m
Why must interpolation be done on PET image?
Quantitative image
Which has better spatial resolution, PET or SPECT?
SPECT, it has a collimator
Why use PET/MRI vs. PET/CT?
MRI is better for soft tissue contrast.
Can use MRI at SAME TIME as PET, NO pixel shift, CT has to correct for pixel shift.
No Radiation
How is PET merged with CT?
Volume fusion
How much dose does a patient typically recieve?
~25 mSv per scan
How is the fundamental spatial resolution of PET determined?
The range of positron emitted from F-18 (in FDG) is ~2.2mm