Mechanisims of viral virulence and host resistence

the ability to cause disease is known as ___________

pathogenicity

a measure of pathogenicity of viruses or how bad the clinical signs will be is known as ____________

virulence

virulence can manifest in what ways

• asymptomatic

• death

• mild, moderate or severe

what factors impact virulence

• infectious dose

• route of infection

• tissue tropism

• virus dissemination

• genetic determinants

tissue tropism is considered when thinking of if the tissues have the ________ and ability to ________ the virus

• receptors

• replicate

viruses with the ability to infect multiple cell types and multiple organ systems is known as what?

pantropism

what factors impact host resistance or susceptibility

• expression of receptors

• cell activity

• immune status

• age

• nutrition

• husbandry conditions

What aspects of cell activity affect susceptibility

• replication

• stage of differentiation